| Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice H Azuma, N Paulk, A Ranade, C Dorrell, M Al-Dhalimy, E Ellis, S Strom, ... Nature Biotechnology 25 (8), 903-910, 2007 | 911 | 2007 |
| Promoterless gene targeting without nucleases ameliorates haemophilia B in mice A Barzel, NK Paulk, Y Shi, Y Huang, K Chu, F Zhang, P Valdmanis, ... Nature 517 (7534), 360-364, 2015 | 284 | 2015 |
| Bioengineered AAV capsids with combined high human liver transduction in vivo and unique humoral seroreactivity NK Paulk, K Pekrun, E Zhu, S Nygaard, B Li, J Xu, K Chu, C Leborgne, ... Molecular Therapy, 2017 | 182 | 2017 |
| Adeno‐associated virus gene repair corrects a mouse model of hereditary tyrosinemia in vivo NK Paulk, K Wursthorn, Z Wang, M Finegold, M Kay, M Grompe Hepatology 51 (4), 1200-1208, 2010 | 153 | 2010 |
| Rescue of Pompe disease in mice by AAV-mediated liver delivery of secretable acid α-glucosidase F Puzzo, P Colella, MG Biferi, D Bali, NK Paulk, P Vidal, F Collaud, ... Science Translational Medicine 9 (418), eaam6375, 2017 | 123 | 2017 |
| Ploidy reductions in murine fusion-derived hepatocytes A Duncan, R Hickey, NK Paulk, A Culberson, S Olson, M Finegold, ... PLoS Genetics 5 (2), e1000385, 2009 | 123 | 2009 |
| Methods matter: standard production platforms for recombinant AAV produce chemically and functionally distinct vectors NG Rumachik, SA Malaker, N Poweleit, LH Maynard, CM Adams, RD Leib, ... Molecular therapy Methods & clinical development 18, 98-118, 2020 | 114 | 2020 |
| Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity. IP Winters, SH Chiou, NK Paulk, CD McFarland, PV Lalgudi, RK Ma, L Lisowski ... Nature Communications 8 (2053), 2017 | 103 | 2017 |
| Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition A Taylor, A Preston, NK Paulk, H Sutherland, C Keenan, P Wilson, ... Osteoarthritis and Cartilage 20 (8), 880-886, 2012 | 54 | 2012 |
| Gene Therapy: It Is Time to Talk about High-Dose AAV: The deaths of two children with X-linked myotubular myopathy in the ASPIRO trial prompts a reexamination of vector safety N Paulk Genetic Engineering & Biotechnology News 40 (9), 14-16, 2020 | 43 | 2020 |
| An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging Y Oh, Y Park, JH Cho, H Wu, NK Paulk, LX Liu, N Kim, MA Kay, JC Wu, ... Nature chemical biology 15 (5), 433-436, 2019 | 42 | 2019 |
| AAV-mediated gene targeting is significantly enhanced by transient inhibition of nonhomologous end joining or the proteasome in vivo NK Paulk, LM Loza, MJ Finegold, M Grompe Human Gene Therapy 23 (6), 658-665, 2012 | 41 | 2012 |
| Recombinant adeno-associated virus capsids with enhanced human skeletal muscle tropism MA Kay, NK Paulk US Patent 10,385,320, 2019 | 37 | 2019 |
| Novel Recombinant Adeno-Associated Virus Capsids with Enhanced Human Skeletal Muscle Tropism MA Kay, NK Paulk US Patent App. 15/367,734, 2016 | 37* | 2016 |
| Bioengineered viral platform for intramuscular passive vaccine delivery to human skeletal muscle NK Paulk, K Pekrun, GW Charville, K Maguire-Nguyen, MN Wosczyna, ... Molecular Therapy Methods & Clinical Development 10, 144-155, 2018 | 30 | 2018 |
| In vivo selection of transplanted hepatocytes by pharmacological inhibition of fumarylacetoacetate hydrolase in wild-type mice NK Paulk, K Wursthorn, A Haft, C Pelz, G Clarke, AH Newell, SB Olson, ... Molecular Therapy 20 (10), 1981-1987, 2012 | 19 | 2012 |
| Photochemistry of iron in simulated crustal aerosols with dimethyl sulfide oxidation products JM Key, N Paulk, AM Johansen Environmental Science & Technology 42 (1), 133-139, 2007 | 19 | 2007 |
| Fast-Seq: a simple method for rapid and inexpensive validation of packaged single-stranded adeno-associated viral genomes in academic settings LH Maynard, O Smith, NP Tilmans, E Tham, S Hosseinzadeh, W Tan, ... Human gene therapy methods 30 (6), 195-205, 2019 | 18 | 2019 |
| Comparison of highly pure rAAV9 vector stocks produced in suspension by PEI transfection or HSV infection reveals striking quantitative and qualitative differences PD Trivedi, C Yu, P Chaudhuri, EJ Johnson, T Caton, L Adamson, ... Molecular Therapy-Methods & Clinical Development 24, 154-170, 2022 | 17 | 2022 |
| VectorMOD: Method for bottom-up proteomic characterization of rAAV capsid post-translational modifications and vector impurities NG Rumachik, SA Malaker, NK Paulk Frontiers in Immunology 12, 657795, 2021 | 12 | 2021 |
Stephen StromKarolinska Institutet, Previously University of Pittsburgh在 ki.se 的电子邮件经过验证
