| Structural basis for substrate specificities of cellular deoxyribonucleoside kinases K Johansson, S Ramaswamy, C Ljungcrantz, W Knecht, J Piškur, ... Nature structural biology 8 (7), 616-620, 2001 | 166 | 2001 |
| Horizontal gene transfer promoted evolution of the ability to propagate under anaerobic conditions in yeasts Z Gojković, W Knecht, E Zameitat, J Warneboldt, JB Coutelis, Y Pynyaha, ... Molecular Genetics and Genomics 271, 387-393, 2004 | 157 | 2004 |
| Requirements for the mitochondrial import and localization of dihydroorotate dehydrogenase J Rawls, W Knecht, K Diekert, R Lill, M Löffler European Journal of Biochemistry 267 (7), 2079-2087, 2000 | 149 | 2000 |
| Trypsin IV or mesotrypsin and p23 cleave protease-activated receptors 1 and 2 to induce inflammation and hyperalgesia W Knecht, GS Cottrell, S Amadesi, J Mohlin, A Skaregarde, K Gedda, ... Journal of Biological Chemistry 282 (36), 26089-26100, 2007 | 124 | 2007 |
| Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives W Knecht, M Löffler Biochemical pharmacology 56 (9), 1259-1264, 1998 | 115 | 1998 |
| Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid W Knecht, J Henseling, M Löffler Chemico-biological interactions 124 (1), 61-76, 2000 | 113 | 2000 |
| Functional expression of a multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster and its C-terminal deletion mutants B Munch-Petersen, W Knecht, C Lenz, L Søndergaard, J Piškur Journal of biological chemistry 275 (9), 6673-6679, 2000 | 108 | 2000 |
| Functional expression of a fragment of human dihydroorotate dehydrogenase by means of the baculovirus expression vector system, and kinetic investigation of the purified … W Knecht, U Bergjohann, S Gonski, B Kirschbaum, M Lóffler European journal of biochemistry 240 (1), 292-301, 1996 | 104 | 1996 |
| Human subtilase SKI-1/S1P is a master regulator of the HCV Lifecycle and a potential host cell target for developing indirect-acting antiviral agents AD Olmstead, W Knecht, I Lazarov, SB Dixit, F Jean PLoS pathogens 8 (1), e1002468, 2012 | 98 | 2012 |
| A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines W Knecht, MPB Sandrini, K Johansson, H Eklund, B Munch‐Petersen, ... The EMBO journal, 2002 | 73 | 2002 |
| Recombinant expression of N‐terminal truncated mutants of the membrane bound mouse, rat and human flavoenzyme dihydroorotate dehydrogenase: A versatile tool to rate inhibitor … A Ullrich, W Knecht, M Fries, M Löffler European Journal of Biochemistry 268 (6), 1861-1868, 2001 | 63 | 2001 |
| Application of optical biosensors in small-molecule screening activities S Geschwindner, JF Carlsson, W Knecht Sensors 12 (4), 4311-4323, 2012 | 60 | 2012 |
| Expression, purification, and characterization of histidine-tagged rat and human flavoenzyme dihydroorotate dehydrogenase B Bader, W Knecht, M Fries, M Löffler Protein expression and purification 13 (3), 414-422, 1998 | 59 | 1998 |
| Protease-activated receptor 2, dipeptidyl peptidase I, and proteases mediate Clostridium difficile toxin A enteritis GS Cottrell, S Amadesi, S Pikios, E Camerer, JA Willardsen, BR Murphy, ... Gastroenterology 132 (7), 2422-2437, 2007 | 58 | 2007 |
| Identification of residues involved in the specificity and regulation of the highly efficient multisubstrate deoxyribonucleoside kinase from Drosophila melanogaster W Knecht, B Munch-Petersen, J Piškur Journal of molecular biology 301 (4), 827-837, 2000 | 56 | 2000 |
| Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design O Fjellström, S Akkaya, HG Beisel, PO Eriksson, K Erixon, D Gustafsson, ... PLoS One 10 (1), e0113705, 2015 | 54 | 2015 |
| Deoxyribonucleoside kinases belonging to the thymidine kinase 2 (TK2)-like group vary significantly in substrate specificity, kinetics and feed-back regulation W Knecht, GE Petersen, B Munch-Petersen, J Piškur Journal of molecular biology 315 (4), 529-540, 2002 | 54 | 2002 |
| Crystal structure of non-structural protein 10 from severe acute respiratory syndrome coronavirus-2 A Rogstam, M Nyblom, S Christensen, C Sele, VO Talibov, T Lindvall, ... International journal of molecular sciences 21 (19), 7375, 2020 | 53 | 2020 |
| Limited mutagenesis increases the stability of human carboxypeptidase U (TAFIa) and demonstrates the importance of CPU stability over proCPU concentration in down‐regulating … W Knecht, J Willemse, H Stenhamre, M Andersson, P Berntsson, ... The FEBS journal 273 (4), 778-792, 2006 | 49 | 2006 |
| Kazachstania gamospora and Wickerhamomyces subpelliculosus: Two alternative baker’s yeasts in the modern bakery N Zhou, AJ Schifferdecker, A Gamero, C Compagno, T Boekhout, J Piškur, ... International journal of food microbiology 250, 45-58, 2017 | 46 | 2017 |
