Systems biology approach reveals that overflow metabolism of acetate in Escherichia coli is triggered by carbon catabolite repression of acetyl-CoA synthetase K Valgepea, K Adamberg, R Nahku, PJ Lahtvee, L Arike, R Vilu BMC systems biology 4, 1-13, 2010 | 232 | 2010 |
Comparison and applications of label-free absolute proteome quantification methods on Escherichia coli L Arike, K Valgepea, L Peil, R Nahku, K Adamberg, R Vilu Journal of proteomics 75 (17), 5437-5448, 2012 | 194 | 2012 |
Escherichia coli achieves faster growth by increasing catalytic and translation rates of proteins K Valgepea, K Adamberg, A Seiman, R Vilu Molecular BioSystems 9 (9), 2344-2358, 2013 | 157 | 2013 |
Proteome reallocation in Escherichia coli with increasing specific growth rate K Peebo, K Valgepea, A Maser, R Nahku, K Adamberg, R Vilu Molecular BioSystems 11 (4), 1184-1193, 2015 | 138 | 2015 |
Maintenance of ATP homeostasis triggers metabolic shifts in gas-fermenting acetogens K Valgepea, RSP Lemgruber, K Meaghan, RW Palfreyman, T Abdalla, ... Cell systems 4 (5), 505-515. e5, 2017 | 135 | 2017 |
H2 drives metabolic rearrangements in gas-fermenting Clostridium autoethanogenum K Valgepea, R de Souza Pinto Lemgruber, T Abdalla, S Binos, ... Biotechnology for biofuels 11, 1-15, 2018 | 110 | 2018 |
Arginine deiminase pathway provides ATP and boosts growth of the gas-fermenting acetogen Clostridium autoethanogenum K Valgepea, KQ Loi, JB Behrendorff, R de SP Lemgruber, M Plan, ... Metabolic engineering 41, 202-211, 2017 | 109 | 2017 |
Enhancing CO2-Valorization Using Clostridium autoethanogenum for Sustainable Fuel and Chemicals Production JK Heffernan, K Valgepea, R de Souza Pinto Lemgruber, I Casini, M Plan, ... Frontiers in Bioengineering and Biotechnology 8, 204, 2020 | 101 | 2020 |
Adaptive laboratory evolution of native methanol assimilation in Saccharomyces cerevisiae MI Espinosa, RA Gonzalez-Garcia, K Valgepea, MR Plan, C Scott, ... Nature Communications 11 (1), 5564, 2020 | 84 | 2020 |
Specific growth rate dependent transcriptome profiling of Escherichia coli K12 MG1655 in accelerostat cultures R Nahku, K Valgepea, PJ Lahtvee, S Erm, K Abner, K Adamberg, R Vilu Journal of biotechnology 145 (1), 60-65, 2010 | 79 | 2010 |
Systems-level engineering and characterisation of Clostridium autoethanogenum through heterologous production of poly-3-hydroxybutyrate (PHB) RSP Lemgruber, K Valgepea, R Tappel, JB Behrendorff, RW Palfreyman, ... Metabolic engineering 53, 14-23, 2019 | 77 | 2019 |
Redox controls metabolic robustness in the gas-fermenting acetogen Clostridium autoethanogenum V Mahamkali, K Valgepea, R de Souza Pinto Lemgruber, M Plan, ... Proceedings of the National Academy of Sciences 117 (23), 13168-13175, 2020 | 59 | 2020 |
Advances in systems metabolic engineering of autotrophic carbon oxide-fixing biocatalysts towards a circular economy M Pavan, K Reinmets, S Garg, AP Mueller, E Marcellin, M Köpke, ... Metabolic Engineering 71, 117-141, 2022 | 49 | 2022 |
Decrease of energy spilling in Escherichia coli continuous cultures with rising specific growth rate and carbon wasting K Valgepea, K Adamberg, R Vilu BMC systems biology 5, 1-11, 2011 | 48 | 2011 |
Advanced continuous cultivation methods for systems microbiology K Adamberg, K Valgepea, R Vilu Microbiology 161 (9), 1707-1719, 2015 | 47 | 2015 |
Coordinated activation of PTA-ACS and TCA cycles strongly reduces overflow metabolism of acetate in Escherichia coli K Peebo, K Valgepea, R Nahku, G Riis, M Õun, K Adamberg, R Vilu Applied microbiology and biotechnology 98, 5131-5143, 2014 | 40 | 2014 |
Large expert-curated database for benchmarking document similarity detection in biomedical literature search P Brown, Y Zhou Database 2019, baz085, 2019 | 34 | 2019 |
Lean-proteome strains–next step in metabolic engineering K Valgepea, K Peebo, K Adamberg, R Vilu Frontiers in bioengineering and biotechnology 3, 11, 2015 | 25 | 2015 |
Absolute Proteome Quantification in the Gas-Fermenting Acetogen Clostridium autoethanogenum K Valgepea, G Talbo, N Takemori, A Takemori, C Ludwig, V Mahamkali, ... Msystems 7 (2), e00026-22, 2022 | 21 | 2022 |
Stock culture heterogeneity rather than new mutational variation complicates short-term cell physiology studies of Escherichia coli K-12 MG1655 in continuous culture. R Nahku, K Peebo, K Valgepea, JE Barrick, K Adamberg, R Vilu Microbiology 157 (9), 2604-2610, 2011 | 20 | 2011 |