Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril K Maeda, I Ieiri, K Yasuda, A Fujino, H Fujiwara, K Otsubo, M Hirano, ... Clinical Pharmacology & Therapeutics 79 (5), 427-439, 2006 | 235 | 2006 |
Increasing systemic exposure of methotrexate by active efflux mediated by multidrug resistance-associated protein 3 (mrp3/abcc3) Y Kitamura, M Hirouchi, H Kusuhara, JD Schuetz, Y Sugiyama Journal of Pharmacology and Experimental Therapeutics 327 (2), 465-473, 2008 | 73 | 2008 |
Basolateral Efflux Mediated by Multidrug Resistance-Associated Protein 3 (Mrp3/Abcc3) Facilitates Intestinal Absorption of Folates in Mouse Y Kitamura, H Kusuhara, Y Sugiyama Pharmaceutical research 27, 665-672, 2010 | 41 | 2010 |
Prorocentrol, a Polyoxy Linear Carbon Chain Compound Isolated from the Toxic Dinoflagellate Prorocentrum hoffmannianum K Sugahara, Y Kitamura, M Murata, M Satake, K Tachibana The Journal of Organic Chemistry 76 (9), 3131-3138, 2011 | 31 | 2011 |
Functional characterization of multidrug resistance-associated protein 3 (mrp3/abcc3) in the basolateral efflux of glucuronide conjugates in the mouse small intestine Y Kitamura, H Kusuhara, Y Sugiyama Journal of Pharmacology and Experimental Therapeutics 332 (2), 659-666, 2010 | 29 | 2010 |
Design, Synthesis, and Structure− Activity Relationship Studies of Novel 2, 4, 6-Trisubstituted-5-pyrimidinecarboxylic Acids as Peroxisome Proliferator-Activated Receptor γ … S Seto, K Okada, K Kiyota, S Isogai, M Iwago, T Shinozaki, Y Kitamura, ... Journal of medicinal chemistry 53 (13), 5012-5024, 2010 | 27 | 2010 |
A proposal of a pharmacokinetic/pharmacodynamic (PK/PD) index map for selecting an optimal PK/PD index from conventional indices (AUC/MIC, Cmax/MIC, and TAM) for antibiotics Y Kitamura, K Yoshida, M Kusama, Y Sugiyama Drug metabolism and pharmacokinetics 29 (6), 455-462, 2014 | 26 | 2014 |
Relationship between the urinary excretion mechanisms of drugs and their physicochemical properties S Ito, H Ando, A Ose, Y Kitamura, T Ando, H Kusuhara, Y Sugiyama Journal of Pharmaceutical Sciences 102 (9), 3294-3301, 2013 | 26 | 2013 |
Modest effect of impaired P-glycoprotein on the plasma concentrations of fexofenadine, quinidine, and loperamide following oral administration in collies Y Kitamura, H Koto, S Matsuura, T Kawabata, H Tsuchiya, H Kusuhara, ... Drug Metabolism and Disposition 36 (5), 807-810, 2008 | 25 | 2008 |
Hepatic uptake in the dog: comparison of uptake in hepatocytes and human embryonic kidney cells expressing dog organic anion-transporting polypeptide 1B4 AJ Wilby, K Maeda, PF Courtney, Y Debori, PJH Webborn, Y Kitamura, ... Drug metabolism and disposition 39 (12), 2361-2369, 2011 | 23 | 2011 |
Quantitative analysis of the ABCG2 c. 421C> A polymorphism effect on in vivo transport activity of breast cancer resistance protein (BCRP) using an intestinal absorption model Y Tanaka, Y Kitamura, K Maeda, Y Sugiyama Journal of Pharmaceutical Sciences 104 (9), 3039-3048, 2015 | 21 | 2015 |
Prediction of human bioavailability from human oral administration data and animal pharmacokinetic data without data from intravenous administration of drugs in humans H Imawaka, K Ito, Y Kitamura, K Sugiyama, Y Sugiyama Pharmaceutical research 26 (8), 1881-1889, 2009 | 16 | 2009 |
Characterization of a highly sensitive and selective novel trapping reagent, stable isotope labeled glutathione ethyl ester, for the detection of reactive metabolites T Yamaoka, Y Kitamura Journal of Pharmacological and Toxicological Methods 76, 83-95, 2015 | 12 | 2015 |
Explication of definitional description and empirical use of fraction of orally administered drugs absorbed from the intestine (Fa) and intestinal availability (Fg): effect of … Y Tanaka, Y Kitamura, K Maeda, Y Sugiyama Journal of pharmaceutical sciences 105 (2), 431-442, 2016 | 10 | 2016 |