| Ascorbic acid–induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma N Shenoy, TD Bhagat, J Cheville, C Lohse, S Bhattacharyya, A Tischer, ... The Journal of clinical investigation 129 (4), 1612-1625, 2019 | 80 | 2019 |
| Complexity in the binding of minor groove agents: netropsin has two thermodynamically different DNA binding modes at a single site EA Lewis, M Munde, S Wang, M Rettig, V Le, V Machha, WD Wilson Nucleic acids research 39 (22), 9649-9658, 2011 | 47 | 2011 |
| Functional succinate dehydrogenase deficiency is a common adverse feature of clear cell renal cancer RK Aggarwal, RA Luchtel, V Machha, A Tischer, Y Zou, K Pradhan, ... Proceedings of the National Academy of Sciences 118 (39), e2106947118, 2021 | 43 | 2021 |
| Mutational constraints on local unfolding inhibit the rheological adaptation of von Willebrand factor A Tischer, JC Campbell, VR Machha, L Moon-Tasson, LM Benson, ... Journal of Biological Chemistry 291 (8), 3848-3859, 2016 | 31 | 2016 |
| Enhanced local disorder in a clinically elusive von willebrand factor provokes high-affinity platelet clumping A Tischer, VR Machha, JP Frontroth, MA Brehm, T Obser, ... Journal of molecular biology 429 (14), 2161-2177, 2017 | 23 | 2017 |
| Glycosylation sterically inhibits platelet adhesion to von Willebrand factor without altering intrinsic conformational dynamics A Tischer, VR Machha, L Moon‐Tasson, LM Benson, M Auton Journal of Thrombosis and Haemostasis 18 (1), 79-90, 2020 | 19 | 2020 |
| The chaperonin GroEL: a versatile tool for applied biotechnology platforms PT O'Neil, AJ Machen, BC Deatherage, C Trecazzi, A Tischer, VR Machha, ... Frontiers in molecular biosciences 5, 46, 2018 | 14 | 2018 |
| The von willebrand factor a1–collagen III interaction is independent of conformation and type 2 von willebrand disease phenotype VR Machha, A Tischer, L Moon-Tasson, M Auton Journal of molecular biology 429 (1), 32-47, 2017 | 14 | 2017 |
| Isolation and determination of the primary structure of a lectin protein from the serum of the American alligator (Alligator mississippiensis) LNF Darville, ME Merchant, V Maccha, VR Siddavarapu, A Hasan, ... Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 2012 | 11 | 2012 |
| Evidence for the misfolding of the a1 domain within multimeric von Willebrand factor in type 2 von Willebrand disease A Tischer, MA Brehm, VR Machha, L Moon-Tasson, LM Benson, ... Journal of molecular biology 432 (2), 305-323, 2020 | 10 | 2020 |
| Platelet‐type von Willebrand disease: Local disorder of the platelet GPIbα β‐switch drives high‐affinity binding to von Willebrand factor A Tischer, VR Machha, L Moon‐Tasson, M Auton Journal of Thrombosis and Haemostasis 17 (12), 2022-2034, 2019 | 8 | 2019 |
| Data on the purification and crystallization of the loss-of-function von Willebrand disease variant (p. Gly1324Ser) of the von Willebrand factor A1 domain JC Campbell, A Tischer, V Machha, L Moon-Tasson, B Sankaran, C Kim, ... Data in brief 7, 1700-1706, 2016 | 8 | 2016 |
| Calorimetric studies of the interactions of linker histone H10 and its carboxyl (H10–C) and globular (H10–G) domains with calf-thymus DNA VR Machha, JR Waddle, AL Turner, S Wellman, VH Le, EA Lewis Biophysical Chemistry 184, 22-28, 2013 | 7 | 2013 |
| Exploring the energetics of histone H1. 1 and H1. 4 duplex DNA interactions VR Machha, SB Jones, JR Waddle, VH Le, S Wellman, EA Lewis Biophysical Chemistry 185, 32-38, 2014 | 5 | 2014 |
| “Cooperative collapse” of the denatured state revealed through Clausius‐Clapeyron analysis of protein denaturation phase diagrams A Tischer, VR Machha, J Rösgen, M Auton Biopolymers 109 (8), e23106, 2018 | 4 | 2018 |
| Functional succinate dehydrogenase deficiency is a pathognomonic adverse feature of clear cell renal cancer RK Aggarwal, Y Zou, RA Luchtel, K Pradhan, N Ashai, N Ramachandra, ... bioRxiv 118, e2106947118, 2020 | 3 | 2020 |
| The Thermodynamic Effects of Ligand Structure on the Molecular Recognition of Mono‐and Bi‐Ruthenium Polypyridyl Complexes with G‐quadruplex DNA CG Mikek, VR Machha, JC White, LR Martin, SJ West, A Butrin, ... European Journal of Inorganic Chemistry, 2017 | 3 | 2017 |
| Temperature and osmotic stress dependence of the thermodynamics for binding linker histone H10, Its carboxyl domain (H10-C) or globular domain (H10-G) to B-DNA VR Machha, CG Mikek, S Wellman, EA Lewis Biochemistry and Biophysics Reports 12, 158-165, 2017 | 2 | 2017 |
| The Thermodynamic Effects of Ligand Structure on the Molecular Recognition of Mononuclear Ruthenium Polypyridyl Complexes with B‐DNA C Mikek, JI DuPont, VR Machha, JC White, LR Martin, N Alatrash, ... European Journal of Inorganic Chemistry, 2017 | 1 | 2017 |
| Effects of leukocyte extract from the American alligator (Alligator mississippiensis) on antibiotic-resistant bacteria V Machha, P Spencer, M Merchant The Open Zoology Journal 4 (1), 2011 | 1 | 2011 |
Alexander TischerResearch Associate in Hematology, Mayo Clinic在 mayo.edu 的电子邮件经过验证
