Chromatin-level regulation of biosynthetic gene clusters JW Bok, YM Chiang, E Szewczyk, Y Reyes-Dominguez, AD Davidson, ... Nature chemical biology 5 (7), 462-464, 2009 | 441 | 2009 |
A Gene Cluster Containing Two Fungal Polyketide Synthases Encodes the Biosynthetic Pathway for a Polyketide, Asperfuranone, in Aspergillus nidulans YM Chiang, E Szewczyk, AD Davidson, N Keller, BR Oakley, CCC Wang Journal of the American Chemical Society 131 (8), 2965-2970, 2009 | 361 | 2009 |
Advances in Aspergillus secondary metabolite research in the post-genomic era JF Sanchez, AD Somoza, NP Keller, CCC Wang Natural product reports 29 (3), 351-371, 2012 | 294 | 2012 |
Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli K Watanabe, K Hotta, AP Praseuth, K Koketsu, A Migita, CN Boddy, ... Nature chemical biology 2 (8), 423-428, 2006 | 279 | 2006 |
Two Separate Gene Clusters Encode the Biosynthetic Pathway for the Meroterpenoids Austinol and Dehydroaustinol in Aspergillus nidulans HC Lo, R Entwistle, CJ Guo, M Ahuja, E Szewczyk, JH Hung, YM Chiang, ... Journal of the American Chemical Society 134 (10), 4709-4720, 2012 | 266 | 2012 |
Recent advances in awakening silent biosynthetic gene clusters and linking orphan clusters to natural products in microorganisms YM Chiang, SL Chang, BR Oakley, CCC Wang Current opinion in chemical biology 15 (1), 137-143, 2011 | 253 | 2011 |
Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375. S2 cells CCC Wang, YM Chiang, SC Sung, YL Hsu, JK Chang, PL Kuo Cancer letters 259 (1), 82-98, 2008 | 243 | 2008 |
An efficient system for heterologous expression of secondary metabolite genes in Aspergillus nidulans YM Chiang, CE Oakley, M Ahuja, R Entwistle, A Schultz, SL Chang, ... Journal of the American Chemical Society 135 (20), 7720-7731, 2013 | 232 | 2013 |
Molecular genetic mining of the Aspergillus secondary metabolome: discovery of the emericellamide biosynthetic pathway YM Chiang, E Szewczyk, T Nayak, AD Davidson, JF Sanchez, HC Lo, ... Chemistry & biology 15 (6), 527-532, 2008 | 227 | 2008 |
Identification and Characterization of the Asperthecin Gene Cluster of Aspergillus nidulans E Szewczyk, YM Chiang, CE Oakley, AD Davidson, CCC Wang, ... Applied and environmental microbiology 74 (24), 7607-7612, 2008 | 205 | 2008 |
Prototype of an intertwined secondary-metabolite supercluster P Wiemann, CJ Guo, JM Palmer, R Sekonyela, CCC Wang, NP Keller Proceedings of the National Academy of Sciences 110 (42), 17065-17070, 2013 | 200 | 2013 |
Genome-Based Deletion Analysis Reveals the Prenyl Xanthone Biosynthesis Pathway in Aspergillus nidulans JF Sanchez, R Entwistle, JH Hung, J Yaegashi, S Jain, YM Chiang, ... Journal of the American Chemical Society 133 (11), 4010-4017, 2011 | 196 | 2011 |
Characterization of the Aspergillus nidulans Monodictyphenone Gene Cluster YM Chiang, E Szewczyk, AD Davidson, R Entwistle, NP Keller, ... Applied and environmental microbiology 76 (7), 2067-2074, 2010 | 195 | 2010 |
Biosynthesis of lovastatin analogs with a broadly specific acyltransferase X Xie, K Watanabe, WA Wojcicki, CCC Wang, Y Tang Chemistry & biology 13 (11), 1161-1169, 2006 | 193 | 2006 |
Illuminating the Diversity of Aromatic Polyketide Synthases in Aspergillus nidulans M Ahuja, YM Chiang, SL Chang, MB Praseuth, R Entwistle, JF Sanchez, ... Journal of the American Chemical Society 134 (19), 8212-8221, 2012 | 181 | 2012 |
Molecular genetic analysis of the orsellinic acid/F9775 gene cluster of Aspergillus nidulans JF Sanchez, YM Chiang, E Szewczyk, AD Davidson, M Ahuja, CE Oakley, ... Molecular Biosystems 6 (3), 587-593, 2010 | 159 | 2010 |
Biosynthesis of Yersiniabactin, a Complex Polyketide-Nonribosomal Peptide, Using Escherichia coli as a Heterologous Host BA Pfeifer, CCC Wang, CT Walsh, C Khosla Applied and environmental microbiology 69 (11), 6698-6702, 2003 | 155 | 2003 |
Development of Genetic Dereplication Strains in Aspergillus nidulans Results in the Discovery of Aspercryptin YM Chiang, M Ahuja, CE Oakley, R Entwistle, A Asokan, C Zutz, ... Angewandte Chemie International Edition 55 (5), 1662-1665, 2016 | 154 | 2016 |
Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans J Yaegashi, BR Oakley, CCC Wang Journal of Industrial Microbiology and Biotechnology 41 (2), 433-442, 2014 | 144 | 2014 |
Rosmarinic acid and baicalin epigenetically derepress peroxisomal proliferator‐activated receptor γ in hepatic stellate cells for their antifibrotic effect MD Yang, YM Chiang, R Higashiyama, K Asahina, DA Mann, J Mann, ... Hepatology 55 (4), 1271-1281, 2012 | 139 | 2012 |