| CRISPResso2 provides accurate and rapid genome editing sequence analysis K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ... Nature biotechnology 37 (3), 224-226, 2019 | 1006 | 2019 |
| Engineered CRISPR–Cas12a variants with increased activities and improved targeting ranges for gene, epigenetic and base editing BP Kleinstiver, AA Sousa, RT Walton, YE Tak, JY Hsu, K Clement, ... Nature biotechnology 37 (3), 276-282, 2019 | 550 | 2019 |
| Predictable and precise template-free CRISPR editing of pathogenic variants MW Shen, M Arbab, JY Hsu, D Worstell, SJ Culbertson, O Krabbe, ... Nature 563 (7733), 646-651, 2018 | 517 | 2018 |
| Nuclear RNA-seq of single neurons reveals molecular signatures of activation B Lacar, SB Linker, BN Jaeger, SR Krishnaswami, JJ Barron, MJE Kelder, ... Nature communications 7 (1), 11022, 2016 | 431 | 2016 |
| Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM H Chen, L Albergante, JY Hsu, CA Lareau, G Lo Bosco, J Guan, S Zhou, ... Nature communications 10 (1), 1-14, 2019 | 232 | 2019 |
| A dual-deaminase CRISPR base editor enables concurrent adenine and cytosine editing J Grünewald, R Zhou, CA Lareau, SP Garcia, S Iyer, BR Miller, ... Nature Biotechnology 38 (7), 861-864, 2020 | 222 | 2020 |
| Inducible and multiplex gene regulation using CRISPR–Cpf1-based transcription factors YE Tak, BP Kleinstiver, JK Nuñez, JY Hsu, JE Horng, J Gong, ... Nature methods 14 (12), 1163-1166, 2017 | 206 | 2017 |
| CRISPR prime editing with ribonucleoprotein complexes in zebrafish and primary human cells K Petri, W Zhang, J Ma, A Schmidts, H Lee, JE Horng, DY Kim, IC Kurt, ... Nature biotechnology 40 (2), 189-193, 2022 | 150 | 2022 |
| PrimeDesign software for rapid and simplified design of prime editing guide RNAs JY Hsu, J Grünewald, R Szalay, J Shih, AV Anzalone, KC Lam, MW Shen, ... Nature Communications 12 (1), 1034, 2021 | 144 | 2021 |
| Nup153 interacts with Sox2 to enable bimodal gene regulation and maintenance of neural progenitor cells T Toda, JY Hsu, SB Linker, L Hu, ST Schafer, J Mertens, FV Jacinto, ... Cell stem cell 21 (5), 618-634. e7, 2017 | 118 | 2017 |
| Transcription factor competition at the γ-globin promoters controls hemoglobin switching N Liu, S Xu, Q Yao, Q Zhu, Y Kai, JY Hsu, P Sakon, L Pinello, GC Yuan, ... Nature genetics 53 (4), 511-520, 2021 | 67 | 2021 |
| Response to “Unexpected mutations after CRISPR–Cas9 editing in vivo” CA Lareau, K Clement, JY Hsu, V Pattanayak, JK Joung, MJ Aryee, ... Nature methods 15 (4), 238-239, 2018 | 49* | 2018 |
| Tuning gene activity by inducible and targeted regulation of gene expression in minimal bacterial cells AM Mariscal, S Kakizawa, JY Hsu, K Tanaka, L González-González, ... ACS synthetic biology 7 (6), 1538-1552, 2018 | 36 | 2018 |
| CRISPR-SURF: discovering regulatory elements by deconvolution of CRISPR tiling screen data JY Hsu, CP Fulco, MA Cole, MC Canver, D Pellin, F Sher, R Farouni, ... Nature methods 15 (12), 992-993, 2018 | 34 | 2018 |
| Scalable characterization of the PAM requirements of CRISPR–Cas enzymes using HT-PAMDA RT Walton, JY Hsu, JK Joung, BP Kleinstiver Nature protocols 16 (3), 1511-1547, 2021 | 32 | 2021 |
| Technologies and computational analysis strategies for CRISPR applications K Clement, JY Hsu, MC Canver, JK Joung, L Pinello Molecular cell 79 (1), 11-29, 2020 | 31 | 2020 |
| Systems and methods for predicting repair outcomes in genetic engineering MW Shen, JYT HSU, M Arbab, DK Gifford, DR Liu, RI Sherwood | 12 | 2020 |
| Human-specific regulation of neural maturation identified by cross-primate transcriptomics SB Linker, I Narvaiza, JY Hsu, M Wang, F Qiu, APD Mendes, R Oefner, ... Current Biology 32 (22), 4797-4807. e5, 2022 | 11 | 2022 |
| Room Temperature Isothermal Colorimetric Padlock Probe Rolling Circle Amplification for Viral DNA and RNA Detection W Huang, J Ting, M Fang, H Hsu, J Su, T Misaki, D Chan, J Yang, TY Yeh, ... BioRxiv, 2020.06. 12.128876, 2020 | 11 | 2020 |
| Accurate and rapid analysis of genome editing data from nucleases and base editors with CRISPResso2 K Clement, H Rees, MC Canver, JM Gehrke, R Farouni, JY Hsu, MA Cole, ... Nature biotechnology 37 (3), 224, 2019 | 11 | 2019 |
