Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-β pathways C Alarcón, AI Zaromytidou, Q Xi, S Gao, J Yu, S Fujisawa, A Barlas, ... Cell 139 (4), 757-769, 2009 | 833 | 2009 |
WW and SH3 domains, two different scaffolds to recognize proline‐rich ligands MJ Macias, S Wiesner, M Sudol FEBS letters 513 (1), 30-37, 2002 | 613 | 2002 |
Structure of the WW domain of a kinase-associated protein complexed with a proline-rich peptide MJ Macias, M Hyvönen, E Baraldi, J Schultz, M Sudol, M Saraste, ... Nature Publishing Group 382 (6592), 646-649, 1996 | 567 | 1996 |
Automated NOESY interpretation with ambiguous distance restraints: the refined NMR solution structure of the pleckstrin homology domain from β-spectrin M Nilges, MJ Macias, SI O’Donoghue, H Oschkinat Journal of molecular biology 269 (3), 408-422, 1997 | 533 | 1997 |
Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-β signaling S Gao, C Alarcón, G Sapkota, S Rahman, PY Chen, N Goerner, ... Molecular cell 36 (3), 457-468, 2009 | 416 | 2009 |
Structure of the binding site for inositol phosphates in a PH domain. M Hyvönen, MJ Macias, M Nilges, H Oschkinat, M Saraste, M Wilmanns The EMBO journal 14 (19), 4676-4685, 1995 | 414 | 1995 |
Structural determinants of Smad function in TGF-β signaling MJ Macias, P Martin-Malpartida, J Massagué Trends in biochemical sciences 40 (6), 296-308, 2015 | 409 | 2015 |
Structure of the dsRNA binding domain of E. coli RNase III. A Kharrat, MJ Macias, TJ Gibson, M Nilges, A Pastore The EMBO journal 14 (14), 3572-3584, 1995 | 346 | 1995 |
Specific interactions between the syntrophin PDZ domain and voltage-gated sodium channels J Schultz, U Hoffmuüller, G Krause, J Ashurst, MJ Macias, P Schmieder, ... Nature Structural & Molecular Biology 5 (1), 19-24, 1998 | 336 | 1998 |
Structure of the pleckstrin homology domain from β-spectrin MJ Macias, A Musacchio, H Ponstingl, M Nilges, M Saraste, H Oschkinat Nature 369 (6482), 675-677, 1994 | 301 | 1994 |
A Smad action turnover switch operated by WW domain readers of a phosphoserine code E Aragón, N Goerner, AI Zaromytidou, Q Xi, A Escobedo, J Massagué, ... Genes & development 25 (12), 1275-1288, 2011 | 287 | 2011 |
Structural analysis of WW domains and design of a WW prototype MJ Macias, V Gervais, C Civera, H Oschkinat Nature Structural & Molecular Biology 7 (5), 375-379, 2000 | 270 | 2000 |
The three-dimensional structure of the HRDC domain and implications for the Werner and Bloom syndrome proteins Z Liu, MJ Macias, MJ Bottomley, G Stier, JP Linge, M Nilges, P Bork, ... Structure 7 (12), 1557-1566, 1999 | 183 | 1999 |
ADP-ribose–derived nuclear ATP synthesis by NUDIX5 is required for chromatin remodeling RHG Wright, A Lioutas, F Le Dily, D Soronellas, A Pohl, J Bonet, AS Nacht, ... Science 352 (6290), 1221-1225, 2016 | 172 | 2016 |
Solution structures of the YAP65 WW domain and the variant L30 K in complex with the peptides GTPPPPYTVG, N-(n-octyl)-GPPPY and PLPPY and the application of peptide libraries … JR Pires, F Taha-Nejad, F Toepert, T Ast, U Hoffmüller, ... Journal of molecular biology 314 (5), 1147-1156, 2001 | 143 | 2001 |
Ultrafast folding of WW domains without structured aromatic clusters in the denatured state N Ferguson, CM Johnson, M Macias, H Oschkinat, A Fersht Proceedings of the National Academy of Sciences 98 (23), 13002-13007, 2001 | 131 | 2001 |
Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways E Aragón, N Goerner, Q Xi, T Gomes, S Gao, J Massagué, MJ Macias Structure 20 (10), 1726-1736, 2012 | 120 | 2012 |
Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors P Martin-Malpartida, M Batet, Z Kaczmarska, R Freier, T Gomes, E Aragón, ... Nature Communications 8 (1), 2070, 2017 | 103 | 2017 |
Solution structure and ligand recognition of the WW domain pair of the yeast splicing factor Prp40 S Wiesner, G Stier, M Sattler, MJ Macias Journal of molecular biology 324 (4), 807-822, 2002 | 98 | 2002 |
Structural basis for distinct roles of SMAD2 and SMAD3 in FOXH1 pioneer-directed TGF-β signaling E Aragón, Q Wang, Y Zou, SM Morgani, L Ruiz, Z Kaczmarska, J Su, ... Genes & development 33 (21-22), 1506-1524, 2019 | 77 | 2019 |