Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion DH Yu, CK Qu, O Henegariu, X Lu, GS Feng Journal of Biological Chemistry 273 (33), 21125-21131, 1998 | 513 | 1998 |
Protein tyrosine phosphatases in the JAK/STAT pathway D Xu, CK Qu Frontiers in bioscience: a journal and virtual library 13, 4925, 2008 | 392 | 2008 |
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation WM Yu, X Liu, J Shen, O Jovanovic, EE Pohl, SL Gerson, T Finkel, ... Cell stem cell 12 (1), 62-74, 2013 | 350 | 2013 |
Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment L Dong, WM Yu, H Zheng, ML Loh, ST Bunting, M Pauly, G Huang, ... Nature 539 (7628), 304-308, 2016 | 256 | 2016 |
The PLAG1-GDH1 axis promotes anoikis resistance and tumor metastasis through CamKK2-AMPK signaling in LKB1-deficient lung cancer L Jin, J Chun, C Pan, A Kumar, G Zhang, Y Ha, D Li, GN Alesi, Y Kang, ... Molecular cell 69 (1), 87-99. e7, 2018 | 244 | 2018 |
The SHP-2 tyrosine phosphatase: signaling mechanisms and biological functions CK Qu Cell research 10 (4), 279-288, 2000 | 222 | 2000 |
A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development CK Qu, ZQ Shi, R Shen, FY Tsai, SH Orkin, GS Feng Molecular and cellular biology, 1997 | 204 | 1997 |
Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells DW Seo, H Li, CK Qu, J Oh, YS Kim, T Diaz, B Wei, JW Han, ... Journal of Biological Chemistry 281 (6), 3711-3721, 2006 | 188 | 2006 |
Role of the SHP-2 tyrosine phosphatase in cytokine-induced signaling and cellular response CK Qu Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1592 (3), 297-301, 2002 | 177 | 2002 |
Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells CK Qu, WM Yu, B Azzarelli, S Cooper, HE Broxmeyer, GS Feng Molecular and cellular biology, 1998 | 167 | 1998 |
Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development CK Qu, S Nguyen, J Chen, GS Feng Blood, The Journal of the American Society of Hematology 97 (4), 911-914, 2001 | 157 | 2001 |
Receptor‐stimulated oxidation of SHP‐2 promotes T‐cell adhesion through SLP‐76–ADAP J Kwon, CK Qu, JS Maeng, R Falahati, C Lee, MS Williams The EMBO journal 24 (13), 2331-2341, 2005 | 151 | 2005 |
Factor XII and uPAR upregulate neutrophil functions to influence wound healing EX Stavrou, C Fang, KL Bane, AT Long, C Naudin, E Kucukal, A Gandhi, ... The Journal of clinical investigation 128 (3), 944-959, 2018 | 135 | 2018 |
Genetic evidence that Shp-2 tyrosine phosphatase is a signal enhancer of the epidermal growth factor receptor in mammals CK Qu, WM Yu, B Azzarelli, GS Feng Proceedings of the National Academy of Sciences 96 (15), 8528-8533, 1999 | 121 | 1999 |
Deficiency of MIP/MTMR14 phosphatase induces a muscle disorder by disrupting Ca2+ homeostasis J Shen, WM Yu, M Brotto, JA Scherman, C Guo, C Stoddard, TM Nosek, ... Nature cell biology 11 (6), 769-776, 2009 | 118 | 2009 |
Non–lineage/stage-restricted effects of a gain-of-function mutation in tyrosine phosphatase Ptpn11 (Shp2) on malignant transformation of hematopoietic cells D Xu, X Liu, WM Yu, HJ Meyerson, C Guo, SL Gerson, CK Qu Journal of Experimental Medicine 208 (10), 1977-1988, 2011 | 117 | 2011 |
Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses CH Kim, CK Qu, G Hangoc, S Cooper, N Anzai, GS Feng, HE Broxmeyer The Journal of experimental medicine 190 (5), 681-690, 1999 | 110 | 1999 |
MAST1 drives cisplatin resistance in human cancers by rewiring cRaf-independent MEK activation L Jin, J Chun, C Pan, D Li, R Lin, GN Alesi, X Wang, HB Kang, L Song, ... Cancer cell 34 (2), 315-330. e7, 2018 | 109 | 2018 |
Shp-2 has a positive regulatory role in ES cell differentiation and proliferation CK Qu, GS Feng Oncogene 17 (4), 433-439, 1998 | 101 | 1998 |
Regulation of the dephosphorylation of Stat6: participation of Tyr-713 in the interleukin-4 receptor α, the tyrosine phosphatase SHP-1, and the proteasome EM Hanson, H Dickensheets, CK Qu, RP Donnelly, AD Keegan Journal of Biological Chemistry 278 (6), 3903-3911, 2003 | 98 | 2003 |