Synthesis of novel 1, 3, 4-trisubstituted pyrazole derivatives and their evaluation as antitumor and antiangiogenic agents AH Abadi, AAH Eissa, GS Hassan Chemical and pharmaceutical bulletin 51 (7), 838-844, 2003 | 303 | 2003 |
Synthesis of 3-substituted-2-oxoindole analogues and their evaluation as kinase inhibitors, anticancer and antiangiogenic agents AH Abadi, SM Abou-Seri, DE Abdel-Rahman, C Klein, O Lozach, L Meijer European journal of medicinal chemistry 41 (3), 296-305, 2006 | 145 | 2006 |
Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling N Li, Y Xi, HN Tinsley, E Gurpinar, BD Gary, B Zhu, Y Li, X Chen, ... Molecular cancer therapeutics 12 (9), 1848-1859, 2013 | 133 | 2013 |
Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents AH Abadi, GH Hegazy, AA El-Zaher Bioorganic & medicinal chemistry 13 (20), 5759-5765, 2005 | 133 | 2005 |
Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors AH Abadi, TM Ibrahim, KM Abouzid, J Lehmann, HN Tinsley, BD Gary, ... Bioorganic & medicinal chemistry 17 (16), 5974-5982, 2009 | 131 | 2009 |
Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of … HN Tinsley, BD Gary, AB Keeton, W Zhang, AH Abadi, RC Reynolds, ... Molecular cancer therapeutics 8 (12), 3331-3340, 2009 | 116 | 2009 |
Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents RK Arafa, GH Hegazy, GA Piazza, AH Abadi European journal of medicinal chemistry 63, 826-832, 2013 | 94 | 2013 |
A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity JD Whitt, N Li, HN Tinsley, X Chen, W Zhang, Y Li, BD Gary, AB Keeton, ... Cancer prevention research 5 (6), 822-833, 2012 | 78 | 2012 |
Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach AH Abadi, DA Abouel-Ella, J Lehmann, HN Tinsley, BD Gary, GA Piazza, ... European journal of medicinal chemistry 45 (1), 90-97, 2010 | 71 | 2010 |
Synthesis and Antitumor Activity of Ethyl 2‐Substituted‐aminothiazole‐4‐carboxylate Analogs HI El‐Subbagh, AH Abadi, J Lehmann Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 1999 | 71 | 1999 |
Synthesis of 4-alkyl (aryl)-6-aryl-3-cyano-2 (1H)-pyridinones and their 2-imino isosteres as nonsteroidal cardiotonic agents A Abadi, O Al-Deeb, A Al-Afify, H El-Kashef Il Farmaco 54 (4), 195-201, 1999 | 67 | 1999 |
Synthesis and Antitumor Activity of Some New Substituted Quinolin‐4‐one and 1, 7‐Naphthyridin‐4‐one Analogs HI E.‐Subbagh, AH Abadi, LE Al‐Khawad, KA Al‐Rashood Archiv der Pharmazie: An International Journal Pharmaceutical and Medicinal …, 1999 | 65 | 1999 |
Synthesis and molecular modeling of novel tetrahydro-β-carboline derivatives with phosphodiesterase 5 inhibitory and anticancer properties HA Mohamed, NMR Girgis, R Wilcken, MR Bauer, HN Tinsley, BD Gary, ... Journal of medicinal chemistry 54 (2), 495-509, 2011 | 59 | 2011 |
Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties AE Ghonim, A Ligresti, A Rabbito, AM Mahmoud, V Di Marzo, NA Osman, ... European journal of medicinal chemistry 180, 154-170, 2019 | 58 | 2019 |
The voltammetric study and determination of ramipril in dosage forms and biological fluids AA Al-Majed, F Belal, A Abadi, AM Al-Obaid Il Farmaco 55 (3), 233-238, 2000 | 58 | 2000 |
Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective AH Abadi, BD Gary, HN Tinsley, GA Piazza, M Abdel-Halim European journal of medicinal chemistry 45 (4), 1278-1286, 2010 | 49 | 2010 |
Development of selective Clk1 and-4 inhibitors for cellular depletion of cancer-relevant proteins AK ElHady, M Abdel-Halim, AH Abadi, M Engel Journal of Medicinal Chemistry 60 (13), 5377-5391, 2017 | 47 | 2017 |
New NSAID targets and derivatives for colorectal cancer chemoprevention HN Tinsley, WE Grizzle, A Abadi, A Keeton, B Zhu, Y Xi, GA Piazza Prospects for Chemoprevention of Colorectal Neoplasia: Emerging Role of Anti …, 2013 | 47 | 2013 |
Discovery and optimization of 1, 3, 5-trisubstituted pyrazolines as potent and highly selective allosteric inhibitors of protein kinase C-ζ M Abdel-Halim, B Diesel, AK Kiemer, AH Abadi, RW Hartmann, M Engel Journal of medicinal chemistry 57 (15), 6513-6530, 2014 | 38 | 2014 |
Synthesis and antitubercular activity of 6-chloro (unsubstituted)-2-methoxy-9-substituted acridine derivatives EI Aly, AH Abadi Archives of pharmacal research 27, 713-719, 2004 | 37 | 2004 |