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Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa V Sebastiano, HH Zhen, B Haddad, E Bashkirova, SP Melo, P Wang, ... Science translational medicine 6 (264), 264ra163-264ra163, 2014 | 220 | 2014 |
Patient-specific iPSC-derived endothelial cells uncover pathways that protect against pulmonary hypertension in BMPR2 mutation carriers M Gu, NY Shao, S Sa, D Li, V Termglinchan, M Ameen, I Karakikes, ... Cell stem cell 20 (4), 490-504. e5, 2017 | 202 | 2017 |
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy J Lee, V Termglinchan, S Diecke, I Itzhaki, CK Lam, P Garg, E Lau, ... Nature 572 (7769), 335-340, 2019 | 166 | 2019 |
Human AML-iPSCs reacquire leukemic properties after differentiation and model clonal variation of disease MP Chao, AJ Gentles, S Chatterjee, F Lan, A Reinisch, MR Corces, ... Cell Stem Cell 20 (3), 329-344. e7, 2017 | 134 | 2017 |
Induced pluripotent stem cell model of pulmonary arterial hypertension reveals novel gene expression and patient specificity S Sa, M Gu, J Chappell, NY Shao, M Ameen, KAT Elliott, D Li, F Grubert, ... American journal of respiratory and critical care medicine 195 (7), 930-941, 2017 | 88 | 2017 |
Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy N Sayed, C Liu, M Ameen, F Himmati, JZ Zhang, S Khanamiri, JR Moonen, ... Science Translational Medicine 12 (554), 2020 | 67 | 2020 |
A comprehensive TALEN-based knockout library for generating human-induced pluripotent stem cell–based models for cardiovascular diseases I Karakikes, V Termglinchan, DA Cepeda, J Lee, S Diecke, A Hendel, ... Circulation research 120 (10), 1561-1571, 2017 | 64 | 2017 |
Personalized medicine in cardio-oncology: the role of induced pluripotent stem cell N Sayed, M Ameen, JC Wu Cardiovascular research 115 (5), 949-959, 2019 | 52 | 2019 |
Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates KD Wilson, M Ameen, H Guo, OJ Abilez, L Tian, MR Mumbach, S Diecke, ... Developmental Cell, 2020 | 44 | 2020 |
Transcriptomic and epigenomic differences in human induced pluripotent stem cells generated from six reprogramming methods JM Churko, J Lee, M Ameen, M Gu, M Venkatasubramanian, S Diecke, ... Nature biomedical engineering 1 (10), 826-837, 2017 | 42 | 2017 |
Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy I Perea-Gil, T Seeger, AAN Bruyneel, V Termglinchan, E Monte, EW Lim, ... European Heart Journal, 2022 | 32 | 2022 |
Comparison of magnetic resonance imaging and serum biomarkers for detection of human pluripotent stem cell-derived teratomas J Riegler, A Ebert, X Qin, Q Shen, M Wang, M Ameen, K Kodo, SG Ong, ... Stem Cell Reports 6 (2), 176-187, 2016 | 31 | 2016 |
Integrative single-cell analysis of cardiogenesis identifies developmental trajectories and non-coding mutations in congenital heart disease M Ameen, L Sundaram, M Shen, A Banerjee, S Kundu, S Nair, ... Cell 185 (26), 4937-4953. e23, 2022 | 30 | 2022 |
Transcriptome Analysis of Non-Human Primate Induced Pluripotent Stem Cell-Derived Cardiomyocytes in 2D Monolayer Culture versus 3D Engineered Heart Tissue H Yang, N Shao, A Holmström, X Zhao, T Chour, H Chen, I Itzhaki, H Wu, ... Cardiovascular Research, 2020 | 21 | 2020 |
Pharmacological Silencing of MicroRNA-152 Prevents Pressure Overload–Induced Heart Failure TJ LaRocca, T Seeger, M Prado, I Perea-Gil, E Neofytou, BH Mecham, ... Circulation: Heart Failure 13 (3), e006298, 2020 | 20 | 2020 |
Magnetic resonance imaging of cardiac strain pattern following transplantation of human tissue engineered heart muscles X Qin, J Riegler, M Tiburcy, X Zhao, T Chour, B Ndoye, M Nguyen, ... Circulation: Cardiovascular Imaging 9 (11), e004731, 2016 | 20 | 2016 |
Statins improve endothelial function via suppression of epigenetic-driven EndMT C Liu, M Shen, WLW Tan, IY Chen, Y Liu, X Yu, H Yang, A Zhang, Y Liu, ... Nature Cardiovascular Research, 1-19, 2023 | 19 | 2023 |
Identification of constrained sequence elements across 239 primate genomes LFK Kuderna, JC Ulirsch, S Rashid, M Ameen, L Sundaram, G Hickey, ... Nature, 1-8, 2023 | 11 | 2023 |
Stepwise Generation of Human Induced Pluripotent Stem Cell–Derived Cardiac Pericytes to Model Coronary Microvascular Dysfunction M Shen, C Liu, SR Zhao, A Manhas, L Sundaram, M Ameen, JC Wu Circulation 147 (6), 515-518, 2023 | 10 | 2023 |