A highly conserved cryptic epitope in the receptor binding domains of SARS-CoV-2 and SARS-CoV M Yuan, NC Wu, X Zhu, CCD Lee, RTY So, H Lv, CKP Mok, IA Wilson Science 368 (6491), 630-633, 2020 | 1563 | 2020 |
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model TF Rogers, F Zhao, D Huang, N Beutler, A Burns, W He, O Limbo, C Smith, ... Science 369 (6506), 956-963, 2020 | 1350 | 2020 |
Structural basis of a shared antibody response to SARS-CoV-2 M Yuan, H Liu, NC Wu, CCD Lee, X Zhu, F Zhao, D Huang, W Yu, Y Hua, ... Science 369 (6507), 1119-1123, 2020 | 567 | 2020 |
Cross-reactive antibody response between SARS-CoV-2 and SARS-CoV infections H Lv, NC Wu, OTY Tsang, M Yuan, RAPM Perera, WS Leung, RTY So, ... Cell reports 31 (9), 2020 | 451 | 2020 |
Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020 RAPM Perera, CKP Mok, OTY Tsang, H Lv, RLW Ko, NC Wu, M Yuan, ... Eurosurveillance 25 (16), 2020 | 382 | 2020 |
Structural and functional ramifications of antigenic drift in recent SARS-CoV-2 variants M Yuan, D Huang, CCD Lee, NC Wu, AM Jackson, X Zhu, H Liu, L Peng, ... Science 373 (6556), 818-823, 2021 | 358 | 2021 |
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape PA Koenig, H Das, H Liu, BM Kümmerer, FN Gohr, LM Jenster, ... Science 371 (6530), eabe6230, 2021 | 339 | 2021 |
A therapeutic non-self-reactive SARS-CoV-2 antibody protects from lung pathology in a COVID-19 hamster model J Kreye, SM Reincke, HC Kornau, E Sánchez-Sendin, VM Corman, H Liu, ... Cell 183 (4), 1058-1069. e19, 2020 | 331 | 2020 |
Cross-neutralization of a SARS-CoV-2 antibody to a functionally conserved site is mediated by avidity H Liu, NC Wu, M Yuan, S Bangaru, JL Torres, TG Caniels, ... Immunity 53 (6), 1272-1280. e5, 2020 | 211 | 2020 |
Recognition of the SARS-CoV-2 receptor binding domain by neutralizing antibodies M Yuan, H Liu, NC Wu, IA Wilson Biochemical and biophysical research communications 538, 192-203, 2021 | 180 | 2021 |
An alternative binding mode of IGHV3-53 antibodies to the SARS-CoV-2 receptor binding domain NC Wu, M Yuan, H Liu, CCD Lee, X Zhu, S Bangaru, JL Torres, ... Cell reports 33 (3), 108274, 2020 | 155 | 2020 |
Broadly neutralizing antibodies target the coronavirus fusion peptide C Dacon, C Tucker, L Peng, CCD Lee, TH Lin, M Yuan, Y Cong, L Wang, ... Science 377 (6607), 728-735, 2022 | 139 | 2022 |
A human antibody reveals a conserved site on beta-coronavirus spike proteins and confers protection against SARS-CoV-2 infection P Zhou, M Yuan, G Song, N Beutler, N Shaabani, D Huang, W He, X Zhu, ... Science Translational Medicine 14 (637), eabi9215, 2022 | 136 | 2022 |
Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern H Cho, KK Gonzales-Wartz, D Huang, M Yuan, M Peterson, J Liang, ... Science Translational Medicine 13 (616), eabj5413, 2021 | 86 | 2021 |
SARS-CoV-2 Beta variant infection elicits potent lineage-specific and cross-reactive antibodies SM Reincke, M Yuan, HC Kornau, VM Corman, S van Hoof, ... Science 375 (6582), 782-787, 2022 | 71 | 2022 |
A natural mutation between SARS-CoV-2 and SARS-CoV determines neutralization by a cross-reactive antibody NC Wu, M Yuan, S Bangaru, D Huang, X Zhu, CCD Lee, HL Turner, ... PLoS pathogens 16 (12), e1009089, 2020 | 66 | 2020 |
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates CA Cottrell, J Van Schooten, CA Bowman, M Yuan, D Oyen, M Shin, ... PLoS pathogens 16 (8), e1008753, 2020 | 64 | 2020 |
Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis W Zhong, L Cui, BC Goh, Q Cai, P Ho, YH Chionh, M Yuan, A El Sahili, ... Nature Communications 8 (1), 2017 | 61 | 2017 |
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease P Zhou, G Song, H Liu, M Yuan, W He, N Beutler, X Zhu, VT Longping, ... Immunity 56 (3), 669-686. e7, 2023 | 60 | 2023 |
An allostatic mechanism for M2 pyruvate kinase as an amino-acid sensor M Yuan, IW McNae, Y Chen, EA Blackburn, MA Wear, PAM Michels, ... Biochemical Journal 475 (10), 1821-1837, 2018 | 59 | 2018 |