Mechanisms of clonal evolution in childhood acute lymphoblastic leukemia S Swaminathan, L Klemm, E Park, E Papaemmanuil, A Ford, SM Kweon, ... Nature immunology 16 (7), 766-774, 2015 | 222 | 2015 |
BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR–ABL1 kinase inhibition C Duy, C Hurtz, S Shojaee, L Cerchietti, H Geng, S Swaminathan, ... Nature 473 (7347), 384-388, 2011 | 216 | 2011 |
Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia EJ Gang, YT Hsieh, J Pham, Y Zhao, C Nguyen, S Huantes, E Park, ... Oncogene 33 (17), 2169-2178, 2014 | 174 | 2014 |
BCL6 is critical for the development of a diverse primary B cell repertoire C Duy, JJ Yu, R Nahar, S Swaminathan, SM Kweon, JM Polo, E Valls, ... Journal of Experimental Medicine 207 (6), 1209-1221, 2010 | 142 | 2010 |
Erk negative feedback control enables pre-B cell transformation and represents a therapeutic target in acute lymphoblastic leukemia S Shojaee, R Caeser, M Buchner, E Park, S Swaminathan, C Hurtz, ... Cancer cell 28 (1), 114-128, 2015 | 132 | 2015 |
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint S Swaminathan, C Huang, H Geng, Z Chen, R Harvey, H Kang, C Ng, ... Nature medicine 19 (8), 1014-1022, 2013 | 119 | 2013 |
Lipid nanoparticles that deliver IL-12 messenger RNA suppress tumorigenesis in MYC oncogene-driven hepatocellular carcinoma I Lai, S Swaminathan, V Baylot, A Mosley, R Dhanasekaran, M Gabay, ... Journal for immunotherapy of cancer 6, 1-11, 2018 | 108 | 2018 |
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia B Kharabi Masouleh, H Geng, C Hurtz, LN Chan, AC Logan, MS Chang, ... Proceedings of the National Academy of Sciences 111 (21), E2219-E2228, 2014 | 103 | 2014 |
GM-CSF: A double-edged sword in cancer immunotherapy A Kumar, A Taghi Khani, A Sanchez Ortiz, S Swaminathan Frontiers in immunology 13, 901277, 2022 | 101 | 2022 |
MYC functions as a switch for natural killer cell-mediated immune surveillance of lymphoid malignancies S Swaminathan, AS Hansen, LD Heftdal, R Dhanasekaran, A Deutzmann, ... Nature communications 11 (1), 2860, 2020 | 56 | 2020 |
Activated natural killer cells predict poor clinical prognosis in high-risk B-and T-cell acute lymphoblastic leukemia C Duault, A Kumar, A Taghi Khani, SJ Lee, L Yang, M Huang, C Hurtz, ... Blood, The Journal of the American Society of Hematology 138 (16), 1465-1480, 2021 | 44 | 2021 |
Mechanisms of pre‐B‐cell receptor checkpoint control and its oncogenic subversion in acute lymphoblastic leukemia M Buchner, S Swaminathan, Z Chen, M Müschen Immunological reviews 263 (1), 192-209, 2015 | 43 | 2015 |
BACH2–BCL6 balance regulates selection at the pre-B cell receptor checkpoint S Swaminathan, C Duy, M Müschen Trends in immunology 35 (3), 131-137, 2014 | 42 | 2014 |
MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint BAH Smith, A Deutzmann, KM Correa, CS Delaveris, R Dhanasekaran, ... Proceedings of the National Academy of Sciences 120 (11), e2215376120, 2023 | 21 | 2023 |
Hypoxia-inducible factor-1 alpha expression is induced by IL-2 via the PI3K/mTOR pathway in hypoxic NK cells and supports effector functions in NKL cells and ex vivo expanded … E Cluff, CC Magdaleno, E Fernandez, T House, S Swaminathan, ... Cancer Immunology, Immunotherapy, 1-17, 2022 | 17 | 2022 |
Apotheosis, not apocalypse: methods in protein crystallography VS Lamzin, A Perrakis, G Bricogne, J Jiang, S Swaminathan, JL Sussman Acta Crystallographica Section D: Biological Crystallography 56 (11), 1510-1511, 2000 | 15 | 2000 |
TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal Y Li, M Xue, X Deng, L Dong, L Ren, L Han, C Li, J Xue, Z Zhao, W Li, ... Cell Stem Cell 30 (8), 1072-1090. e10, 2023 | 11 | 2023 |
Infectious origins of childhood leukemia S Swaminathan, M Müschen Oncotarget 6 (19), 16798, 2015 | 11 | 2015 |
A mathematical model of tumor regression and recurrence after therapeutic oncogene inactivation SS Hori, L Tong, S Swaminathan, M Liebersbach, J Wang, SS Gambhir, ... Scientific reports 11 (1), 1341, 2021 | 9 | 2021 |
Intrinsic suppression of type I interferon production underlies the therapeutic efficacy of il-15-producing natural killer cells in B-cell acute lymphoblastic leukemia A Kumar, AT Khani, C Duault, S Aramburo, AS Ortiz, SJ Lee, A Chan, ... Journal for Immunotherapy of Cancer 11 (5), 2023 | 8 | 2023 |