| Structure of the p53 binding domain of HAUSP/USP7 bound to Epstein-Barr nuclear antigen 1: implications for EBV-mediated immortalization V Saridakis, Y Sheng, F Sarkari, MN Holowaty, K Shire, T Nguyen, ... Molecular cell 18 (1), 25-36, 2005 | 437 | 2005 |
| Molecular recognition of p53 and MDM2 by USP7/HAUSP Y Sheng, V Saridakis, F Sarkari, S Duan, T Wu, CH Arrowsmith, ... Nature structural & molecular biology 13 (3), 285-291, 2006 | 364 | 2006 |
| Protein interaction domains of the ubiquitin-specific protease, USP7/HAUSP MN Holowaty, Y Sheng, T Nguyen, C Arrowsmith, L Frappier Journal of Biological Chemistry 278 (48), 47753-47761, 2003 | 215 | 2003 |
| System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes W Zhang, KP Wu, MA Sartori, HB Kamadurai, A Ordureau, C Jiang, ... Molecular cell 62 (1), 121-136, 2016 | 177 | 2016 |
| EBNA1-mediated recruitment of a histone H2B deubiquitylating complex to the Epstein-Barr virus latent origin of DNA replication F Sarkari, T Sanchez-Alcaraz, S Wang, MN Holowaty, Y Sheng, ... PLoS pathogens 5 (10), e1000624, 2009 | 162 | 2009 |
| A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen Y Sheng, JH Hong, R Doherty, T Srikumar, J Shloush, GV Avvakumov, ... Molecular & Cellular Proteomics 11 (8), 329-341, 2012 | 136 | 2012 |
| Molecular basis of Pirh2-mediated p53 ubiquitylation Y Sheng, RC Laister, A Lemak, B Wu, E Tai, S Duan, J Lukin, ... Nature structural & molecular biology 15 (12), 1334-1342, 2008 | 120 | 2008 |
| A structure-based model of the c-Myc/Bin1 protein interaction shows alternative splicing of Bin1 and c-Myc phosphorylation are key binding determinants A Pineda-Lucena, CSW Ho, DYL Mao, Y Sheng, RC Laister, ... Journal of molecular biology 351 (1), 182-194, 2005 | 115 | 2005 |
| Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface A Espinosa, J Hennig, A Ambrosi, M Anandapadmanaban, MS Abelius, ... Journal of Biological Chemistry 286 (42), 36478-36491, 2011 | 96 | 2011 |
| Role of Pirh2 in mediating the regulation of p53 and c-Myc A Hakem, M Bohgaki, B Lemmers, E Tai, L Salmena, E Matysiak-Zablocki, ... PLoS genetics 7 (11), e1002360, 2011 | 82 | 2011 |
| The E3 ubiquitin ligase Mule acts through the ATM–p53 axis to maintain B lymphocyte homeostasis Z Hao, GS Duncan, YW Su, WY Li, J Silvester, C Hong, H You, D Brenner, ... Journal of Experimental Medicine 209 (1), 173-186, 2012 | 74 | 2012 |
| CUL7 is a novel antiapoptotic oncogene SS Kim, M Shago, L Kaustov, PC Boutros, JW Clendening, Y Sheng, ... Cancer research 67 (20), 9616-9622, 2007 | 73 | 2007 |
| Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7 F Sarkari, A La Delfa, CH Arrowsmith, L Frappier, Y Sheng, V Saridakis Journal of molecular biology 402 (5), 825-837, 2010 | 65 | 2010 |
| Process analytical technologies–advances in bioprocess integration and future perspectives G Gerzon, Y Sheng, M Kirkitadze Journal of Pharmaceutical and Biomedical Analysis 207, 114379, 2022 | 64 | 2022 |
| Structural basis of E2–25K/UBB+ 1 interaction leading to proteasome inhibition and neurotoxicity S Ko, GB Kang, SM Song, JG Lee, DY Shin, JH Yun, Y Sheng, C Cheong, ... Journal of biological chemistry 285 (46), 36070-36080, 2010 | 61 | 2010 |
| The E3 ligase PIRH2 polyubiquitylates CHK2 and regulates its turnover M Bohgaki, A Hakem, MJ Halaby, T Bohgaki, Q Li, PA Bissey, J Shloush, ... Cell Death & Differentiation 20 (6), 812-822, 2013 | 60 | 2013 |
| Ubiquitin-specific protease 7 is a regulator of ubiquitin-conjugating enzyme UbE2E1 F Sarkari, K Wheaton, A La Delfa, M Mohamed, F Shaikh, R Khatun, ... Journal of Biological Chemistry 288 (23), 16975-16985, 2013 | 57 | 2013 |
| Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2 J Shloush, JE Vlassov, I Engson, S Duan, V Saridakis, S Dhe-Paganon, ... Journal of biological chemistry 286 (6), 4796-4808, 2011 | 56 | 2011 |
| E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling C Dominguez-Brauer, R Khatun, AJ Elia, KL Thu, P Ramachandran, ... Proceedings of the National Academy of Sciences 114 (7), E1148-E1157, 2017 | 54 | 2017 |
| Identification of Kaposi sarcoma herpesvirus (KSHV) vIRF1 protein as a novel interaction partner of human deubiquitinase USP7 S Chavoshi, O Egorova, IK Lacdao, S Farhadi, Y Sheng, V Saridakis Journal of Biological Chemistry 291 (12), 6281-6291, 2016 | 51 | 2016 |
