Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells MB Fuertes, AK Kacha, J Kline, SR Woo, DM Kranz, KM Murphy, ... Journal of Experimental Medicine 208 (10), 2005-2016, 2011 | 1257 | 2011 |
Positive and negative selection of an antigen receptor on T cells in transgenic mice WC Sha, CA Nelson, RD Newberry, DM Kranz, JH Russell, DY Loh Nature 336 (6194), 73-76, 1988 | 946 | 1988 |
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences H Saito, DM Kranz, Y Takagaki, AC Hayday, HN Eisen, S Tonegawa Nature 309 (5971), 757-762, 1984 | 874 | 1984 |
A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes H Saito, DM Kranz, Y Takagaki, AC Hayday, HN Eisen, S Tonegawa Nature 312 (5989), 36-40, 1984 | 659 | 1984 |
Engineered CAR T cells targeting the cancer-associated Tn-glycoform of the membrane mucin MUC1 control adenocarcinoma AD Posey, RD Schwab, AC Boesteanu, C Steentoft, U Mandel, B Engels, ... Immunity 44 (6), 1444-1454, 2016 | 605 | 2016 |
Engineering human ACE2 to optimize binding to the spike protein of SARS coronavirus 2 KK Chan, D Dorosky, P Sharma, SA Abbasi, JM Dye, DM Kranz, ... Science 369 (6508), 1261-1265, 2020 | 561 | 2020 |
Structure, organization, and somatic rearrangement of T cell gamma genes AC Hayday, H Saito, SD Gillies, DM Kranz, G Tanigawa, HN Eisen, ... Cell 40 (2), 259-269, 1985 | 532 | 1985 |
T‐cell receptor binding affinities and kinetics: impact on T‐cell activity and specificity JD Stone, AS Chervin, DM Kranz Immunology 126 (2), 165-176, 2009 | 480 | 2009 |
Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation PD Holler, DM Kranz Immunity 18 (2), 255-264, 2003 | 458 | 2003 |
Yeast cell surface display of proteins and uses thereof KD Wittrup, DM Kranz, M Kieke, ET Boder US Patent 6,699,658, 2004 | 416 | 2004 |
In vitro evolution of a T cell receptor with high affinity for peptide/MHC PD Holler, PO Holman, EV Shusta, S O'Herrin, KD Wittrup, DM Kranz Proceedings of the National Academy of Sciences 97 (10), 5387-5392, 2000 | 412 | 2000 |
Induced sensitization of tumor stroma leads to eradication of established cancer by T cells B Zhang, NA Bowerman, JK Salama, H Schmidt, MT Spiotto, ... The Journal of experimental medicine 204 (1), 49-55, 2007 | 405 | 2007 |
Efficient tumor cell lysis mediated by a bispecific single chain antibody expressed in Escherichia coli. M Gruber, BA Schodin, ER Wilson, DM Kranz Journal of immunology (Baltimore, Md.: 1950) 152 (11), 5368-5374, 1994 | 399 | 1994 |
Directed evolution of a stable scaffold for T-cell receptor engineering EV Shusta, PD Holler, MC Kieke, DM Kranz, KD Wittrup Nature biotechnology 18 (7), 754-759, 2000 | 343 | 2000 |
Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency EV Shusta, MC Kieke, E Parke, DM Kranz, KD Wittrup Journal of molecular biology 292 (5), 949-956, 1999 | 321 | 1999 |
How a single T cell receptor recognizes both self and foreign MHC LA Colf, AJ Bankovich, NA Hanick, NA Bowerman, LL Jones, DM Kranz, ... Cell 129 (1), 135-146, 2007 | 310 | 2007 |
T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex JJ Adams, S Narayanan, B Liu, ME Birnbaum, AC Kruse, NA Bowerman, ... Immunity 35 (5), 681-693, 2011 | 291 | 2011 |
Selection of functional T cell receptor mutants from a yeast surface-display library MC Kieke, EV Shusta, ET Boder, L Teyton, KD Wittrup, DM Kranz Proceedings of the National Academy of Sciences 96 (10), 5651-5656, 1999 | 287 | 1999 |
Adoptive T cell therapies: a comparison of T cell receptors and chimeric antigen receptors DT Harris, DM Kranz Trends in pharmacological sciences 37 (3), 220-230, 2016 | 281 | 2016 |
TCRs with high affinity for foreign pMHC show self-reactivity PD Holler, LK Chlewicki, DM Kranz Nature immunology 4 (1), 55-62, 2003 | 278 | 2003 |