| Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9 D Paquet, D Kwart, A Chen, A Sproul, S Jacob, S Teo, KM Olsen, A Gregg, ... Nature 533 (7601), 125-129, 2016 | 1024 | 2016 |
| Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1 E Kiskinis, J Sandoe, LA Williams, GL Boulting, R Moccia, BJ Wainger, ... Cell stem cell 14 (6), 781-795, 2014 | 510 | 2014 |
| A viral strategy for targeting and manipulating interneurons across vertebrate species J Dimidschstein, Q Chen, R Tremblay, SL Rogers, GA Saldi, L Guo, Q Xu, ... Nature neuroscience 19 (12), 1743-1749, 2016 | 478 | 2016 |
| Directed differentiation of human pluripotent stem cells to microglia P Douvaras, B Sun, M Wang, I Kruglikov, G Lallos, M Zimmer, ... Stem cell reports 8 (6), 1516-1524, 2017 | 331 | 2017 |
| Differentiation of human embryonic stem cells to dopaminergic neurons in serum‐free suspension culture TC Schulz, SA Noggle, GM Palmarini, DA Weiler, IG Lyons, KA Pensa, ... Stem cells 22 (7), 1218-1238, 2004 | 317 | 2004 |
| Human embryonic stem cell lines derived from discarded embryos M Mitalipova, J Calhoun, S Shin, D Wininger, T Schulz, S Noggle, ... Stem cells 21 (5), 521-526, 2003 | 298 | 2003 |
| Nuclear genome transfer in human oocytes eliminates mitochondrial DNA variants D Paull, V Emmanuele, KA Weiss, N Treff, L Stewart, H Hua, M Zimmer, ... Nature 493 (7434), 632-637, 2013 | 287 | 2013 |
| Human oocytes reprogram somatic cells to a pluripotent state S Noggle, HL Fung, A Gore, H Martinez, KC Satriani, R Prosser, K Oum, ... Nature 478 (7367), 70-75, 2011 | 265 | 2011 |
| iPSC-derived dopamine neurons reveal differences between monozygotic twins discordant for Parkinson’s disease CM Woodard, BA Campos, SH Kuo, MJ Nirenberg, MW Nestor, M Zimmer, ... Cell reports 9 (4), 1173-1182, 2014 | 257 | 2014 |
| Long-term proliferation of human embryonic stem cell–derived neuroepithelial cells using defined adherent culture conditions S Shin, M Mitalipova, S Noggle, D Tibbitts, A Venable, R Rao, SL Stice Stem cells 24 (1), 125-138, 2006 | 250 | 2006 |
| Automated, high-throughput derivation, characterization and differentiation of induced pluripotent stem cells D Paull, A Sevilla, H Zhou, AK Hahn, H Kim, C Napolitano, A Tsankov, ... Nature methods 12 (9), 885-892, 2015 | 240 | 2015 |
| Quality control guidelines for clinical-grade human induced pluripotent stem cell lines S Sullivan, GN Stacey, C Akazawa, N Aoyama, R Baptista, P Bedford, ... Regenerative medicine 13 (7), 859-866, 2018 | 205 | 2018 |
| Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors AA Sproul, S Jacob, D Pre, SH Kim, MW Nestor, M Navarro-Sobrino, ... PloS one 9 (1), e84547, 2014 | 204 | 2014 |
| Contribution of human embryonic stem cells to mouse blastocysts D James, SA Noggle, T Swigut, AH Brivanlou Developmental biology 295 (1), 90-102, 2006 | 196 | 2006 |
| Directed neuronal differentiation of human embryonic stem cells TC Schulz, GM Palmarini, SA Noggle, DA Weiler, MM Mitalipova, ... BMC neuroscience 4, 1-13, 2003 | 194 | 2003 |
| Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ... Science advances 7 (2), eabb5398, 2021 | 175 | 2021 |
| CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer’s PSEN2 N141I neurons M Ortiz-Virumbrales, CL Moreno, I Kruglikov, P Marazuela, A Sproul, ... Acta neuropathologica communications 5, 1-20, 2017 | 152 | 2017 |
| Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide E Bieberich, S MacKinnon, J Silva, S Noggle, BG Condie The Journal of cell biology 162 (3), 469-479, 2003 | 140 | 2003 |
| A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs) D Prè, MW Nestor, AA Sproul, S Jacob, P Koppensteiner, ... PloS one 9 (7), e103418, 2014 | 127 | 2014 |
| Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ... Neuron 109 (2), 257-272. e14, 2021 | 123 | 2021 |
