Strategies to improve the EPR effect: A mechanistic perspective and clinical translation M Ikeda-Imafuku, LLW Wang, D Rodrigues, S Shaha, Z Zhao, S Mitragotri Journal of Controlled Release 345, 512-536, 2022 | 109 | 2022 |
S-Nitrosated human serum albumin dimer as novel nano-EPR enhancer applied to macromolecular anti-tumor drugs such as micelles and liposomes R Kinoshita, Y Ishima, M Ikeda, U Kragh-Hansen, J Fang, H Nakamura, ... Journal of Controlled Release 217, 1-9, 2015 | 58 | 2015 |
Quantitative determination of polysulfide in albumins, plasma proteins and biological fluid samples using a novel combined assays approach M Ikeda, Y Ishima, A Shibata, VTG Chuang, T Sawa, H Ihara, H Watanabe, ... Analytica chimica acta 969, 18-25, 2017 | 43 | 2017 |
Human serum albumin hydropersulfide is a potent reactive oxygen species scavenger in oxidative stress conditions such as chronic kidney disease A Shibata, Y Ishima, M Ikeda, H Sato, T Imafuku, VTG Chuang, Y Ouchi, ... Biochemical and biophysical research communications 479 (3), 578-583, 2016 | 33 | 2016 |
A novel S-sulfhydrated human serum albumin preparation suppresses melanin synthesis M Ikeda, Y Ishima, R Kinoshita, VTG Chuang, N Tasaka, N Matsuo, ... Redox Biology 14, 354-360, 2018 | 28 | 2018 |
Involvement of SAPK/JNK signaling pathway in copper enhanced zinc-induced neuronal cell death KI Tanaka, M Shimoda, M Kasai, M Ikeda, Y Ishima, M Kawahara Toxicological Sciences 169 (1), 293-302, 2019 | 26 | 2019 |
Poly‐S‐nitrosated human albumin enhances the antitumor and antimetastasis effect of bevacizumab, partly by inhibiting autophagy through the generation of nitric … Y Ishima, A Inoue, J Fang, R Kinoshita, M Ikeda, H Watanabe, H Maeda, ... Cancer Science 106 (2), 194-200, 2015 | 25 | 2015 |
Distribution of polysulfide in human biological fluids and their association with amylase and sperm activities M Ikeda, Y Ishima, VTG Chuang, M Sakai, H Osafune, H Ando, T Shimizu, ... Molecules 24 (9), 1689, 2019 | 19 | 2019 |
Dual therapeutic effects of an albumin-based nitric oxide donor on 2 experimental models of chronic kidney disease S Oshiro, Y Ishima, H Maeda, N Honda, J Bi, R Kinoshita, M Ikeda, Y Iwao, ... Journal of Pharmaceutical Sciences 107 (3), 848-855, 2018 | 17 | 2018 |
Thioredoxin-albumin fusion protein prevents urban aerosol-induced lung injury via suppressing oxidative stress-related neutrophil extracellular trap formation K Tanaka, M Kubota, M Shimoda, T Hayase, M Miyaguchi, N Kobayashi, ... Environmental Pollution 268, 115787, 2021 | 12 | 2021 |
Extracellular matrix degrading enzyme with stroma-targeting peptides enhance the penetration of liposomes into tumors M Ikeda-Imafuku, Y Gao, S Shaha, LLW Wang, KS Park, M Nakajima, ... Journal of Controlled Release 352, 1093-1103, 2022 | 11 | 2022 |
Encapsulation of an Antioxidant in Redox-Sensitive Self-Assembled Albumin Nanoparticles for the Treatment of Hepatitis K Yasuda, H Maeda, R Kinoshita, Y Minayoshi, Y Mizuta, Y Nakamura, ... ACS nano 17 (17), 16668-16681, 2023 | 8 | 2023 |
8‐Prenylnaringenin tissue distribution and pharmacokinetics in mice and its binding to human serum albumin and cellular uptake in human embryonic kidney cells Y Tanaka, H Okuyama, M Nishikawa, S Ikushiro, M Ikeda, Y Ishima, ... Food Science & Nutrition 10 (4), 1070-1080, 2022 | 8 | 2022 |
Apoptosis induction of poly-S-nitrosated human serum albumin in resistant solid tumor under hypoxia can be restored by phosphodiesterase 5 inhibition M Ikeda, Y Ishima, VTG Chuang, T Ikeda, R Kinoshita, H Watanabe, ... Nitric Oxide 69, 28-34, 2017 | 7 | 2017 |
Development of edaravone ionic liquids and their application for the treatment of cerebral ischemia/reperfusion injury T Fukuta, M Ikeda-Imafuku, Y Iwao Molecular Pharmaceutics 20 (6), 3115-3126, 2023 | 6 | 2023 |
One-step pharmaceutical preparation of PEG-modified exosomes encapsulating anti-cancer drugs by a high-pressure homogenization technique T Fukuta, M Ikeda-Imafuku, S Kodama, J Kuse, K Matsui, Y Iwao Pharmaceuticals 16 (1), 108, 2023 | 5 | 2023 |
Human hair keratin responds to oxidative stress via reactive sulfur and supersulfides T Hirai, M Ikeda-Imafuku, N Tasaka, VTG Chuang, M Xian, T Ishida, ... Advances in Redox Research 10, 100091, 2024 | 3 | 2024 |
A polymer‐based systemic hemostat for managing uncontrolled bleeding Y Gao, M Ikeda‐Imafuku, Z Zhao, M Joshi, S Mitragotri Bioengineering & Translational Medicine 8 (3), e10516, 2023 | 3 | 2023 |
Methoxylation of methyl 3alpha, 7alpha-dihydroxychol-4-en-24-oate and its 3beta-epimer. A contribution to chenodeoxycholic acid biogenesis. M Ikeda, K Yamasaki Steroids 32 (1), 85-93, 1978 | 3 | 1978 |
Effectiveness of albumin-fused thioredoxin against 6-hydroxydopamine-induced neurotoxicity in vitro O Sakakibara, M Shimoda, G Yamamoto, Y Higashi, M Ikeda-Imafuku, ... International Journal of Molecular Sciences 24 (11), 9758, 2023 | 2 | 2023 |