Quercetin, a natural flavonoid interacts with DNA, arrests cell cycle and causes tumor regression by activating mitochondrial pathway of apoptosis S Srivastava, RR Somasagara, M Hegde, M Nishana, SK Tadi, ... Scientific reports 6 (1), 1-13, 2016 | 505 | 2016 |
Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules A Ramteke, H Ting, C Agarwal, S Mateen, R Somasagara, A Hussain, ... Molecular carcinogenesis 54 (7), 554-565, 2015 | 387 | 2015 |
Extracts of strawberry fruits induce intrinsic pathway of apoptosis in breast cancer cells and inhibits tumor progression in mice RR Somasagara, M Hegde, KK Chiruvella, A Musini, B Choudhary, ... Public Library of Science 7 (10), e47021, 2012 | 120 | 2012 |
Synthesis of 2-(5-((5-(4-chlorophenyl) furan-2-yl) methylene)-4-oxo-2-thioxothiazolidin-3-yl) acetic acid derivatives and evaluation of their cytotoxicity and induction of … S Chandrappa, CV Kavitha, MS Shahabuddin, K Vinaya, CSA Kumar, ... Bioorganic & medicinal chemistry 17 (6), 2576-2584, 2009 | 113 | 2009 |
RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance RR Somasagara, SM Spencer, K Tripathi, DW Clark, C Mani, ... Oncogene 36 (48), 6680-6690, 2017 | 66 | 2017 |
Extract of Vernonia condensata, Inhibits Tumor Progression and Improves Survival of Tumor-allograft Bearing Mouse E Thomas, V Gopalakrishnan, RR Somasagara, B Choudhary, ... Scientific reports 6 (1), 23255, 2016 | 63 | 2016 |
Novel levamisole derivative induces extrinsic pathway of apoptosis in cancer cells and inhibits tumor progression in mice M Hegde, SS Karki, E Thomas, S Kumar, K Panjamurthy, SR Ranganatha, ... Public Library of Science 7 (9), e43632, 2012 | 63 | 2012 |
Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress … M M Derry, R R Somasagara, K Raina, S Kumar, J Gomez, M Patel, ... Current cancer drug targets 14 (4), 323-336, 2014 | 41 | 2014 |
Targeting MYC dependence by metabolic inhibitors in cancer HS Sabnis, RR Somasagara, KD Bunting Genes 8 (4), 114, 2017 | 39 | 2017 |
Bitter melon juice targets molecular mechanisms underlying gemcitabine resistance in pancreatic cancer cells RR Somasagara, G Deep, S Shrotriya, M Patel, C Agarwal, R Agarwal International journal of oncology 46 (4), 1849-1857, 2015 | 34 | 2015 |
Synthesis and identification of a new class of antileukemic agents containing 2-(arylcarboxamide)-(S)-6-amino-4, 5, 6, 7-tetrahydrobenzo [d] thiazole DS Prasanna, CV Kavitha, K Vinaya, SR Ranganatha, SC Raghavan, ... European journal of medicinal chemistry 45 (11), 5331-5336, 2010 | 29 | 2010 |
Rad6 upregulation promotes stem cell-like characteristics and platinum resistance in ovarian cancer RR Somasagara, K Tripathi, SM Spencer, DW Clark, R Barnett, ... Biochemical and biophysical research communications 469 (3), 449-455, 2016 | 28 | 2016 |
Detection and evaluation of estrogen DNA‐adducts and their carcinogenic effects in cultured human cells using biotinylated estradiol K Tripathi, C Mani, RR Somasagara, DW Clark, V Ananthapur, K Vinaya, ... Molecular carcinogenesis 56 (3), 1010-1020, 2017 | 25 | 2017 |
Synthesis and antiproliferative activity of substituted diazaspiro hydantoins: a structure–activity relationship study AK CS, SBB Prasad, K Vinaya, S Chandrappa, NR Thimmegowda, ... Investigational new drugs 27, 131-139, 2009 | 24 | 2009 |
Targeted therapy of human leukemia xenografts in immunodeficient zebrafish RR Somasagara, X Huang, C Xu, J Haider, JS Serody, PM Armistead, ... Scientific reports 11 (1), 5715, 2021 | 21 | 2021 |
Synthesis and identification of a new class of (S)-2,6-diamino-4,5,6,7-tetrahydrobenzo[d]thiazole derivatives as potent antileukemic agents DS Prasanna, CV Kavitha, B Raghava, K Vinaya, SR Ranganatha, ... Investigational new drugs 28, 454-465, 2010 | 14 | 2010 |
Synthesis and cytotoxic evaluation of novel 2-(4-(2,2,2-trifluoroethoxy)-3-methylpyridin-2-ylthio)-1H-benzo[d]imidazole derivatives SR Ranganatha, CV Kavitha, K Vinaya, DS Prasanna, S Chandrappa, ... Archives of pharmacal research 32, 1335-1343, 2009 | 14 | 2009 |
Evaluation of in vivo wound-healing potential of 2-[4-(2, 4-dimethoxy-benzoyl)-phenoxy]-1-[4-(3-piperidin-4-yl-propyl)-piperidin-1-yl]-ethanone derivatives K Vinaya, HR Naika, CSA Kumar, SBB Prasad, S Chandrappa, ... European journal of medicinal chemistry 44 (8), 3158-3165, 2009 | 10 | 2009 |
Synthesis of medicinally important N-trimethylene dipiperidine sulfonamides and carboxamides containing a substituted benzophenone moiety-an antibacterial agents MK Vinaya, HN Raja Naika, CKS Ananda Kumar, SB Benaka Prasad, ... Letters in Drug Design & Discovery 5 (4), 250-260, 2008 | 8 | 2008 |
Hedgehog/GLI1 Transcriptionally Regulates FANCD2 in Ovarian Tumor Cells: Its Inhibition Induces HR-Deficiency and Synergistic Lethality with PARP Inhibition. C Mani, K Tripathi, S Chaudhary, RR Somasagara, RP Rocconi, C Crasto, ... Neoplasia 23 (9), 1002-1015, 2021 | 7 | 2021 |