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Richard Haynes
Richard Haynes
Professor, Senior Principal Research Fellow (Rural and Global Health) Rural Health Research
在 csu.edu.au 的电子邮件经过验证
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Artemisinins: their growing importance in medicine
S Krishna, L Bustamante, RK Haynes, HM Staines
Trends in pharmacological sciences 29 (10), 520-527, 2008
4602008
Artemisinins
CJ Woodrow, RK Haynes, S Krishna
Postgraduate medical journal 81 (952), 71-78, 2005
3942005
A single amino acid residue can determine the sensitivity of SERCAs to artemisinins
AC Uhlemann, A Cameron, U Eckstein-Ludwig, J Fischbarg, P Iserovich, ...
Nature structural & molecular biology 12 (7), 628-629, 2005
3512005
Artemisinins: mechanisms of action and potential for resistance
S Krishna, AC Uhlemann, RK Haynes
Drug Resistance Updates 7 (4-5), 233-244, 2004
3472004
Artemisone—a highly active antimalarial drug of the artemisinin class
RK Haynes, B Fugmann, J Stetter, K Rieckmann, HD Heilmann, HW Chan, ...
Angewandte Chemie International Edition 45 (13), 2082-2088, 2006
3202006
Possible modes of action of the artemisinin-type compounds
PL Olliaro, RK Haynes, B Meunier, Y Yuthavong
TRENDS in Parasitology 17 (3), 122-126, 2001
3202001
From artemisinin to new artemisinin antimalarials: biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements
RK Haynes
Current topics in medicinal chemistry 6 (5), 509-537, 2006
3002006
From qinghao, marvelous herb of antiquity, to the antimalarial trioxane qinghaosu and some remarkable new chemistry
RK Haynes, SC Vonwiller
Accounts of chemical research 30 (2), 73-79, 1997
2591997
Artemisinin and derivatives: the future for malaria treatment?
RK Haynes
Current opinion in infectious diseases 14 (6), 719-726, 2001
1972001
Artemisinins Inhibit Trypanosoma cruzi and Trypanosoma brucei rhodesiense In Vitro Growth
YV Mishina, S Krishna, RK Haynes, JC Meade
Antimicrobial agents and chemotherapy 51 (5), 1852-1854, 2007
1902007
Artemisinins: activities and actions
RK Haynes, S Krishna
Microbes and infection 6 (14), 1339-1346, 2004
1752004
Re-evaluation of how artemisinins work in light of emerging evidence of in vitro resistance
S Krishna, CJ Woodrow, HM Staines, RK Haynes, O Mercereau-Puijalon
Trends in molecular medicine 12 (5), 200-205, 2006
1572006
Highly antimalaria-active artemisinin derivatives: biological activity does not correlate with chemical reactivity
RK Haynes, WY Ho, HW Chan, B Fugmann, J Stetter, SL Croft, L Vivas, ...
Angewandte Chemie-International Edition 43 (11), 1381-1385, 2004
1572004
The Fe2+‐Mediated Decomposition, PfATP6 Binding, and Antimalarial Activities of Artemisone and Other Artemisinins: The Unlikelihood of C‐Centered Radicals …
RK Haynes, WC Chan, CM Lung, AC Uhlemann, U Eckstein, D Taramelli, ...
ChemMedChem: Chemistry Enabling Drug Discovery 2 (10), 1480-1497, 2007
1522007
Neurotoxic mode of action of artemisinin
G Schmuck, E Roehrdanz, RK Haynes, R Kahl
Antimicrobial agents and chemotherapy 46 (3), 821-827, 2002
1502002
Highly enantioselective phenyl transfer to aryl aldehydes catalyzed by easily accessible chiral tertiary aminonaphthol
JX Ji, J Wu, TTL Au-Yeung, CW Yip, RK Haynes, ASC Chan
The Journal of Organic Chemistry 70 (3), 1093-1095, 2005
1362005
First assessment in humans of the safety, tolerability, pharmacokinetics, and ex vivo pharmacodynamic antimalarial activity of the new artemisinin derivative artemisone
J Nagelschmitz, B Voith, G Wensing, A Roemer, B Fugmann, RK Haynes, ...
Antimicrobial agents and chemotherapy 52 (9), 3085-3091, 2008
1272008
Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo
L Vivas, L Rattray, LB Stewart, BL Robinson, B Fugmann, RK Haynes, ...
Journal of antimicrobial chemotherapy 59 (4), 658-665, 2007
1212007
The behaviour of qinghaosu (artemisinin) in the presence of heme iron (II) and (III)
RK Haynes, SC Vonwiller
Tetrahedron letters 37 (2), 253-256, 1996
1191996
In vitro anti-cancer effects of artemisone nano-vesicular formulations on melanoma cells
A Dwivedi, A Mazumder, L Du Plessis, JL Du Preez, RK Haynes, ...
Nanomedicine: Nanotechnology, Biology and Medicine 11 (8), 2041-2050, 2015
1112015
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