Principles of activation and permeation in an anion-selective Cys-loop receptor RE Hibbs, E Gouaux Nature 474 (7349), 54-60, 2011 | 1095 | 2011 |
Structure of a human synaptic GABAA receptor S Zhu, CM Noviello, J Teng, RM Walsh Jr, JJ Kim, RE Hibbs Nature 559 (7712), 67-72, 2018 | 532 | 2018 |
X-ray structure of the human α4β2 nicotinic receptor CL Morales-Perez, CM Noviello, RE Hibbs Nature 538 (7625), 411-415, 2016 | 437 | 2016 |
X-ray structures of GluCl in apo states reveal a gating mechanism of Cys-loop receptors T Althoff, RE Hibbs, S Banerjee, E Gouaux Nature 512 (7514), 333-337, 2014 | 279 | 2014 |
A fluorescence-detection size-exclusion chromatography-based thermostability assay for membrane protein precrystallization screening M Hattori, RE Hibbs, E Gouaux Structure 20 (8), 1293-1299, 2012 | 265 | 2012 |
Shared structural mechanisms of general anaesthetics and benzodiazepines JJ Kim, A Gharpure, J Teng, Y Zhuang, RJ Howard, S Zhu, CM Noviello, ... Nature 585 (7824), 303-308, 2020 | 255 | 2020 |
Structural principles of distinct assemblies of the human α4β2 nicotinic receptor RM Walsh Jr, SH Roh, A Gharpure, CL Morales-Perez, J Teng, RE Hibbs Nature 557 (7704), 261-265, 2018 | 201 | 2018 |
Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore TT Talley, M Harel, RE Hibbs, Z Radić, M Tomizawa, JE Casida, P Taylor Proceedings of the National Academy of Sciences 105 (21), 7606-7611, 2008 | 189 | 2008 |
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor RE Hibbs, G Sulzenbacher, J Shi, TT Talley, S Conrod, WR Kem, P Taylor, ... The EMBO journal 28 (19), 3040-3051, 2009 | 187 | 2009 |
Structure and gating mechanism of the α7 nicotinic acetylcholine receptor CM Noviello, A Gharpure, N Mukhtasimova, R Cabuco, L Baxter, D Borek, ... Cell 184 (8), 2121-2134. e13, 2021 | 177 | 2021 |
Structure of the native muscle-type nicotinic receptor and inhibition by snake venom toxins MM Rahman, J Teng, BT Worrell, CM Noviello, M Lee, A Karlin, ... Neuron 106 (6), 952-962. e5, 2020 | 160 | 2020 |
Agonist selectivity and ion permeation in the α3β4 ganglionic nicotinic receptor A Gharpure, J Teng, Y Zhuang, CM Noviello, RM Walsh, R Cabuco, ... Neuron 104 (3), 501-511. e6, 2019 | 145 | 2019 |
Chemical and structural analysis of a photoactive vertebrate cryptochrome from pigeon BD Zoltowski, Y Chelliah, A Wickramaratne, L Jarocha, N Karki, W Xu, ... Proceedings of the National Academy of Sciences 116 (39), 19449-19457, 2019 | 125 | 2019 |
Manipulation of subunit stoichiometry in heteromeric membrane proteins CL Morales-Perez, CM Noviello, RE Hibbs Structure 24 (5), 797-805, 2016 | 108 | 2016 |
Direct structural insights into GABAA receptor pharmacology JJ Kim, RE Hibbs Trends in biochemical sciences 46 (6), 502-517, 2021 | 81 | 2021 |
Progress in nicotinic receptor structural biology A Gharpure, CM Noviello, RE Hibbs Neuropharmacology 171, 108086, 2020 | 77 | 2020 |
Acrylodan-conjugated cysteine side chains reveal conformational state and ligand site locations of the acetylcholine-binding protein RE Hibbs, TT Talley, P Taylor Journal of Biological Chemistry 279 (27), 28483-28491, 2004 | 69 | 2004 |
Structure-guided drug design: conferring selectivity among neuronal nicotinic receptor and acetylcholine-binding protein subtypes P Taylor, TT Talley, SB Hansen, RE Hibbs, J Shi Biochemical pharmacology 74 (8), 1164-1171, 2007 | 61 | 2007 |
Structural mechanism of muscle nicotinic receptor desensitization and block by curare MM Rahman, T Basta, J Teng, M Lee, BT Worrell, MHB Stowell, RE Hibbs Nature structural & molecular biology 29 (4), 386-394, 2022 | 49 | 2022 |
Influence of agonists and antagonists on the segmental motion of residues near the agonist binding pocket of the acetylcholine-binding protein RE Hibbs, Z Radic, P Taylor, DA Johnson Journal of Biological Chemistry 281 (51), 39708-39718, 2006 | 46 | 2006 |