Structural basis for the modulation of voltage-gated sodium channels by animal toxins H Shen, Z Li, Y Jiang, X Pan, J Wu, B Cristofori-Armstrong, JJ Smith, ... Science 362 (6412), eaau2596, 2018 | 226 | 2018 |
Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy C Simons, LD Rash, J Crawford, L Ma, B Cristofori-Armstrong, D Miller, ... Nature genetics 47 (1), 73-77, 2015 | 151 | 2015 |
Animal toxins—Nature’s evolutionary-refined toolkit for basic research and drug discovery V Herzig, B Cristofori-Armstrong, MR Israel, SA Nixon, I Vetter, GF King Biochemical pharmacology 181, 114096, 2020 | 126 | 2020 |
ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins SS Pineda, PA Chaumeil, A Kunert, Q Kaas, MWC Thang, L Le, M Nuhn, ... Bioinformatics 34 (6), 1074-1076, 2018 | 111 | 2018 |
Acid-sensing ion channel (ASIC) structure and function: Insights from spider, snake and sea anemone venoms B Cristofori-Armstrong, LD Rash Neuropharmacology 127, 173-184, 2017 | 97 | 2017 |
Inhibition of acid‐sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain JYP Lee, NJ Saez, B Cristofori‐Armstrong, R Anangi, GF King, MT Smith, ... British Journal of Pharmacology 175 (12), 2204-2218, 2018 | 55 | 2018 |
Understanding the molecular basis of toxin promiscuity: The analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping … JE Jensen, B Cristofori-Armstrong, R Anangi, KJ Rosengren, CHY Lau, ... Journal of medicinal chemistry 57 (21), 9195-9203, 2014 | 54 | 2014 |
Defining the role of post-synaptic α-neurotoxins in paralysis due to snake envenoming in humans A Silva, B Cristofori-Armstrong, LD Rash, WC Hodgson, GK Isbister Cellular and molecular life sciences 75, 4465-4478, 2018 | 46 | 2018 |
PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold B Madio, S Peigneur, YKY Chin, BR Hamilton, ST Henriques, JJ Smith, ... Cellular and molecular life sciences 75, 4511-4524, 2018 | 43 | 2018 |
Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid‐sensing ion channel 1a NJ Saez, E Deplazes, B Cristofori‐Armstrong, IR Chassagnon, X Lin, ... British journal of pharmacology 172 (20), 4985-4995, 2015 | 40 | 2015 |
Discovery and molecular interaction studies of a highly stable, tarantula peptide modulator of acid-sensing ion channel 1 SY Er, B Cristofori-Armstrong, P Escoubas, LD Rash Neuropharmacology 127, 185-195, 2017 | 35 | 2017 |
The modulation of acid-sensing ion channel 1 by PcTx1 is pH-, subtype-and species-dependent: Importance of interactions at the channel subunit interface and potential for … B Cristofori-Armstrong, NJ Saez, IR Chassagnon, GF King, LD Rash Biochemical Pharmacology 163, 381-390, 2019 | 33 | 2019 |
Three peptide modulators of the human voltage-gated sodium channel 1.7, an important analgesic target, from the venom of an Australian tarantula CY Chow, B Cristofori-Armstrong, EAB Undheim, GF King, LD Rash Toxins 7 (7), 2494-2513, 2015 | 33 | 2015 |
The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins AN Miller, PR Houlihan, E Matamala, D Cabezas-Bratesco, GY Lee, ... Elife 12, e84477, 2023 | 29 | 2023 |
A Strategy for Production of Correctly Folded Disulfide-Rich Peptides in the Periplasm of E. coli NJ Saez, B Cristofori-Armstrong, R Anangi, GF King Heterologous Gene Expression in E. coli: Methods and Protocols, 155-180, 2017 | 29 | 2017 |
The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity JS Wingerd, CA Mozar, CA Ussing, SS Murali, YKY Chin, ... Scientific reports 7 (1), 974, 2017 | 21 | 2017 |
Xenopus borealis as an alternative source of oocytes for biophysical and pharmacological studies of neuronal ion channels B Cristofori-Armstrong, MS Soh, S Talwar, DL Brown, JDO Griffin, Z Dekan, ... Scientific reports 5 (1), 14763, 2015 | 21 | 2015 |
Visualizing synaptic dopamine efflux with a 2D composite nanofilm C Bulumulla, AT Krasley, B Cristofori-Armstrong, WC Valinsky, D Walpita, ... elife 11, e78773, 2022 | 20 | 2022 |
Novel conorfamides from Conus austini venom modulate both nicotinic acetylcholine receptors and acid-sensing ion channels A Jin, B Cristofori-Armstrong, LD Rash, SA Roman-Gonzalez, ... Biochemical Pharmacology 164, 342-348, 2019 | 16 | 2019 |
Mambalgin-3 potentiates human acid-sensing ion channel 1b under mild to moderate acidosis: Implications as an analgesic lead B Cristofori-Armstrong, E Budusan, LD Rash Proceedings of the National Academy of Sciences 118 (8), e2021581118, 2021 | 15 | 2021 |