| Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles X Bai, IS Fernandez, G McMullan, SHW Scheres elife 2, e00461, 2013 | 489 | 2013 |
| Computed structures of core eukaryotic protein complexes IR Humphreys, J Pei, M Baek, A Krishnakumar, I Anishchenko, ... Science 374 (6573), eabm4805, 2021 | 443 | 2021 |
| Structure of the mammalian ribosome-Sec61 complex to 3.4 Å resolution RM Voorhees, IS Fernández, SHW Scheres, RS Hegde Cell 157 (7), 1632-1643, 2014 | 385 | 2014 |
| Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine W Wong, X Bai, A Brown, IS Fernandez, E Hanssen, M Condron, YH Tan, ... Elife 3, e03080, 2014 | 376 | 2014 |
| Initiation of translation by cricket paralysis virus IRES requires its translocation in the ribosome IS Fernández, XC Bai, G Murshudov, SHW Scheres, V Ramakrishnan Cell 157 (4), 823-831, 2014 | 258 | 2014 |
| Ribosome-dependent activation of stringent control A Brown, IS Fernández, Y Gordiyenko, V Ramakrishnan Nature 534 (7606), 277-280, 2016 | 235 | 2016 |
| Elongation factor G bound to the ribosome in an intermediate state of translocation DS Tourigny, IS Fernández, AC Kelley, V Ramakrishnan Science 340 (6140), 1235490, 2013 | 228 | 2013 |
| Structural changes enable start codon recognition by the eukaryotic translation initiation complex T Hussain, JL Llácer, IS Fernández, A Munoz, P Martin-Marcos, CG Savva, ... Cell 159 (3), 597-607, 2014 | 214 | 2014 |
| Unusual base pairing during the decoding of a stop codon by the ribosome IS Fernández, CL Ng, AC Kelley, G Wu, YT Yu, V Ramakrishnan Nature 500 (7460), 107-110, 2013 | 207 | 2013 |
| Mefloquine targets the Plasmodium falciparum 80S ribosome to inhibit protein synthesis W Wong, XC Bai, BE Sleebs, T Triglia, A Brown, JK Thompson, ... Nature microbiology 2 (6), 1-9, 2017 | 190 | 2017 |
| Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation CP Lapointe, R Grosely, AG Johnson, J Wang, IS Fernández, JD Puglisi Proceedings of the National Academy of Sciences 118 (6), e2017715118, 2021 | 165 | 2021 |
| Molecular architecture of a eukaryotic translational initiation complex IS Fernández, XC Bai, T Hussain, AC Kelley, JR Lorsch, V Ramakrishnan, ... Science 342 (6160), 1240585, 2013 | 163 | 2013 |
| Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors IS Fernández, P Cuevas, J Angulo, P López-Navajas, ... Journal of Biological Chemistry 285 (15), 11714-11729, 2010 | 125 | 2010 |
| Structural basis of DNA targeting by a transposon-encoded CRISPR–Cas system TS Halpin-Healy, SE Klompe, SH Sternberg, IS Fernández Nature 577 (7789), 271-274, 2020 | 116 | 2020 |
| Structural characterization of ribosome recruitment and translocation by type IV IRES J Murray, CG Savva, BS Shin, TE Dever, V Ramakrishnan, IS Fernández Elife 5, e13567, 2016 | 111 | 2016 |
| Novel structural features in the GMC family of oxidoreductases revealed by the crystal structure of fungal aryl-alcohol oxidase IS Fernández, FJ Ruiz-Duenas, E Santillana, P Ferreira, MJ Martínez, ... Acta Crystallographica Section D: Biological Crystallography 65 (11), 1196-1205, 2009 | 110 | 2009 |
| The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle N Arnaudo, IS Fernández, SH McLaughlin, SY Peak-Chew, D Rhodes, ... Nature structural & molecular biology 20 (9), 1119-1121, 2013 | 99 | 2013 |
| The nonsense-mediated mRNA decay SMG-1 kinase is regulated by large-scale conformational changes controlled by SMG-8 E Arias-Palomo, A Yamashita, IS Fernández, R Núñez-Ramírez, Y Bamba, ... Genes & development 25 (2), 153-164, 2011 | 95 | 2011 |
| The ribosome triggers the stringent response by RelA via a highly distorted tRNA X Agirrezabala, IS Fernández, AC Kelley, DG Cartón, V Ramakrishnan, ... EMBO reports 14 (9), 811-816, 2013 | 80 | 2013 |
| eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining CP Lapointe, R Grosely, M Sokabe, C Alvarado, J Wang, E Montabana, ... Nature 607 (7917), 185-190, 2022 | 50 | 2022 |
Venki RamakrishnanMRC Laboratory of Molecular Biology, Cambridge, United Kingdom在 mrc-lmb.cam.ac.uk 的电子邮件经过验证
