Lycorine, the main phenanthridine Amaryllidaceae alkaloid, exhibits significant antitumor activity in cancer cells that display resistance to proapoptotic stimuli: an … D Lamoral-Theys, A Andolfi, G Van Goietsenoven, A Cimmino, B Le Calvé, ... Journal of medicinal chemistry 52 (20), 6244-6256, 2009 | 306 | 2009 |
Lactose characteristics and the generation of the aerosol G Pilcer, N Wauthoz, K Amighi Advanced drug delivery reviews 64 (3), 233-256, 2012 | 257 | 2012 |
Ethnopharmacology of Mangifera indica L. bark and pharmacological studies of its main C-glucosylxanthone, mangiferin N Wauthoz, A Balde, ES Balde, M Van Damme, P Duez International Journal of Biomedical and Pharmaceutical Sciences 1 (2), 112-119, 2007 | 218 | 2007 |
Formulations for intranasal delivery of pharmacological agents to combat brain disease: a new opportunity to tackle GBM? M Van Woensel, N Wauthoz, R Rosière, K Amighi, V Mathieu, F Lefranc, ... Cancers 5 (3), 1020-1048, 2013 | 176 | 2013 |
Development of siRNA-loaded chitosan nanoparticles targeting Galectin-1 for the treatment of glioblastoma multiforme via intranasal administration M Van Woensel, N Wauthoz, R Rosière, V Mathieu, R Kiss, F Lefranc, ... Journal of Controlled Release 227, 71-81, 2016 | 158 | 2016 |
New folate-grafted chitosan derivative to improve delivery of paclitaxel-loaded solid lipid nanoparticles for lung tumor therapy by inhalation R Rosiere, M Van Woensel, M Gelbcke, V Mathieu, J Hecq, T Mathivet, ... Molecular pharmaceutics 15 (3), 899-910, 2018 | 139 | 2018 |
Sensitization of glioblastoma tumor micro-environment to chemo-and immunotherapy by Galectin-1 intranasal knock-down strategy M Van Woensel, T Mathivet, N Wauthoz, R Rosière, AD Garg, P Agostinis, ... Scientific Reports 7 (1), 1217, 2017 | 128 | 2017 |
How to characterize a nasal product. The state of the art of in vitro and ex vivo specific methods L Salade, N Wauthoz, J Goole, K Amighi International journal of pharmaceutics 561, 47-65, 2019 | 72 | 2019 |
Solid dispersions of itraconazole for inhalation with enhanced dissolution, solubility and dispersion properties C Duret, N Wauthoz, T Sebti, F Vanderbist, K Amighi International journal of pharmaceutics 428 (1-2), 103-113, 2012 | 72 | 2012 |
Phospholipids in pulmonary drug delivery N Wauthoz, K Amighi European journal of lipid science and technology 116 (9), 1114-1128, 2014 | 71 | 2014 |
New inhalation-optimized itraconazole nanoparticle-based dry powders for the treatment of invasive pulmonary aspergillosis C Duret, N Wauthoz, T Sebti, F Vanderbist, K Amighi International journal of nanomedicine, 5475-5489, 2012 | 65 | 2012 |
In vitro and in vivo evaluation of a dry powder endotracheal insufflator device for use in dose-dependent preclinical studies in mice C Duret, N Wauthoz, R Merlos, J Goole, C Maris, I Roland, T Sebti, ... European journal of pharmaceutics and biopharmaceutics 81 (3), 627-634, 2012 | 64 | 2012 |
Chitosan-coated liposome dry-powder formulations loaded with ghrelin for nose-to-brain delivery L Salade, N Wauthoz, M Vermeersch, K Amighi, J Goole European Journal of Pharmaceutics and Biopharmaceutics 129, 257-266, 2018 | 59 | 2018 |
Development of controlled-release cisplatin dry powders for inhalation against lung cancers V Levet, R Rosière, R Merlos, L Fusaro, G Berger, K Amighi, N Wauthoz International journal of pharmaceutics 515 (1-2), 209-220, 2016 | 58 | 2016 |
In vivo assessment of temozolomide local delivery for lung cancer inhalation therapy N Wauthoz, P Deleuze, J Hecq, I Roland, S Saussez, I Adanja, O Debeir, ... European journal of pharmaceutical sciences 39 (5), 402-411, 2010 | 54 | 2010 |
Simple di-and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli D Lamoral-Theys, L Pottier, F Kerff, F Dufrasne, F Proutière, N Wauthoz, ... Bioorganic & medicinal chemistry 18 (11), 3823-3833, 2010 | 52 | 2010 |
Temozolomide-based dry powder formulations for lung tumor-related inhalation treatment N Wauthoz, P Deleuze, A Saumet, C Duret, R Kiss, K Amighi Pharmaceutical research 28, 762-775, 2011 | 49 | 2011 |
The position of inhaled chemotherapy in the care of patients with lung tumors: clinical feasibility and indications according to recent pharmaceutical progresses R Rosière, T Berghmans, P De Vuyst, K Amighi, N Wauthoz Cancers 11 (3), 329, 2019 | 48 | 2019 |
Development of coated liposomes loaded with ghrelin for nose-to-brain delivery for the treatment of cachexia L Salade, N Wauthoz, M Deleu, M Vermeersch, C De Vriese, K Amighi, ... International Journal of Nanomedicine, 8531-8543, 2017 | 46 | 2017 |
Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity M Bury, E Novo-Uzal, A Andolfi, S Cimini, N Wauthoz, P Heffeter, ... International Journal of Oncology 43 (2), 575-585, 2013 | 43 | 2013 |