Obg and membrane depolarization are part of a microbial bet-hedging strategy that leads to antibiotic tolerance N Verstraeten, WJ Knapen, CI Kint, V Liebens, B Van den Bergh, ... Molecular cell 59 (1), 9-21, 2015 | 306 | 2015 |
Therapeutic nanoreactors: combining chemistry and biology in a novel triblock copolymer drug delivery system A Ranquin, W Versées, W Meier, J Steyaert, P Van Gelder Nano letters 5 (11), 2220-2224, 2005 | 247 | 2005 |
The universally conserved prokaryotic GTPases N Verstraeten, M Fauvart, W Versées, J Michiels Microbiology and Molecular Biology Reviews 75 (3), 507-542, 2011 | 222 | 2011 |
Fructose-1, 6-bisphosphate couples glycolytic flux to activation of Ras K Peeters, F Van Leemputte, B Fischer, BM Bonini, H Quezada, ... Nature communications 8 (1), 922, 2017 | 192 | 2017 |
Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts G Guaitoli, F Raimondi, BK Gilsbach, Y Gómez-Llorente, E Deyaert, ... Proceedings of the National Academy of Sciences 113 (30), E4357-E4366, 2016 | 158 | 2016 |
Characterization of Phenylpyruvate Decarboxylase, Involved in Auxin Production of Azospirillum brasilense S Spaepen, W Versées, D Gocke, M Pohl, J Steyaert, J Vanderleyden Journal of Bacteriology 189 (21), 7626-7633, 2007 | 153 | 2007 |
Catalysis by nucleoside hydrolases W Versées, J Steyaert Current Opinion in Structural Biology 13 (6), 731-738, 2003 | 139 | 2003 |
Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax W Versées, K Decanniere, R Pelle, J Depoorter, E Brosens, DW Parkin, ... Journal of molecular biology 307 (5), 1363-1379, 2001 | 126 | 2001 |
ELP3 controls active zone morphology by acetylating the ELKS family member Bruchpilot K Miśkiewicz, LE Jose, A Bento-Abreu, M Fislage, I Taes, J Kasprowicz, ... Neuron 72 (5), 776-788, 2011 | 107 | 2011 |
Leaving group activation by aromatic stacking: an alternative to general acid catalysis W Versees, S Loverix, A Vandemeulebroucke, P Geerlings, J Steyaert Journal of molecular biology 338 (1), 1-6, 2004 | 104 | 2004 |
Assessment of stability, toxicity and immunogenicity of new polymeric nanoreactors for use in enzyme replacement therapy of MNGIE C De Vocht, A Ranquin, R Willaert, JA Van Ginderachter, T Vanhaecke, ... Journal of controlled release 137 (3), 246-254, 2009 | 96 | 2009 |
Characterization of two homologous 2′-O-methyltransferases showing different specificities for their tRNA substrates J Somme, B Van Laer, M Roovers, J Steyaert, W Versées, L Droogmans Rna 20 (8), 1257-1271, 2014 | 86 | 2014 |
Elongator, a conserved multitasking complex? W Versées, S De Groeve, M Van Lijsebettens Molecular microbiology 76 (5), 1065-1069, 2010 | 69 | 2010 |
A homologue of the Parkinson’s disease-associated protein LRRK2 undergoes a monomer-dimer transition during GTP turnover E Deyaert, L Wauters, G Guaitoli, A Konijnenberg, M Leemans, ... Nature communications 8 (1), 1008, 2017 | 67 | 2017 |
Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax W Versées, K Decanniere, E Van Holsbeke, N Devroede, J Steyaert Journal of Biological Chemistry 277 (18), 15938-15946, 2002 | 67 | 2002 |
Skywalker-TBC1D24 has a lipid-binding pocket mutated in epilepsy and required for synaptic function B Fischer, K Lüthy, J Paesmans, C De Koninck, I Maes, J Swerts, ... Nature structural & molecular biology 23 (11), 965-973, 2016 | 61 | 2016 |
Crystal structures of the conserved tRNA-modifying enzyme GidA: implications for its interaction with MnmE and substrate S Meyer, A Scrima, W Versées, A Wittinghofer Journal of molecular biology 380 (3), 532-547, 2008 | 59 | 2008 |
Substrate Recognition and Activity Regulation of the Escherichia coli mRNA Endonuclease MazF*♦ V Zorzini, A Mernik, J Lah, YGJ Sterckx, N De Jonge, A Garcia-Pino, ... Journal of Biological Chemistry 291 (21), 10950-10960, 2016 | 52 | 2016 |
G-domain dimerization orchestrates the tRNA wobble modification reaction in the MnmE/GidA complex S Meyer, A Wittinghofer, W Versées Journal of molecular biology 392 (4), 910-922, 2009 | 52 | 2009 |
Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis W Versées, J Barlow, J Steyaert Journal of molecular biology 359 (2), 331-346, 2006 | 52 | 2006 |