Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein LJ Marnett, JN Riggins, JD West The Journal of Clinical Investigation 111 (5), 583-593, 2003 | 609 | 2003 |
Endogenous reactive intermediates as modulators of cell signaling and cell death JD West, LJ Marnett Chemical Research in Toxicology 19 (2), 173-194, 2006 | 375 | 2006 |
Activation of heat shock and antioxidant responses by the natural product celastrol: transcriptional signatures of a thiol-targeted molecule A Trott, JD West, L Klaić, SD Westerheide, RB Silverman, RI Morimoto, ... Molecular Biology of the Cell 19 (3), 1104-1112, 2008 | 264 | 2008 |
Alterations in gene expression induced by the lipid peroxidation product, 4-hydroxy-2-nonenal JD West, LJ Marnett Chemical Research in Toxicology 18 (11), 1642-1653, 2005 | 154 | 2005 |
Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation JD West, C Ji, ST Duncan, V Amarnath, C Schneider, CJ Rizzo, AR Brash, ... Chemical Research in Toxicology 17 (4), 453-462, 2004 | 88 | 2004 |
The yeast Hsp70 Ssa1 is a sensor for activation of the heat shock response by thiol-reactive compounds Y Wang, PA Gibney, JD West, KA Morano Molecular Biology of the Cell 23 (17), 3290-3298, 2012 | 75 | 2012 |
Small Molecule Activators of the Heat Shock Response: Chemical Properties, Molecular Targets, and Therapeutic Promise JD West, Y Wang, KA Morano Chemical Research in Toxicology 25 (10), 2036–2053, 2012 | 68 | 2012 |
Modulation of DNA fragmentation factor 40 nuclease activity by poly (ADP-ribose) polymerase-1 JD West, C Ji, LJ Marnett Journal of Biological Chemistry 280 (15), 15141-15147, 2005 | 36 | 2005 |
Enhanced Toxicity of the Protein Cross-Linkers Divinyl Sulfone and Diethyl Acetylenedicarboxylate in Comparison to Related Monofunctional Electrophiles JD West, CE Stamm, HA Brown, SL Justice, KA Morano Chemical Research in Toxicology 24 (9), 1457–1459, 2011 | 31 | 2011 |
Redox requirements for ubiquitin-like urmylation of Ahp1, a 2-Cys peroxiredoxin from yeast C Brachmann, L Kaduhr, A Jüdes, KE Ravichandran, JD West, S Glatt, ... Redox biology 30, 101438, 2020 | 19 | 2020 |
Trapping redox partnerships in oxidant-sensitive proteins with a small, thiol-reactive cross-linker KM Allan, MA Loberg, J Chepngeno, JE Hurtig, S Tripathi, MG Kang, ... Free Radical Biology and Medicine 101, 356-366, 2016 | 19 | 2016 |
Bifunctional Electrophiles Cross-Link Thioredoxins with Redox Relay Partners in Cells MR Naticchia, HA Brown, FJ Garcia, AM Lamade, SL Justice, RP Herrin, ... Chemical Research in Toxicology 26 (3), 490-497, 2013 | 17 | 2013 |
Piecing Together How Peroxiredoxins Maintain Genomic Stability JD West, TJ Roston, JB David, KM Allan, MA Loberg Antioxidants 7 (12), 177, 2018 | 16 | 2018 |
Structure−Activity Comparison of the Cytotoxic Properties of Diethyl Maleate and Related Molecules: Identification of Diethyl Acetylenedicarboxylate as a Thiol Cross-Linking Agent JD West, CE Stamm, PJ Kingsley Chemical Research in Toxicology 24 (1), 81-88, 2010 | 14 | 2010 |
Aromatic Residues at the Dimer-Dimer Interface in the Peroxiredoxin Tsa1 Facilitate Decamer Formation and Biological Function MA Loberg, JE Hurtig, AH Graff, KM Allan, JA Buchan, MK Spencer, ... Chemical Research in Toxicology 32 (3), 474-484, 2019 | 12 | 2019 |
Pronounced Toxicity Differences between Homobifunctional Protein Cross-Linkers and Analogous Monofunctional Electrophiles MK Spencer, NP Radzinski, S Tripathi, S Chowdhury, RP Herrin, ... Chemical Research in Toxicology 26 (11), 1720-1729, 2013 | 10 | 2013 |
Experimental Approaches for Investigating Disulfide-Based Redox Relays in Cells JD West Chemical Research in Toxicology 35 (10), 1676-1689, 2022 | 7 | 2022 |
Identifying Interaction Partners of Yeast Protein Disulfide Isomerases Using a Small Thiol-Reactive Cross-Linker: Implications for Secretory Pathway Proteostasis BJ Freije, WM Freije, TU Do, GE Adkins, A Bruch, JE Hurtig, KA Morano, ... Chemical Research in Toxicology 35 (2), 326-336, 2022 | 3 | 2022 |
Urm1, not quite a ubiquitin-like modifier? L Kaduhr, C Brachmann, KE Ravichandran, JD West, S Glatt, R Schaffrath Microbial Cell 8 (11), 256-261, 2021 | 3 | 2021 |
Broader than expected tolerance for substitutions in the WCGPCK catalytic motif of yeast thioredoxin 2 SL Vicker, EN Maina, AK Showalter, N Tran, EE Davidson, MR Bailey, ... Free Radical Biology and Medicine 178, 308-313, 2022 | 1 | 2022 |