PGC-1α promotes breast cancer metastasis and confers bioenergetic flexibility against metabolic drugs S Andrzejewski, E Klimcakova, RM Johnson, S Tabariès, MG Annis, ... Cell metabolism 26 (5), 778-787. e5, 2017 | 246 | 2017 |
Tissue force programs cell fate and tumor aggression JJ Northey, L Przybyla, VM Weaver Cancer discovery 7 (11), 1224-1237, 2017 | 230 | 2017 |
Signaling through ShcA is required for transforming growth factor β-and Neu/ErbB-2-induced breast cancer cell motility and invasion JJ Northey, J Chmielecki, E Ngan, C Russo, MG Annis, WJ Muller, ... Molecular and cellular biology 28 (10), 3162-3176, 2008 | 98 | 2008 |
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217 JJ Northey, AS Barrett, I Acerbi, MK Hayward, S Talamantes, IS Dean, ... The Journal of clinical investigation 130 (11), 5721-5737, 2020 | 89 | 2020 |
Chordin-like 1 suppresses bone morphogenetic protein 4-induced breast cancer cell migration and invasion C Cyr-Depauw, JJ Northey, S Tabariès, MG Annis, Z Dong, S Cory, ... Molecular and Cellular Biology 36 (10), 1509-1525, 2016 | 65 | 2016 |
A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells E Ngan, JJ Northey, CM Brown, J Ursini-Siegel, PM Siegel Journal of cell science 126 (9), 1981-1991, 2013 | 58 | 2013 |
The Ste20-like kinase SLK is required for ErbB2-driven breast cancer cell motility K Roovers, S Wagner, CJ Storbeck, P O'reilly, V Lo, JJ Northey, ... Oncogene 28 (31), 2839-2848, 2009 | 54 | 2009 |
The Cdc42/Rac1 regulator CdGAP is a novel E-cadherin transcriptional co-repressor with Zeb2 in breast cancer Y He, JJ Northey, A Pelletier, Z Kos, L Meunier, B Haibe-Kains, ... Oncogene 36 (24), 3490-3503, 2017 | 47 | 2017 |
Matrix compliance permits NF-κB activation to drive therapy resistance in breast cancer AP Drain, N Zahir, JJ Northey, H Zhang, PJ Huang, O Maller, JN Lakins, ... Journal of Experimental Medicine 218 (5), e20191360, 2021 | 43 | 2021 |
CdGAP is required for transforming growth factor β-and Neu/ErbB-2-induced breast cancer cell motility and invasion Y He, JJ Northey, M Primeau, RD Machado, R Trembath, PM Siegel, ... Oncogene 30 (9), 1032-1045, 2011 | 42 | 2011 |
Tissue force programs cell fate and tumor aggression. Cancer Discov. 2017; 7: 1224–1237. doi: 10.1158/2159-8290 JJ Northey, L Przybyla, VM Weaver CD-16-0733.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 34 | |
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins K Pedram, DJ Shon, GS Tender, NR Mantuano, JJ Northey, KJ Metcalf, ... Nature biotechnology 42 (4), 597-607, 2024 | 32 | 2024 |
Distinct phosphotyrosine-dependent functions of the ShcA adaptor protein are required for transforming growth factor β (TGFβ)-induced breast cancer cell migration, invasion … JJ Northey, Z Dong, E Ngan, A Kaplan, WR Hardy, T Pawson, PM Siegel Journal of Biological Chemistry 288 (7), 5210-5222, 2013 | 32 | 2013 |
Targeting aberrant TGF-β signaling in pre-clinical models of cancer AA Mourskaia, JJ Northey, PM Siegel Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2007 | 30 | 2007 |
Screening of organoids derived from patients with breast cancer implicates the repressor NCOR2 in cytotoxic stress response and antitumor immunity KK Tsai, SS Huang, JJ Northey, WY Liao, CC Hsu, LH Cheng, ME Werner, ... Nature Cancer 3 (6), 734-752, 2022 | 22 | 2022 |
Fighting the force: Potential of homeobox genes for tumor microenvironment regulation JM Northcott, JJ Northey, JM Barnes, VM Weaver Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 1855 (2), 248-253, 2015 | 16 | 2015 |
ECM dimensionality tunes actin tension to modulate endoplasmic reticulum function and spheroid phenotypes of mammary epithelial cells FB Kai, G Ou, RW Tourdot, C Stashko, G Gaietta, MF Swift, N Volkmann, ... The EMBO Journal 41 (17), e109205, 2022 | 14 | 2022 |
New horizons in advocacy engaged physical sciences and oncology research S Samson, JJ Northey, V Plaks, C Baas, I Dean, MA LaBarge, A Goga, ... Trends in cancer 4 (4), 260-264, 2018 | 9 | 2018 |
A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer C Stashko, MK Hayward, JJ Northey, N Pearson, AJ Ironside, JN Lakins, ... Nature communications 14 (1), 3561, 2023 | 8 | 2023 |
Mechanosensitive steroid hormone signaling and cell fate JJ Northey, VM Weaver Endocrinology 163 (8), bqac085, 2022 | 8 | 2022 |