Myc and cell cycle control G Bretones, MD Delgado, J León Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1849 (5), 506-516, 2015 | 814 | 2015 |
Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter S Wu, C Cetinkaya, MJ Munoz-Alonso, N Von Der Lehr, F Bahram, ... Oncogene 22 (3), 351-360, 2003 | 410 | 2003 |
Differential Expression of the ras Gene Family in Mice J Leon, I Guerrero, A Pellicer Molecular and Cellular Biology 7 (4), 1535-1540, 1987 | 338 | 1987 |
Myc roles in hematopoiesis and leukemia MD Delgado, J León Genes & cancer 1 (6), 605-616, 2010 | 309 | 2010 |
Contributions of Myc to tumorigenesis W Lutz, J Leon, M Eilers Biochimica Et Biophysica Acta (BBA)-Reviews on Cancer 1602 (1), 61-71, 2002 | 249 | 2002 |
Ras proteins in the control of the cell cycle and cell differentiation P Crespo, J Leon Cellular and Molecular Life Sciences CMLS 57, 1613-1636, 2000 | 246 | 2000 |
MYC oncogene contributions to release of cell cycle brakes L García-Gutiérrez, MD Delgado, J León Genes 10 (3), 244, 2019 | 211 | 2019 |
Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF EM Klenova, IV Chernukhin, A El-Kady, RE Lee, EM Pugacheva, ... Molecular and cellular biology 21 (6), 2221-2234, 2001 | 146 | 2001 |
Cell growth inhibition by the multifunctional multivalent zinc-finger factor CTCF JEJ Rasko, EM Klenova, J Leon, GN Filippova, DI Loukinov, S Vatolin, ... Cancer research 61 (16), 6002-6007, 2001 | 135 | 2001 |
Oncogene activation in human benign tumors of the skin (keratoacanthomas): is HRAS involved in differentiation as well as proliferation? M Corominas, H Kamino, J Leon, A Pellicer Proceedings of the National Academy of Sciences 86 (16), 6372-6376, 1989 | 129 | 1989 |
p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells MJ Muñoz-Alonso, JC Acosta, C Richard, MD Delgado, J Sedivy, J León Journal of Biological Chemistry 280 (18), 18120-18129, 2005 | 126 | 2005 |
Targeting of CTCF to the nucleolus inhibits nucleolar transcription through a poly (ADP-ribosyl) ation-dependent mechanism V Torrano, J Navascués, F Docquier, R Zhang, LJ Burke, I Chernukhin, ... Journal of cell science 119 (9), 1746-1759, 2006 | 118 | 2006 |
Rho-regulated signals induce apoptosis in vitro and in vivo by a p53-independent, but Bcl2 dependent pathway P Esteve, N Embade, R Perona, B Jiménez, L Peso, J León, M Arends, ... Oncogene 17 (14), 1855-1869, 1998 | 118 | 1998 |
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27KIP1 through SKP2 in human leukemia cells G Bretones, JC Acosta, JM Caraballo, N Ferrándiz, MT Gómez-Casares, ... Journal of Biological Chemistry 286 (11), 9815-9825, 2011 | 117 | 2011 |
Prolactin induces c-Myc expression and cell survival through activation of Src/Akt pathway in lymphoid cells MA Domínguez-Cáceres, JM García-Martínez, A Calcabrini, L Gonzalez, ... Oncogene 23 (44), 7378-7390, 2004 | 105 | 2004 |
CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells V Torrano, I Chernukhin, F Docquier, V D'Arcy, J León, E Klenova, ... Journal of Biological Chemistry 280 (30), 28152-28161, 2005 | 99 | 2005 |
Differential regulation of Max and role of c-Myc during erythroid and myelomonocytic differentiation of K562 cells MD Delgado, A Lerga, M Cañelles, MT Gómez-Casares, J León Oncogene 10 (8), 1659-1666, 1995 | 94 | 1995 |
H-ras activation in benign and self-regressing skin tumors (keratoacanthomas) in both humans and an animal model system J Leon, H Kamino, JJ Steinberg, A Pellicer Molecular and cellular biology, 1988 | 90 | 1988 |
Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis? J Leon, N Ferrandiz, JC Acosta, MD Delgado Cell cycle 8 (8), 1148-1157, 2009 | 89 | 2009 |
Susceptibility of HIV-1-TAT transfected cells to undergo apoptosis. Biochemical mechanisms A Macho, MA Calzado, E Ceballos Oncogene 18 (52), 7543-7551, 1999 | 89 | 1999 |