| Rational design of shepherdin, a novel anticancer agent J Plescia, W Salz, F Xia, M Pennati, N Zaffaroni, MG Daidone, M Meli, ... Cancer cell 7 (5), 457-468, 2005 | 423 | 2005 |
| Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90 BH Kang, J Plescia, HY Song, M Meli, G Colombo, K Beebe, B Scroggins, ... The Journal of clinical investigation 119 (3), 454-464, 2009 | 256 | 2009 |
| Antileukemic activity of shepherdin and molecular diversity of hsp90 inhibitors B Gyurkocza, J Plescia, CM Raskett, DS Garlick, PA Lowry, BZ Carter, ... Journal of the National Cancer Institute 98 (15), 1068-1077, 2006 | 119 | 2006 |
| Pharmacological enhancement of α-glucosidase by the allosteric chaperone N-acetylcysteine C Porto, MC Ferrara, M Meli, E Acampora, V Avolio, M Rosa, ... Molecular Therapy 20 (12), 2201-2211, 2012 | 116 | 2012 |
| Small-molecule targeting of heat shock protein 90 chaperone function: rational identification of a new anticancer lead M Meli, M Pennati, M Curto, MG Daidone, J Plescia, S Toba, DC Altieri, ... Journal of medicinal chemistry 49 (26), 7721-7730, 2006 | 111 | 2006 |
| A multiscale approach to characterize the early aggregation steps of the amyloid-forming peptide GNNQQNY from the yeast prion sup-35 J Nasica-Labouze, M Meli, P Derreumaux, G Colombo, N Mousseau PLoS Computational Biology 7 (5), e1002051, 2011 | 89 | 2011 |
| Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution G Colombo, G Morra, M Meli, G Verkhivker Proceedings of the National Academy of Sciences 105 (23), 7976-7981, 2008 | 85 | 2008 |
| Synthesis, Structure and Conformation of Partially‐Modified Retro‐ and Retro‐Inverso ψ[NHCH(CF3)]Gly Peptides A Volonterio, S Bellosta, F Bravin, MC Bellucci, L Bruché, G Colombo, ... Chemistry–A European Journal 9 (18), 4510-4522, 2003 | 82 | 2003 |
| Dynamic diagnosis of familial prion diseases supports the β2-α2 loop as a universal interference target M Meli, M Gasset, G Colombo PloS one 6 (4), e19093, 2011 | 80 | 2011 |
| Methionine sulfoxides on prion protein helix-3 switch on the α-fold destabilization required for conversion G Colombo, M Meli, G Morra, R Gabizon, M Gasset PloS one 4 (1), e4296, 2009 | 69 | 2009 |
| Effects of water miscible organic solvents on the activity and conformation of the Baeyer–Villiger monooxygenases from Thermobifida fusca and Acinetobacter calcoaceticus: a … F Secundo, S Fiala, MW Fraaije, G de Gonzalo, M Meli, F Zambianchi, ... Biotechnology and bioengineering 108 (3), 491-499, 2011 | 68 | 2011 |
| Investigating the mechanism of peptide aggregation: insights from mixed Monte Carlo-molecular dynamics simulations M Meli, G Morra, G Colombo Biophysical journal 94 (11), 4414-4426, 2008 | 57 | 2008 |
| A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro M Maggi, SD Mittelman, JH Parmentier, G Colombo, M Meli, JM Whitmire, ... Scientific reports 7 (1), 14479, 2017 | 56 | 2017 |
| Structure elucidation and 3D solution conformation of the antibiotic enduracidin determined by NMR spectroscopy and molecular dynamics F Castiglione, A Marazzi, M Meli, G Colombo Magnetic Resonance in Chemistry 43 (8), 603-610, 2005 | 42 | 2005 |
| The answer lies in the energy: how simple atomistic molecular dynamics simulations may hold the key to epitope prediction on the fully glycosylated SARS-CoV-2 spike protein SA Serapian, F Marchetti, A Triveri, G Morra, M Meli, E Moroni, GA Sautto, ... The Journal of Physical Chemistry Letters 11 (19), 8084-8093, 2020 | 40 | 2020 |
| A Hamiltonian replica exchange molecular dynamics (MD) method for the study of folding, based on the analysis of the stabilization determinants of proteins M Meli, G Colombo International journal of molecular sciences 14 (6), 12157-12169, 2013 | 39 | 2013 |
| Canada J, Asensio JL and Jimenez-Barbero J 2004 Toward the understanding of the structure and dynamics of protein-carbohydrate interactions, molecular dynamics studies of the … G Colombo, M Meli Carbohydr. Res 339, 985-994, 0 | 34 | |
| Crystal structure of the DFNKF segment of human calcitonin unveils aromatic interactions between phenylalanines A Bertolani, A Pizzi, L Pirrie, L Gazzera, G Morra, M Meli, G Colombo, ... Chemistry–A European Journal 23 (9), 2051-2058, 2017 | 32 | 2017 |
| Molecular dynamics simulations of proteins and peptides: from folding to drug design G Morra, M Meli, G Colombo Current Protein and Peptide Science 9 (2), 181-196, 2008 | 31 | 2008 |
| The five-to-six-coordination transition of ferric human serum heme-albumin is allosterically-modulated by ibuprofen and warfarin: A combined XAS and MD study C Meneghini, L Leboffe, M Bionducci, G Fanali, M Meli, G Colombo, ... PLoS One 9 (8), e104231, 2014 | 30 | 2014 |
Giorgio ColomboUniversity of Pavia在 unipv.it 的电子邮件经过验证
