Artemisinins: their growing importance in medicine S Krishna, L Bustamante, RK Haynes, HM Staines Trends in pharmacological sciences 29 (10), 520-527, 2008 | 460 | 2008 |
Artemisinins CJ Woodrow, RK Haynes, S Krishna Postgraduate medical journal 81 (952), 71-78, 2005 | 394 | 2005 |
A single amino acid residue can determine the sensitivity of SERCAs to artemisinins AC Uhlemann, A Cameron, U Eckstein-Ludwig, J Fischbarg, P Iserovich, ... Nature structural & molecular biology 12 (7), 628-629, 2005 | 351 | 2005 |
Artemisinins: mechanisms of action and potential for resistance S Krishna, AC Uhlemann, RK Haynes Drug Resistance Updates 7 (4-5), 233-244, 2004 | 347 | 2004 |
Artemisone—a highly active antimalarial drug of the artemisinin class RK Haynes, B Fugmann, J Stetter, K Rieckmann, HD Heilmann, HW Chan, ... Angewandte Chemie International Edition 45 (13), 2082-2088, 2006 | 320 | 2006 |
Possible modes of action of the artemisinin-type compounds PL Olliaro, RK Haynes, B Meunier, Y Yuthavong TRENDS in Parasitology 17 (3), 122-126, 2001 | 320 | 2001 |
From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements RK Haynes Current topics in medicinal chemistry 6 (5), 509-537, 2006 | 300 | 2006 |
From qinghao, marvelous herb of antiquity, to the antimalarial trioxane qinghaosu and some remarkable new chemistry RK Haynes, SC Vonwiller Accounts of chemical research 30 (2), 73-79, 1997 | 259 | 1997 |
Artemisinin and derivatives: the future for malaria treatment? RK Haynes Current opinion in infectious diseases 14 (6), 719-726, 2001 | 197 | 2001 |
Artemisinins Inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense In Vitro Growth YV Mishina, S Krishna, RK Haynes, JC Meade Antimicrobial agents and chemotherapy 51 (5), 1852-1854, 2007 | 190 | 2007 |
Artemisinins: activities and actions RK Haynes, S Krishna Microbes and infection 6 (14), 1339-1346, 2004 | 175 | 2004 |
Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance S Krishna, CJ Woodrow, HM Staines, RK Haynes, O Mercereau-Puijalon Trends in molecular medicine 12 (5), 200-205, 2006 | 157 | 2006 |
Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity RK Haynes, WY Ho, HW Chan, B Fugmann, J Stetter, SL Croft, L Vivas, ... Angewandte Chemie-International Edition 43 (11), 1381-1385, 2004 | 157 | 2004 |
The Fe2+‐Mediated Decomposition, PfATP6 Binding, and Antimalarial Activities of Artemisone and Other Artemisinins: The Unlikelihood of C‐Centered Radicals … RK Haynes, WC Chan, CM Lung, AC Uhlemann, U Eckstein, D Taramelli, ... ChemMedChem: Chemistry Enabling Drug Discovery 2 (10), 1480-1497, 2007 | 152 | 2007 |
Neurotoxic mode of action of artemisinin G Schmuck, E Roehrdanz, RK Haynes, R Kahl Antimicrobial agents and chemotherapy 46 (3), 821-827, 2002 | 150 | 2002 |
Highly enantioselective phenyl transfer to aryl aldehydes catalyzed by easily accessible chiral tertiary aminonaphthol JX Ji, J Wu, TTL Au-Yeung, CW Yip, RK Haynes, ASC Chan The Journal of Organic Chemistry 70 (3), 1093-1095, 2005 | 136 | 2005 |
First assessment in humans of the safety, tolerability, pharmacokinetics, and ex vivo pharmacodynamic antimalarial activity of the new artemisinin derivative artemisone J Nagelschmitz, B Voith, G Wensing, A Roemer, B Fugmann, RK Haynes, ... Antimicrobial agents and chemotherapy 52 (9), 3085-3091, 2008 | 127 | 2008 |
Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo L Vivas, L Rattray, LB Stewart, BL Robinson, B Fugmann, RK Haynes, ... Journal of antimicrobial chemotherapy 59 (4), 658-665, 2007 | 121 | 2007 |
The behaviour of qinghaosu (artemisinin) in the presence of heme iron (II) and (III) RK Haynes, SC Vonwiller Tetrahedron letters 37 (2), 253-256, 1996 | 119 | 1996 |
In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells A Dwivedi, A Mazumder, L Du Plessis, JL Du Preez, RK Haynes, ... Nanomedicine: Nanotechnology, Biology and Medicine 11 (8), 2041-2050, 2015 | 111 | 2015 |