Beta cell differentiation during early human pancreas development K Piper, S Brickwood, LW Turnpenny, IT Cameron, SG Ball, DI Wilson, ... Journal of Endocrinology 181 (1), 11-24, 2004 | 408 | 2004 |
Phenotypic and functional analyses show stem cell-derived hepatocyte-like cells better mimic fetal rather than adult hepatocytes M Baxter, S Withey, S Harrison, CP Segeritz, F Zhang, R Atkinson-Dell, ... Journal of hepatology 62 (3), 581-589, 2015 | 391 | 2015 |
Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndrome T Hearn, GL Renforth, C Spalluto, NA Hanley, K Piper, S Brickwood, ... Nature genetics 31 (1), 79-83, 2002 | 363 | 2002 |
Development of the human pancreas from foregut to endocrine commitment RE Jennings, AA Berry, R Kirkwood-Wilson, NA Roberts, T Hearn, ... Diabetes 62 (10), 3514-3522, 2013 | 362 | 2013 |
In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development M Goto, KP Hanley, J Marcos, PJ Wood, S Wright, AD Postle, IT Cameron, ... The Journal of clinical investigation 116 (4), 953-960, 2006 | 279 | 2006 |
PAK proteins and YAP-1 signalling downstream of integrin beta-1 in myofibroblasts promote liver fibrosis K Martin, J Pritchett, J Llewellyn, AF Mullan, VS Athwal, R Dobie, ... Nature communications 7 (1), 12502, 2016 | 216 | 2016 |
Derivation of human embryonic germ cells: an alternative source of pluripotent stem cells L Turnpenny, S Brickwood, CM Spalluto, K Piper, IT Cameron, DI Wilson, ... Stem Cells 21 (5), 598-609, 2003 | 189 | 2003 |
Understanding the role of SOX9 in acquired diseases: lessons from development J Pritchett, V Athwal, N Roberts, NA Hanley, KP Hanley Trends in molecular medicine 17 (3), 166-174, 2011 | 172 | 2011 |
Proteome‐wide analyses of human hepatocytes during differentiation and dedifferentiation C Rowe, DT Gerrard, R Jenkins, A Berry, K Durkin, L Sundstrom, ... Hepatology 58 (2), 799-809, 2013 | 155 | 2013 |
Ectopic SOX9 mediates extracellular matrix deposition characteristic of organ fibrosis KP Hanley, F Oakley, S Sugden, DI Wilson, DA Mann, NA Hanley Journal of Biological Chemistry 283 (20), 14063-14071, 2008 | 130 | 2008 |
Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia K Piper, SG Ball, JW Keeling, S Mansoor, DI Wilson, NA Hanley Mechanisms of development 116 (1-2), 223-226, 2002 | 123 | 2002 |
Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans J Pritchett, E Harvey, V Athwal, A Berry, C Rowe, F Oakley, A Moles, ... Hepatology 56 (3), 1108-1116, 2012 | 115 | 2012 |
Evaluating human embryonic germ cells: concord and conflict as pluripotent stem cells L Turnpenny, CM Spalluto, RM Perrett, M O'Shea, KP Hanley, IT Cameron, ... Stem Cells 24 (2), 212-220, 2006 | 101 | 2006 |
The Diabetic Phenotype in HNF4A Mutation Carriers Is Moderated By the Expression of HNF4A Isoforms From the P1 Promoter During Fetal Development LW Harries, JM Locke, B Shields, NA Hanley, KP Hanley, A Steele, ... Diabetes 57 (6), 1745-1752, 2008 | 93 | 2008 |
Generating hepatic cell lineages from pluripotent stem cells for drug toxicity screening MA Baxter, C Rowe, J Alder, S Harrison, KP Hanley, BK Park, ... Stem cell research 5 (1), 4-22, 2010 | 86 | 2010 |
Residual lung abnormalities after COVID-19 hospitalization: interim analysis of the UKILD post–COVID-19 study I Stewart, J Jacob, PM George, PL Molyneaux, JC Porter, RJ Allen, ... American journal of respiratory and critical care medicine 207 (6), 693-703, 2023 | 76 | 2023 |
The window period of NEUROGENIN3 during human gestation RJ Salisbury, J Blaylock, AA Berry, RE Jennings, R De Krijger, ... Islets 6 (3), e954436, 2014 | 71 | 2014 |
An integrative transcriptomic atlas of organogenesis in human embryos DT Gerrard, AA Berry, RE Jennings, K Piper Hanley, N Bobola, ... elife 5, e15657, 2016 | 70 | 2016 |
The circadian clock protein REVERBα inhibits pulmonary fibrosis development PS Cunningham, P Meijer, A Nazgiewicz, SG Anderson, LA Borthwick, ... Proceedings of the National Academy of Sciences 117 (2), 1139-1147, 2020 | 66 | 2020 |
Beta-cell differentiation during human development does not rely on nestin-positive precursors: implications for stem cell-derived replacement therapy K Piper, SG Ball, LW Turnpenny, S Brickwood, DI Wilson, NA Hanley Diabetologia 45, 1045-1047, 2002 | 62 | 2002 |