| CDKL5 protein substitution therapy rescues neurological phenotypes of a mouse model of CDKL5 disorder S Trazzi, M De Franceschi, C Fuchs, S Bastianini, R Viggiano, L Lupori, ... Human molecular genetics 27 (9), 1572-1592, 2018 | 63 | 2018 |
| Heterozygous CDKL5 knockout female mice are a valuable animal model for CDKL5 disorder C Fuchs, L Gennaccaro, S Trazzi, S Bastianini, S Bettini, VL Martire, ... Neural Plasticity 2018 (1), 9726950, 2018 | 59 | 2018 |
| Functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder are rescued by a TrkB agonist E Ren, V Roncacé, S Trazzi, C Fuchs, G Medici, L Gennaccaro, M Loi, ... Frontiers in Cellular Neuroscience 13, 169, 2019 | 38 | 2019 |
| Inhibition of microglia overactivation restores neuronal survival in a mouse model of CDKL5 deficiency disorder G Galvani, N Mottolese, L Gennaccaro, M Loi, G Medici, M Tassinari, ... Journal of Neuroinflammation 18, 1-21, 2021 | 32 | 2021 |
| CDKL5 deficiency predisposes neurons to cell death through the deregulation of SMAD3 signaling C Fuchs, G Medici, S Trazzi, L Gennaccaro, G Galvani, C Berteotti, E Ren, ... Brain Pathology 29 (5), 658-674, 2019 | 28 | 2019 |
| DNA structure directs positioning of the mitochondrial genome packaging protein Abf2p A Chakraborty, S Lyonnais, F Battistini, A Hospital, G Medici, R Prohens, ... Nucleic Acids Research 45 (2), 951-967, 2017 | 28 | 2017 |
| Increased DNA damage and apoptosis in CDKL5-deficient neurons M Loi, S Trazzi, C Fuchs, G Galvani, G Medici, L Gennaccaro, M Tassinari, ... Molecular neurobiology 57, 2244-2262, 2020 | 25 | 2020 |
| Age-related cognitive and motor decline in a mouse model of CDKL5 deficiency disorder is associated with increased neuronal senescence and death L Gennaccaro, C Fuchs, M Loi, R Pizzo, S Alvente, C Berteotti, L Lupori, ... Aging and disease 12 (3), 764, 2021 | 24 | 2021 |
| Luteolin treatment ameliorates brain development and behavioral performance in a mouse model of CDKL5 deficiency disorder M Tassinari, N Mottolese, G Galvani, D Ferrara, L Gennaccaro, M Loi, ... International Journal of Molecular Sciences 23 (15), 8719, 2022 | 20 | 2022 |
| A GABAB receptor antagonist rescues functional and structural impairments in the perirhinal cortex of a mouse model of CDKL5 deficiency disorder L Gennaccaro, C Fuchs, M Loi, V Roncacè, S Trazzi, Y Ait-Bali, G Galvani, ... Neurobiology of Disease 153, 105304, 2021 | 16 | 2021 |
| Treatment with a GSK-3β/HDAC Dual Inhibitor Restores Neuronal Survival and Maturation in an In Vitro and In Vivo Model of CDKL5 Deficiency Disorder M Loi, L Gennaccaro, C Fuchs, S Trazzi, G Medici, G Galvani, N Mottolese, ... International Journal of Molecular Sciences 22 (11), 5950, 2021 | 16 | 2021 |
| Pharmacotherapy with sertraline rescues brain development and behavior in a mouse model of CDKL5 deficiency disorder C Fuchs, L Gennaccaro, E Ren, G Galvani, S Trazzi, G Medici, M Loi, ... Neuropharmacology 167, 107746, 2020 | 16 | 2020 |
| Expression of a secretable, cell-penetrating CDKL5 protein enhances the efficacy of gene therapy for CDKL5 deficiency disorder G Medici, M Tassinari, G Galvani, S Bastianini, L Gennaccaro, M Loi, ... Neurotherapeutics 19 (6), 1886-1904, 2022 | 8 | 2022 |
| Voluntary running improves behavioral and structural abnormalities in a mouse model of CDKL5 deficiency disorder N Mottolese, B Uguagliati, M Tassinari, CB Cerchier, M Loi, G Candini, ... Biomolecules 13 (9), 1396, 2023 | 5 | 2023 |
| Early-onset brain alterations during postnatal development in a mouse model of CDKL5 deficiency disorder M Tassinari, B Uguagliati, S Trazzi, CB Cerchier, OV Cavina, N Mottolese, ... Neurobiology of Disease 182, 106146, 2023 | 5 | 2023 |
| Cardiac functional and structural abnormalities in a mouse model of CDKL5 deficiency disorder M Loi, S Bastianini, G Candini, N Rizzardi, G Medici, V Papa, ... International Journal of Molecular Sciences 24 (6), 5552, 2023 | 5 | 2023 |
| Treatment with FRAX486 rescues neurobehavioral and metabolic alterations in a female mouse model of CDKL5 deficiency disorder C Fuchs, L Cosentino, C Urbinati, MC Talamo, G Medici, MC Quattrini, ... CNS Neuroscience & Therapeutics 28 (11), 1718-1732, 2022 | 5 | 2022 |
| Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5 G Matteoli, S Alvente, S Bastianini, C Berteotti, E Ciani, E Cinelli, ... Journal of Sleep Research, e14295, 2024 | 1 | 2024 |
| Postnatal Sensory Experience and Barrel Cortex Alterations Anticipate Autistic Traits in a Mouse Model of Cdkl5 Deficiency Disorder A Raspanti, R Pizzo, A Gurgone, C Giraudo, G Sagona, A Macioce, ... bioRxiv, 2024.12. 20.629347, 2024 | 1 | 2024 |
| Effects of a ciliary neurotrophic factor (CNTF) small-molecule peptide mimetic in an in vitro and in vivo model of CDKL5 deficiency disorder N Mottolese, M Loi, S Trazzi, M Tassinari, B Uguagliati, G Candini, K Iqbal, ... Journal of Neurodevelopmental Disorders 16 (1), 65, 2024 | | 2024 |
Sébastien LyonnaisCEMIPAI CNRS UAR 3725 Montpellier在 cemipai.cnrs.fr 的电子邮件经过验证
Sébastien LyonnaisCEMIPAI CNRS UAR 3725 Montpellier在 cemipai.cnrs.fr 的电子邮件经过验证
Maria SolàMolecular Biology Institute of Barcelona, CSIC在 ibmb.csic.es 的电子邮件经过验证