Novel theranostic opportunities offered by characterization of altered membrane lipid metabolism in breast cancer progression M Hilvo, C Denkert, L Lehtinen, B Müller, S Brockmöller, ... Cancer research 71 (9), 3236-3245, 2011 | 558 | 2011 |
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX V Alterio, M Hilvo, A Di Fiore, CT Supuran, P Pan, S Parkkila, A Scaloni, ... Proceedings of the National Academy of Sciences 106 (38), 16233-16238, 2009 | 553 | 2009 |
Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol R Laaksonen, K Ekroos, M Sysi-Aho, M Hilvo, T Vihervaara, D Kauhanen, ... European heart journal 37 (25), 1967-1976, 2016 | 531 | 2016 |
Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes M Hilvo, L Baranauskiene, AM Salzano, A Scaloni, D Matulis, A Innocenti, ... Journal of Biological Chemistry 283 (41), 27799-27809, 2008 | 368 | 2008 |
Circulating ceramides predict cardiovascular outcomes in the population-based FINRISK 2002 cohort AS Havulinna, M Sysi-Aho, M Hilvo, D Kauhanen, R Hurme, K Ekroos, ... Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2424-2430, 2016 | 293 | 2016 |
Characterization of CA XV, a new GPI-anchored form of carbonic anhydrase M Hilvo, M Tolvanen, A Clark, B Shen, GN Shah, A Waheed, P Halmi, ... Biochemical journal 392 (1), 83-92, 2005 | 244 | 2005 |
Development and validation of a ceramide-and phospholipid-based cardiovascular risk estimation score for coronary artery disease patients M Hilvo, PJ Meikle, ER Pedersen, GS Tell, I Dhar, H Brenner, B Schöttker, ... European heart journal 41 (3), 371-380, 2020 | 221 | 2020 |
Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress K Ketola, M Hilvo, T Hyötyläinen, A Vuoristo, AL Ruskeepää, M Orešič, ... British journal of cancer 106 (1), 99-106, 2012 | 196 | 2012 |
Remodeling of central metabolism in invasive breast cancer compared to normal breast tissue–a GC-TOFMS based metabolomics study J Budczies, C Denkert, BM Müller, SF Brockmöller, F Klauschen, B Györffy, ... BMC genomics 13, 1-11, 2012 | 163 | 2012 |
Expression of carbonic anhydrase IX in astrocytic tumors predicts poor prognosis JA Haapasalo, KM Nordfors, M Hilvo, IJ Rantala, Y Soini, AK Parkkila, ... Clinical cancer research 12 (2), 473-477, 2006 | 163 | 2006 |
Susceptibility of low-density lipoprotein particles to aggregate depends on particle lipidome, is modifiable, and associates with future cardiovascular deaths M Ruuth, SD Nguyen, T Vihervaara, M Hilvo, TD Laajala, PK Kondadi, ... European heart journal 39 (27), 2562-2573, 2018 | 159 | 2018 |
Metabolic associations of reduced proliferation and oxidative stress in advanced breast cancer L Jerby, L Wolf, C Denkert, GY Stein, M Hilvo, M Oresic, T Geiger, ... Cancer research 72 (22), 5712-5720, 2012 | 153 | 2012 |
Metabolomics of human breast cancer: new approaches for tumor typing and biomarker discovery C Denkert, E Bucher, M Hilvo, R Salek, M Orešič, J Griffin, S Brockmöller, ... Genome medicine 4, 1-9, 2012 | 127 | 2012 |
The metabolic alterations of cancer cells M Sciacovelli, E Gaude, M Hilvo, C Frezza Methods in enzymology 542, 1-23, 2014 | 124 | 2014 |
Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide A Di Fiore, SM Monti, M Hilvo, S Parkkila, V Romano, A Scaloni, ... Proteins: Structure, Function, and Bioinformatics 74 (1), 164-175, 2009 | 124 | 2009 |
Plasma concentrations of molecular lipid species predict long-term clinical outcome in coronary artery disease patients S Anroedh, M Hilvo, KM Akkerhuis, D Kauhanen, K Koistinen, ... Journal of lipid research 59 (9), 1729-1737, 2018 | 122 | 2018 |
Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses V Aho, HM Ollila, E Kronholm, I Bondia-Pons, P Soininen, AJ Kangas, ... Scientific reports 6 (1), 24828, 2016 | 115 | 2016 |
Phospholipase PLA2G7, associated with aggressive prostate cancer, promotes prostate cancer cell migration and invasion and is inhibited by statins P Vainio, L Lehtinen, T Mirtti, M Hilvo, T Seppänen-Laakso, J Virtanen, ... Oncotarget 2 (12), 1176, 2011 | 115 | 2011 |
Integration of Metabolomics and Expression of Glycerol-3-phosphate Acyltransferase (GPAM) in Breast Cancer Link to Patient Survival, Hormone Receptor Status, and Metabolic … SF Brockmöller, E Bucher, BM Müller, J Budczies, M Hilvo, JL Griffin, ... Journal of proteome research 11 (2), 850-860, 2012 | 112 | 2012 |
Identification of an alternatively spliced isoform of carbonic anhydrase XII in diffusely infiltrating astrocytic gliomas J Haapasalo, M Hilvo, K Nordfors, H Haapasalo, S Parkkila, A Hyrskyluoto, ... Neuro-oncology 10 (2), 131-138, 2008 | 107 | 2008 |