Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nature genetics 45 (12), 1452-1458, 2013 | 4402 | 2013 |
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2249 | 2019 |
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1605 | 2019 |
New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 971 | 2022 |
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ... Nature genetics 49 (9), 1373-1384, 2017 | 919 | 2017 |
α-Synuclein in blood and brain from familial Parkinson disease with SNCA locus triplication DW Miller, SM Hague, J Clarimon, M Baptista, K Gwinn-Hardy, ... Neurology 62 (10), 1835-1838, 2004 | 450 | 2004 |
Trading genes along the silk road: mtDNA sequences and the origin of central Asian populations D Comas, F Calafell, E Mateu, A Pérez-Lezaun, E Bosch, ... The American Journal of Human Genetics 63 (6), 1824-1838, 1998 | 441 | 1998 |
A novel GSK-3β inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo L Serenó, M Coma, M Rodriguez, P Sánchez-Ferrer, MB Sánchez, I Gich, ... Neurobiology of disease 35 (3), 359-367, 2009 | 417 | 2009 |
Frontotemporal dementia and its subtypes: a genome-wide association study R Ferrari, DG Hernandez, MA Nalls, JD Rohrer, A Ramasamy, JBJ Kwok, ... The Lancet Neurology 13 (7), 686-699, 2014 | 385 | 2014 |
European Alzheimer’s Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer’s Disease; Alzheimer’s Disease Genetic Consortium; Cohorts for Heart and Aging … JC Lambert, CA Ibrahim-Verbaas, D Harold, AC Naj, R Sims, ... Nat Genet 45 (12), 1452-1458, 2013 | 292 | 2013 |
A novel Alzheimer disease locus located near the gene encoding tau protein G Jun, CA Ibrahim-Verbaas, M Vronskaya, JC Lambert, J Chung, AC Naj, ... Molecular psychiatry 21 (1), 108-117, 2016 | 291 | 2016 |
Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP RJ Guerreiro, M Baquero, R Blesa, M Boada, JM Brás, MJ Bullido, ... Neurobiology of aging 31 (5), 725-731, 2010 | 252 | 2010 |
Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study R Guerreiro, OA Ross, C Kun-Rodrigues, DG Hernandez, T Orme, ... The Lancet Neurology 17 (1), 64-74, 2018 | 243 | 2018 |
Clinical and biomarker changes of Alzheimer's disease in adults with Down syndrome: a cross-sectional study J Fortea, E Vilaplana, M Carmona-Iragui, B Benejam, L Videla, I Barroeta, ... The Lancet 395 (10242), 1988-1997, 2020 | 231 | 2020 |
Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture R Chia, MS Sabir, S Bandres-Ciga, S Saez-Atienzar, RH Reynolds, ... Nature genetics 53 (3), 294-303, 2021 | 225 | 2021 |
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk Y Deming, F Filipello, F Cignarella, C Cantoni, S Hsu, R Mikesell, Z Li, ... Science translational medicine 11 (505), eaau2291, 2019 | 220 | 2019 |
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores I De Rojas, S Moreno-Grau, N Tesi, B Grenier-Boley, V Andrade, ... Nature communications 12 (1), 3417, 2021 | 186 | 2021 |
Confluence of α-synuclein, tau, and β-amyloid pathologies in dementia with Lewy bodies M Colom-Cadena, E Gelpi, S Charif, O Belbin, R Blesa, MJ Martí, ... Journal of Neuropathology & Experimental Neurology 72 (12), 1203-1212, 2013 | 185 | 2013 |
Sex-specific migration patterns in Central Asian populations, revealed by analysis of Y-chromosome short tandem repeats and mtDNA A Pérez-Lezaun, F Calafell, D Comas, E Mateu, E Bosch, ... The American Journal of Human Genetics 65 (1), 208-219, 1999 | 185 | 1999 |
Plasma and CSF biomarkers for the diagnosis of Alzheimer's disease in adults with Down syndrome: a cross-sectional study J Fortea, M Carmona-Iragui, B Benejam, S Fernández, L Videla, ... The Lancet Neurology 17 (10), 860-869, 2018 | 173 | 2018 |