Use of a Robust Dehydrogenase from an Archael Hyperthermophile in Asymmetric Catalysis−Dynamic Reductive Kinetic Resolution Entry into (S)-Profens JA Friest, Y Maezato, S Broussy, P Blum, DB Berkowitz Journal of the American Chemical Society 132 (17), 5930-5931, 2010 | 114 | 2010 |
Enantioselective, ketoreductase-based entry into pharmaceutical building blocks: ethanol as tunable nicotinamide reductant S Broussy, RW Cheloha, DB Berkowitz Organic letters 11 (2), 305-308, 2009 | 100 | 2009 |
Mn(III) Pyrophosphate as an Efficient Tool for Studying the Mode of Action of Isoniazid on the InhA Protein of Mycobacterium tuberculosis M Nguyen, A Quémard, S Broussy, J Bernadou, B Meunier Antimicrobial agents and chemotherapy 46 (7), 2137-2144, 2002 | 100 | 2002 |
The First Chemical Synthesis of the Core Structure of the Benzoylhydrazine−NAD Adduct, a Competitive Inhibitor of the Mycobacterium tuberculosis Enoyl Reductase S Broussy, V Bernardes-Génisson, A Quémard, B Meunier, J Bernadou The Journal of Organic Chemistry 70 (25), 10502-10510, 2005 | 66 | 2005 |
Biochemical mechanism and biological effects of the inhibition of silent information regulator 1 (SIRT1) by EX-527 (SEN0014196 or selisistat) S Broussy, H Laaroussi, M Vidal Journal of enzyme inhibition and medicinal chemistry 35 (1), 1124-1136, 2020 | 47 | 2020 |
1H and 13C NMR Characterization of Hemiamidal Isoniazid‐NAD(H) Adducts as Possible Inhibitors Of InhA Reductase of Mycobacterium tuberculosis S Broussy, Y Coppel, M Nguyen, J Bernadou, B Meunier Chemistry–A European Journal 9 (9), 2034-2038, 2003 | 45 | 2003 |
Guanine oxidation by electron transfer: one‐versus two‐electron oxidation mechanism A Kupan, A Saulière, S Broussy, C Seguy, G Pratviel, B Meunier ChemBioChem 7 (1), 125-133, 2006 | 38 | 2006 |
Combinatorial Catalysis Assisted by a Visible Enzymatic Beacon in Real Time: New Synthetically Versatile (Pseudo) Halometalation/Carbocyclizations JA Friest, S Broussy, WJ Chung, DB Berkowitz Angewandte Chemie (International ed. in English) 50 (38), 8895, 2011 | 34 | 2011 |
Isolation, characterization, antioxidant activity, and protein-precipitating capacity of the hydrolyzable tannin punicalagin from pomegranate yellow peel (Punica granatum) B Oudane, D Boudemagh, M Bounekhel, W Sobhi, M Vidal, S Broussy Journal of Molecular Structure 1156, 390-396, 2018 | 33 | 2018 |
Molecular docking, synthesis and biological evaluation of Vascular Endothelial Growth Factor (VEGF) B based peptide as antiangiogenic agent targeting the second domain of the … A Sadremomtaz, AM Ali, F Jouyandeh, S Balalaie, R Navari, S Broussy, ... Signal transduction and targeted therapy 5 (1), 76, 2020 | 23 | 2020 |
Design and synthesis of C-terminal modified cyclic peptides as VEGFR1 antagonists L Wang, N Gagey-Eilstein, S Broussy, M Reille-Seroussi, F Huguenot, ... Molecules 19 (10), 15391-15407, 2014 | 20 | 2014 |
1 H and 13C NMR characterization of pyridinium-type isoniazid–NAD adducts as possible inhibitors of InhA reductase of Mycobacterium tuberculosis S Broussy, V Bernardes-Génisson, Y Coppel, A Quémard, J Bernadou, ... Organic & Biomolecular Chemistry 3 (4), 670-673, 2005 | 20 | 2005 |
Studies on the 4-benzoylpyridine-3-carboxamide entity as a fragment model of the Isoniazid–NAD adduct S Broussy, V Bernardes-Génisson, H Gornitzka, J Bernadou, B Meunier Organic & Biomolecular Chemistry 3 (4), 666-669, 2005 | 20 | 2005 |
Identification of peptidic antagonists of vascular endothelial growth factor receptor 1 by scanning the binding epitopes of its ligands L Wang, L Zhou, M Reille-Seroussi, N Gagey-Eilstein, S Broussy, T Zhang, ... Journal of medicinal chemistry 60 (15), 6598-6606, 2017 | 19 | 2017 |
Vascular endothelial growth factor peptide ligands explored by competition assay and isothermal titration calorimetry M Reille-Seroussi, JF Gaucher, C Desole, N Gagey-Eilstein, F Brachet, ... Biochemistry 54 (33), 5147-5156, 2015 | 19 | 2015 |
A structural overview of vascular endothelial growth factors pharmacological ligands: from macromolecules to designed peptidomimetics X Ye, JF Gaucher, M Vidal, S Broussy Molecules 26 (22), 6759, 2021 | 15 | 2021 |
Biophysical studies of the induced dimerization of human VEGF receptor 1 binding domain by divalent metals competing with VEGF-A JF Gaucher, M Reille-Seroussi, N Gagey-Eilstein, S Broussy, P Coric, ... PLoS One 11 (12), e0167755, 2016 | 14 | 2016 |
Solid phase synthesis of highly substituted tetrahydropyrans by tandem ene-reaction/intramolecular sakurai cyclization S Broussy, H Waldmann Journal of Combinatorial Chemistry 9 (6), 1138-1143, 2007 | 14 | 2007 |
A Flexible Route Towards Five‐Membered Ring Imino Sugars and Their Novel 2‐Deoxy‐2‐fluoro Analogues T Ayad, Y Génisson, S Broussy, M Baltas, L Gorrichon European Journal of Organic Chemistry 2003 (15), 2903-2910, 2003 | 14 | 2003 |
Synthesis of indole inhibitors of silent information regulator 1 (SIRT1), and their evaluation as cytotoxic agents H Laaroussi, Y Ding, Y Teng, P Deschamps, M Vidal, P Yu, S Broussy European Journal of Medicinal Chemistry 202, 112561, 2020 | 13 | 2020 |