Phosphoinositide 3-Kinase (PI3K) reactive oxygen species (ROS)-activated prodrug in combination with anthracycline impairs pi3k signaling, increases DNA damage response and … R Mishra, L Yuan, H Patel, AS Karve, H Zhu, A White, S Alanazi, P Desai, ... International Journal of Molecular Sciences 22 (4), 2088, 2021 | 20 | 2021 |
mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors CS Lewis, HE Thomas, MA Orr‐Asman, LC Green, RE Boody, K Matiash, ... Journal of thrombosis and haemostasis 17 (1), 169-182, 2019 | 15 | 2019 |
A review of approaches to potentiate the activity of temozolomide against glioblastoma to overcome resistance AS Karve, JM Desai, SN Gadgil, N Dave, TM Wise-Draper, GA Gudelsky, ... International Journal of Molecular Sciences 25 (6), 3217, 2024 | 11 | 2024 |
Potentiation of temozolomide activity against glioblastoma cells by aromatase inhibitor letrozole AS Karve, JM Desai, N Dave, TM Wise-Draper, GA Gudelsky, TN Phoenix, ... Cancer chemotherapy and pharmacology 90 (4), 345-356, 2022 | 8 | 2022 |
Brain pharmacokinetics and metabolism of the AMP-activated protein kinase selective inhibitor SBI-0206965, an investigational agent for the treatment of glioblastoma JM Desai, AS Karve, GA Gudelsky, MV Gawali, W Seibel, L Sallans, ... Investigational new drugs 40 (5), 944-952, 2022 | 7 | 2022 |
A first-in-class, humanized antibody targeting alternatively spliced tissue factor: preclinical evaluation in an orthotopic model of pancreatic ductal adenocarcinoma CS Lewis, A Karve, K Matiash, T Stone, J Li, JK Wang, HH Versteeg, ... Frontiers in Oncology 11, 691685, 2021 | 7 | 2021 |
Reuse of molecules for glioblastoma therapy A Koehler, A Karve, P Desai, J Arbiser, DR Plas, X Qi, RD Read, ... Pharmaceuticals 14 (2), 99, 2021 | 5 | 2021 |
Pharmacokinetics of levetiracetam seizure prophylaxis in severe traumatic brain injury SS Harlan, CD Philpott, SP Keegan, ME Droege, AS Karve, B Foreman, ... Annals of Pharmacotherapy 58 (7), 705-714, 2024 | 2 | 2024 |
A Phase 0/I Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination with Standard Therapy in Recurrent High-Grade Gliomas PB Desai, AS Karve, M Zawit, P Arora, N Dave, J Awosika, N Li, ... Clinical Cancer Research 30 (10), 2068-2077, 2024 | 2 | 2024 |
GABA (A) Receptor Activation Drives GABARAP–Nix Mediated Autophagy to Radiation-Sensitize Primary and Brain-Metastatic Lung Adenocarcinoma Tumors D Bhattacharya, R Barrile, DK Toukam, VS Gawali, L Kallay, T Ahmed, ... Cancers 16 (18), 3167, 2024 | 1 | 2024 |
Bzd-1 as a chemosensitizer of cancer DP Krummel, S Sengupta, JM Cook, T Ahmed, A Karve, L Kallay, P Desai, ... US Patent App. 18/564,894, 2024 | | 2024 |
GABA (A) receptor activation drives GABARAP-Nix mediated autophagy to radiosensitize primary and metastatic lung adenocarcinoma tumors D Bhattacharya, R Barrile, DK Toukam, VS Gawali, L Kallay, T Ahmed, ... Cancer Research 84 (6_Supplement), 703-703, 2024 | | 2024 |
Translational research to facilitate development of novel therapeutic combinations of letrozole for the treatment of glioblastoma AS Karve, BB Gabani, SN Gadgil, SP Kulkarni, GA Gudelsky, PB Desai Cancer Research 84 (6_Supplement), 2119-2119, 2024 | | 2024 |
1286: IMPACT OF AUGMENTED RENAL CLEARANCE ON VANCOMYCIN IN CRITICALLY ILL TRAUMA PATIENTS T Rice, M Droege, C Philpott, J Courter, P Desai, N Harger, N Ernst, ... Critical Care Medicine 51 (1), 642, 2023 | | 2023 |
ACTIVATING AN ION CHANNEL PROMOTES RADIATION-SENSITIZING IMMUNE-DRIVEN ANTI-TUMOR ACTIVITY DK Toukam, D Bhattacharya, V Gawali, L Kallay, A Karve, P Desai, ... NEURO-ONCOLOGY 24, 246-247, 2022 | | 2022 |
EXTH-101. MECHANISTIC INSIGHTS INTO CYTOTOXIC EFFECTS OF LETROZOLE AGAINST GLIOBLASTOMA CELLS A Karve, J Desai, N Dave, T Phoenix, G Gudelsky, D Plas, B Dasgupta, ... Neuro-Oncology 24 (Suppl 7), vii233, 2022 | | 2022 |
EXTH-99. SYSTEMIC AND BRAIN PHARMACOKINETICS OF A GABAA RECEPTOR AGONIST, AMLAL-101, AS AN INVESTIGATIONAL THERAPEUTIC FOR THE … A Karve, T Ahmed, J Desai, D Bhattacharya, DK Toukam, S Gadgil, ... Neuro-Oncology 24 (Supplement_7), vii232-vii233, 2022 | | 2022 |
RBIO-02. ACTIVATION OF GABAA RECEPTORS WITH A NON-TOXIC, BRAIN PENETRANT SMALL MOLECULE SENSITIZES LUNG ADENOCARCINOMA … D Bhattacharya, R Barille, DK Toukam, V Gawali, L Kallay, T Ahmed, ... Neuro-Oncology 24 (Supplement_7), vii247-vii247, 2022 | | 2022 |
Translational Research to Facilitate Development of Novel Therapeutics for the Treatment of Glioblastoma AS Karve University of Cincinnati, 2022 | | 2022 |
EXTH-52. SYSTEMIC AND BRAIN PHARMACOKINETICS OF THE AMP-ACTIVATED PROTEIN KINASE SELECTIVE INHIBITOR SBI-0206965 AS A POTENTIAL THERAPEUTIC AGENT FOR THE TREATMENT OF … J Desai, M Gawali, A Karve, G Gudelsky, L Sallans, B Dasgupta, W Seibel, ... Neuro-Oncology 23 (Supplement_6), vi175-vi175, 2021 | | 2021 |