| Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans K Adelman, JT Lis Nature Reviews Genetics 13 (10), 720-731, 2012 | 1321 | 2012 |
| RNA polymerase is poised for activation across the genome GW Muse, DA Gilchrist, S Nechaev, R Shah, JS Parker, SF Grissom, ... Nature genetics 39 (12), 1507-1511, 2007 | 888 | 2007 |
| RNA polymerase stalling at developmental control genes in the Drosophila melanogaster embryo J Zeitlinger, A Stark, M Kellis, JW Hong, S Nechaev, K Adelman, M Levine, ... Nature genetics 39 (12), 1512-1516, 2007 | 882 | 2007 |
| Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila S Nechaev, DC Fargo, G dos Santos, L Liu, Y Gao, K Adelman Science 327 (5963), 335-338, 2010 | 480 | 2010 |
| Pausing of RNA polymerase II disrupts DNA-specified nucleosome organization to enable precise gene regulation DA Gilchrist, G Dos Santos, DC Fargo, B Xie, Y Gao, L Li, K Adelman Cell 143 (4), 540-551, 2010 | 466 | 2010 |
| CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1 B Bartkowiak, P Liu, HP Phatnani, NJ Fuda, JJ Cooper, DH Price, ... Genes & development 24 (20), 2303-2316, 2010 | 452 | 2010 |
| Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation L Core, K Adelman Genes & development 33 (15-16), 960-982, 2019 | 446 | 2019 |
| Mll3 and Mll4 facilitate enhancer RNA synthesis and transcription from promoters independently of H3K4 monomethylation KM Dorighi, T Swigut, T Henriques, NV Bhanu, BS Scruggs, N Nady, ... Molecular cell 66 (4), 568-576. e4, 2017 | 376 | 2017 |
| Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation S Nechaev, K Adelman Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1809 (1), 34-45, 2011 | 342 | 2011 |
| NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly DA Gilchrist, S Nechaev, C Lee, SKB Ghosh, JB Collins, L Li, DS Gilmour, ... Genes & development 22 (14), 1921-1933, 2008 | 340 | 2008 |
| Widespread transcriptional pausing and elongation control at enhancers T Henriques, BS Scruggs, MO Inouye, GW Muse, LH Williams, ... Genes & development 32 (1), 26-41, 2018 | 314 | 2018 |
| Defining the status of RNA polymerase at promoters LJ Core, JJ Waterfall, DA Gilchrist, DC Fargo, H Kwak, K Adelman, JT Lis Cell reports 2 (4), 1025-1035, 2012 | 275 | 2012 |
| Mapping information-rich genotype-phenotype landscapes with genome-scale Perturb-seq JM Replogle, RA Saunders, AN Pogson, JA Hussmann, A Lenail, A Guna, ... Cell 185 (14), 2559-2575. e28, 2022 | 267 | 2022 |
| Stable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals T Henriques, DA Gilchrist, S Nechaev, M Bern, GW Muse, A Burkholder, ... Molecular cell 52 (4), 517-528, 2013 | 258 | 2013 |
| Bidirectional transcription arises from two distinct hubs of transcription factor binding and active chromatin BS Scruggs, DA Gilchrist, S Nechaev, GW Muse, A Burkholder, DC Fargo, ... Molecular cell 58 (6), 1101-1112, 2015 | 238 | 2015 |
| Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior K Adelman, A La Porta, TJ Santangelo, JT Lis, JW Roberts, MD Wang Proceedings of the National Academy of Sciences 99 (21), 13538-13543, 2002 | 235 | 2002 |
| PCIF1 catalyzes m6Am mRNA methylation to regulate gene expression E Sendinc, D Valle-Garcia, A Dhall, H Chen, T Henriques, ... Molecular cell 75 (3), 620-630. e9, 2019 | 229 | 2019 |
| Molecular mechanism of transcription inhibition by peptide antibiotic Microcin J25 K Adelman, J Yuzenkova, A La Porta, N Zenkin, J Lee, JT Lis, S Borukhov, ... Molecular cell 14 (6), 753-762, 2004 | 199 | 2004 |
| Spt6 enhances the elongation rate of RNA polymerase II in vivo MB Ardehali, J Yao, K Adelman, NJ Fuda, SJ Petesch, WW Webb, JT Lis The EMBO journal 28 (8), 1067-1077, 2009 | 193 | 2009 |
| Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS K Adelman, MT Marr, J Werner, A Saunders, Z Ni, ED Andrulis, JT Lis Molecular cell 17 (1), 103-112, 2005 | 192 | 2005 |
Sergei NechaevUND School of Medicine在 med.und.edu 的电子邮件经过验证
