| The emerging mechanisms of isoform-specific PI3K signalling B Vanhaesebroeck, J Guillermet-Guibert, M Graupera, B Bilanges Nature reviews Molecular cell biology 11 (5), 329-341, 2010 | 2089 | 2010 |
| Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration M Graupera, J Guillermet-Guibert, LC Foukas, LK Phng, RJ Cain, ... Nature 453 (7195), 662-666, 2008 | 624 | 2008 |
| The p110β isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110γ J Guillermet-Guibert, K Bjorklof, A Salpekar, C Gonella, F Ramadani, ... Proceedings of the National Academy of Sciences 105 (24), 8292-8297, 2008 | 441 | 2008 |
| Molecular signaling of somatostatin receptors H Lahlou, J Guillermet, M Hortala, F Vernejoul, S Pyronnet, C Bousquet, ... Annals of the New York Academy of Sciences 1014 (1), 121-131, 2004 | 195 | 2004 |
| Somatostatin receptor subtype 2 sensitizes human pancreatic cancer cells to death ligand-induced apoptosis J Guillermet, N Saint-Laurent, P Rochaix, O Cuvillier, T Levade, ... Proceedings of the National Academy of Sciences 100 (1), 155-160, 2003 | 193 | 2003 |
| Dominant role of the p110β isoform of PI3K over p110α in energy homeostasis regulation by POMC and AgRP neurons H Al-Qassab, MA Smith, EE Irvine, J Guillermet-Guibert, M Claret, ... Cell metabolism 10 (5), 343-354, 2009 | 180 | 2009 |
| Targeting the sphingolipid metabolism to defeat pancreatic cancer cell resistance to the chemotherapeutic gemcitabine drug J Guillermet-Guibert, L Davenne, D Pchejetski, N Saint-Laurent, ... Molecular cancer therapeutics 8 (4), 809-820, 2009 | 180 | 2009 |
| Deletion of the p110β isoform of phosphoinositide 3-kinase in platelets reveals its central role in Akt activation and thrombus formation in vitro and in vivo V Martin, J Guillermet-Guibert, G Chicanne, C Cabou, M Jandrot-Perrus, ... Blood, The Journal of the American Society of Hematology 115 (10), 2008-2013, 2010 | 159 | 2010 |
| Hypoxia induces VEGF-C expression in metastatic tumor cells via a HIF-1α-independent translation-mediated mechanism F Morfoisse, A Kuchnio, C Frainay, A Gomez-Brouchet, MB Delisle, ... Cell reports 6 (1), 155-167, 2014 | 154 | 2014 |
| Targeting PI3K signaling in combination cancer therapy E Pons-Tostivint, B Thibault, J Guillermet-Guibert Trends in cancer 3 (6), 454-469, 2017 | 146 | 2017 |
| Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α R Baer, C Cintas, M Dufresne, S Cassant-Sourdy, N Schönhuber, ... Genes & development 28 (23), 2621-2635, 2014 | 124 | 2014 |
| Physiology of somatostatin receptors J Guillermet-Guibert, H Lahlou, P Cordelier, C Bousquet, S Pyronnet, ... J Endocrinol Invest 28 (11), 5-9, 2005 | 110 | 2005 |
| Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway C Bousquet, J Guillermet‐Guibert, N Saint‐Laurent, E Archer‐Lahlou, ... The EMBO journal 25 (17), 3943-3954, 2006 | 108 | 2006 |
| Laser-assisted 3D bioprinting of exocrine pancreas spheroid models for cancer initiation study D Hakobyan, C Medina, N Dusserre, ML Stachowicz, C Handschin, ... Biofabrication 12 (3), 035001, 2020 | 102 | 2020 |
| Implication of PI3K/Akt pathway in pancreatic cancer: When PI3K isoforms matter? R Baer, C Cintas, N Therville, J Guillermet-Guibert Advances in biological regulation 59, 19-35, 2015 | 94 | 2015 |
| Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor IM Berenjeno, J Guillermet-Guibert, W Pearce, A Gray, S Fleming, ... Biochemical Journal 442 (1), 151-159, 2012 | 88 | 2012 |
| Somatostatin analogs: does pharmacology impact antitumor efficacy? M Chalabi, C Duluc, P Caron, D Vezzosi, J Guillermet-Guibert, S Pyronnet, ... Trends in Endocrinology & Metabolism 25 (3), 115-127, 2014 | 86 | 2014 |
| Regulation and roles of PI3Kβ, a major actor in platelet signaling and functions MP Gratacap, J Guillermet-Guibert, V Martin, G Chicanne, H Tronchère, ... Advances in enzyme regulation 51 (1), 106-116, 2011 | 81 | 2011 |
| Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis A Soler, H Serra, W Pearce, A Angulo, J Guillermet-Guibert, LS Friedman, ... Journal of Experimental Medicine 210 (10), 1937-1945, 2013 | 77 | 2013 |
| Acinar-to-ductal metaplasia induced by transforming growth factor beta facilitates KRASG12D-driven pancreatic tumorigenesis N Chuvin, DF Vincent, RM Pommier, LB Alcaraz, J Gout, C Caligaris, ... Cellular and molecular gastroenterology and hepatology 4 (2), 263-282, 2017 | 74 | 2017 |
Bart VanhaesebroeckUCL Cancer Institute, University College London, London UK在 ucl.ac.uk 的电子邮件经过验证
