Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions EE Swinstead, TB Miranda, V Paakinaho, S Baek, I Goldstein, M Hawkins, ... Cell 165 (3), 593-605, 2016 | 297 | 2016 |
Glucocorticoid receptor activates poised FKBP51 locus through long-distance interactions V Paakinaho, H Makkonen, T Jääskeläinen, JJ Palvimo Molecular Endocrinology 24 (3), 511-525, 2010 | 148 | 2010 |
Single-molecule analysis of steroid receptor and cofactor action in living cells V Paakinaho, DM Presman, DA Ball, TA Johnson, RL Schiltz, P Levitt, ... Nature Communications 8, 15896, 2017 | 136 | 2017 |
Pioneer factors and ATP‐dependent chromatin remodeling factors interact dynamically: A new perspective EE Swinstead, V Paakinaho, DM Presman, GL Hager BioEssays 38 (11), 1150-1157, 2016 | 112 | 2016 |
Long-range activation of FKBP51 transcription by the androgen receptor via distal intronic enhancers H Makkonen, M Kauhanen, V Paakinaho, T Jääskeläinen, JJ Palvimo Nucleic acids research 37 (12), 4135-4148, 2009 | 111 | 2009 |
Global SUMOylation on active chromatin is an acute heat stress response restricting transcription EA Niskanen, M Malinen, P Sutinen, S Toropainen, V Paakinaho, ... Genome Biology 16 (1), 1-19, 2015 | 107 | 2015 |
Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response I Goldstein, S Baek, DM Presman, V Paakinaho, EE Swinstead, GL Hager Genome Research 27 (3), 427-439, 2016 | 106 | 2016 |
SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor V Paakinaho, S Kaikkonen, H Makkonen, V Benes, JJ Palvimo Nucleic Acids Research 42 (3), 1575-1592, 2014 | 94 | 2014 |
Quantifying transcription factor binding dynamics at the single-molecule level in live cells DM Presman, DA Ball, V Paakinaho, JB Grimm, LD Lavis, TS Karpova, ... Methods 123, 76-88, 2017 | 90 | 2017 |
An intrinsically disordered region-mediated confinement state contributes to the dynamics and function of transcription factors DA Garcia, TA Johnson, DM Presman, G Fettweis, K Wagh, L Rinaldi, ... Molecular Cell 81 (7), 1484-1498. e6, 2021 | 86 | 2021 |
Synergistic gene expression during the acute phase response is characterized by transcription factor assisted loading I Goldstein, V Paakinaho, S Baek, MH Sung, GL Hager Nature Communications 8 (1), 1849, 2017 | 77 | 2017 |
Power-law behavior of transcription factor dynamics at the single-molecule level implies a continuum affinity model DA Garcia, G Fettweis, DM Presman, V Paakinaho, C Jarzynski, ... Nucleic Acids Research 49 (12), 6605-6620, 2021 | 73 | 2021 |
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile K Dendoncker, S Timmermans, J Vandewalle, M Eggermont, ... Proceedings of the National Academy of Sciences 116 (26), 12942-12951, 2019 | 58 | 2019 |
Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome V Paakinaho, TA Johnson, DM Presman, GL Hager Genome research 29 (8), 1223-1234, 2019 | 57 | 2019 |
Dynamic SUMOylation is linked to the activity cycles of androgen receptor in the cell nucleus M Rytinki, S Kaikkonen, P Sutinen, V Paakinaho, V Rahkama, JJ Palvimo Molecular and cellular biology 32 (20), 4195-4205, 2012 | 51 | 2012 |
Genome-wide binding potential and regulatory activity of the glucocorticoid receptor’s monomeric and dimeric forms TA Johnson, V Paakinaho, S Kim, GL Hager, DM Presman Nature communications 12 (1), 1987, 2021 | 45 | 2021 |
Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis J Vandewalle, S Timmermans, V Paakinaho, L Vancraeynest, L Dewyse, ... Cell Metabolism 33 (9), 1763-1776. e5, 2021 | 34 | 2021 |
Meta-analysis of Chromatin Programming by Steroid Receptors V Paakinaho, EE Swinstead, DM Presman, L Grøntved, GL Hager Cell Reports 28 (13), 3523-3534. e2, 2019 | 33 | 2019 |
Prostaglandin 15d-PGJ2 Inhibits Androgen Receptor Signaling in Prostate Cancer Cells S Kaikkonen, V Paakinaho, P Sutinen, AL Levonen, JJ Palvimo Molecular Endocrinology 27 (2), 212-223, 2013 | 31 | 2013 |
SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites V Paakinaho, JK Lempiäinen, G Sigismondo, EA Niskanen, M Malinen, ... Nucleic Acids Research 49 (4), 1951-1971, 2021 | 25 | 2021 |