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Harrison Brand
Harrison Brand
Assistant Professor at Harvard Medical School, Massachusetts General Hospital, & Broad Institute
在 mgh.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
The mutational constraint spectrum quantified from variation in 141,456 humans
KJ Karczewski, LC Francioli, G Tiao, BB Cummings, J Alföldi, Q Wang, ...
Nature 581 (7809), 434-443, 2020
8264*2020
Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism
FK Satterstrom, JA Kosmicki, J Wang, MS Breen, S De Rubeis, JY An, ...
Cell 180 (3), 568-584. e23, 2020
17542020
A structural variation reference for medical and population genetics
RL Collins, H Brand, KJ Karczewski, X Zhao, J Alföldi, LC Francioli, ...
Nature 581 (7809), 444-451, 2020
798*2020
Multi-platform discovery of haplotype-resolved structural variation in human genomes
MJP Chaisson, AD Sanders, X Zhao, A Malhotra, D Porubsky, T Rausch, ...
Nature communications 10 (1), 1784, 2019
7612019
Low incidence of off-target mutations in individual CRISPR-Cas9 and TALEN targeted human stem cell clones detected by whole-genome sequencing
A Veres, BS Gosis, Q Ding, R Collins, A Ragavendran, H Brand, S Erdin, ...
Cell stem cell 15 (1), 27-30, 2014
6342014
Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9
PK Mandal, LMR Ferreira, R Collins, TB Meissner, CL Boutwell, M Friesen, ...
Cell stem cell 15 (5), 643-652, 2014
6002014
High-coverage whole-genome sequencing of the expanded 1000 Genomes Project cohort including 602 trios
M Byrska-Bishop, US Evani, X Zhao, AO Basile, HJ Abel, AA Regier, ...
Cell 185 (18), 3426-3440. e19, 2022
4592022
Haplotype-resolved diverse human genomes and integrated analysis of structural variation
P Ebert, PA Audano, Q Zhu, B Rodriguez-Martin, D Porubsky, MJ Bonder, ...
Science 372 (6537), eabf7117, 2021
4592021
CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors
A Sugathan, M Biagioli, C Golzio, S Erdin, I Blumenthal, P Manavalan, ...
Proceedings of the National Academy of Sciences 111 (42), E4468-E4477, 2014
3452014
The genomic landscape of balanced cytogenetic abnormalities associated with human congenital anomalies
C Redin, H Brand, RL Collins, T Kammin, E Mitchell, JC Hodge, ...
Nature genetics 49 (1), 36-45, 2017
3182017
An analytical framework for whole-genome sequence association studies and its implications for autism spectrum disorder
DM Werling, H Brand, JY An, MR Stone, L Zhu, JT Glessner, RL Collins, ...
Nature genetics 50 (5), 727-736, 2018
2832018
Genome-wide de novo risk score implicates promoter variation in autism spectrum disorder
JY An, K Lin, L Zhu, DM Werling, S Dong, H Brand, HZ Wang, X Zhao, ...
Science 362 (6420), eaat6576, 2018
2782018
Rare coding variation provides insight into the genetic architecture and phenotypic context of autism
JM Fu, FK Satterstrom, M Peng, H Brand, RL Collins, S Dong, B Wamsley, ...
Nature genetics 54 (9), 1320-1331, 2022
241*2022
Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly
T Aneichyk, WT Hendriks, R Yadav, D Shin, D Gao, CA Vaine, RL Collins, ...
Cell 172 (5), 897-909, 2018
2062018
Mutations in DCHS1 cause mitral valve prolapse
R Durst, K Sauls, DS Peal, A Devlaming, K Toomer, M Leyne, M Salani, ...
Nature 525 (7567), 109-113, 2015
2022015
Defining the diverse spectrum of inversions, complex structural variation, and chromothripsis in the morbid human genome
RL Collins, H Brand, CE Redin, C Hanscom, C Antolik, MR Stone, ...
Genome biology 18, 1-21, 2017
1972017
SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome
ND Shaw, H Brand, ZA Kupchinsky, H Bengani, L Plummer, TI Jones, ...
Nature genetics 49 (2), 238-248, 2017
1692017
A cross-disorder dosage sensitivity map of the human genome
RL Collins, JT Glessner, E Porcu, M Lepamets, R Brandon, C Lauricella, ...
Cell 185 (16), 3041-3055. e25, 2022
1632022
Loss of δ-catenin function in severe autism
TN Turner, K Sharma, EC Oh, YP Liu, RL Collins, MX Sosa, DR Auer, ...
Nature 520 (7545), 51-56, 2015
1632015
Genome Aggregation Database C, Neale BM, Daly MJ, MacArthur DG (2020) The mutational constraint spectrum quantified from variation in 141,456 humans
KJ Karczewski, LC Francioli, G Tiao, BB Cummings, J Alfoldi, Q Wang, ...
Nature 581 (7809), 434-443, 0
118
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