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Landscape of somatic mutations in 560 breast cancer whole-genome sequences S Nik-Zainal, H Davies, J Staaf, M Ramakrishna, D Glodzik, X Zou, ... Nature 534 (7605), 47-54, 2016 | 2203 | 2016 |
Mutational processes molding the genomes of 21 breast cancers S Nik-Zainal, LB Alexandrov, DC Wedge, P Van Loo, CD Greenman, ... Cell 149 (5), 979-993, 2012 | 2077 | 2012 |
Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 1754* | 2020 |
The life history of 21 breast cancers S Nik-Zainal, P Van Loo, DC Wedge, LB Alexandrov, CD Greenman, ... Cell 149 (5), 994-1007, 2012 | 1559 | 2012 |
HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures H Davies, D Glodzik, S Morganella, LR Yates, J Staaf, X Zou, ... Nature medicine 23 (4), 517-525, 2017 | 943 | 2017 |
Subclonal diversification of primary breast cancer revealed by multiregion sequencing LR Yates, M Gerstung, S Knappskog, C Desmedt, G Gundem, P Van Loo, ... Nature medicine 21 (7), 751-759, 2015 | 840 | 2015 |
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue CS Cooper, R Eeles, DC Wedge, P Van Loo, G Gundem, LB Alexandrov, ... Nature genetics 47 (4), 367-372, 2015 | 473 | 2015 |
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes JMC Tubio, Y Li, YS Ju, I Martincorena, SL Cooke, M Tojo, G Gundem, ... Science 345 (6196), 1251343, 2014 | 438 | 2014 |
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia E Papaemmanuil, I Rapado, Y Li, NE Potter, DC Wedge, J Tubio, ... Nature genetics 46 (2), 116-125, 2014 | 411 | 2014 |
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer YS Ju, LB Alexandrov, M Gerstung, I Martincorena, S Nik-Zainal, ... elife 3, e02935, 2014 | 404 | 2014 |
Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers A Shlien, BB Campbell, R De Borja, LB Alexandrov, D Merico, D Wedge, ... Nature genetics 47 (3), 257-262, 2015 | 376 | 2015 |
No evidence of clonal somatic genetic alterations in cancer-associated fibroblasts from human breast and ovarian carcinomas W Qiu, M Hu, A Sridhar, K Opeskin, S Fox, M Shipitsin, M Trivett, ... Nature genetics 40 (5), 650-655, 2008 | 329 | 2008 |
Association of a germline copy number polymorphism of APOBEC3A and APOBEC3B with burden of putative APOBEC-dependent mutations in breast cancer S Nik-Zainal, DC Wedge, LB Alexandrov, M Petljak, AP Butler, N Bolli, ... Nature genetics 46 (5), 487-491, 2014 | 308 | 2014 |
Recurrent PTPRB and PLCG1 mutations in angiosarcoma S Behjati, PS Tarpey, H Sheldon, I Martincorena, P Van Loo, G Gundem, ... Nature genetics 46 (4), 376-379, 2014 | 300 | 2014 |
Somatic mutations reveal asymmetric cellular dynamics in the early human embryo YS Ju, I Martincorena, M Gerstung, M Petljak, LB Alexandrov, R Rahbari, ... Nature 543 (7647), 714-718, 2017 | 287 | 2017 |
Comprehensive identification of RNA–protein interactions in any organism using orthogonal organic phase separation (OOPS) RML Queiroz, T Smith, E Villanueva, M Marti-Solano, M Monti, M Pizzinga, ... Nature biotechnology 37 (2), 169-178, 2019 | 285 | 2019 |
The topography of mutational processes in breast cancer genomes S Morganella, LB Alexandrov, D Glodzik, X Zou, H Davies, J Staaf, ... Nature communications 7 (1), 11383, 2016 | 278 | 2016 |
Mutational signatures of ionizing radiation in second malignancies S Behjati, G Gundem, DC Wedge, ND Roberts, PS Tarpey, SL Cooke, ... Nature communications 7 (1), 1-8, 2016 | 264 | 2016 |
Identification of candidate growth promoting genes in ovarian cancer through integrated copy number and expression analysis M Ramakrishna, LH Williams, SE Boyle, JL Bearfoot, A Sridhar, TP Speed, ... PloS one 5 (4), e9983, 2010 | 162 | 2010 |