Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene LC Papadopoulou, CM Sue, MM Davidson, K Tanji, I Nishino, JE Sadlock, ... Nature genetics 23 (3), 333-337, 1999 | 688 | 1999 |
CAR T-cell therapy: a new era in cancer immunotherapy AN Miliotou, LC Papadopoulou Current pharmaceutical biotechnology 19 (1), 5-18, 2018 | 545 | 2018 |
Heme as key regulator of major mammalian cellular functions: molecular, cellular, and pharmacological aspects AS Tsiftsoglou, AI Tsamadou, LC Papadopoulou Pharmacology & therapeutics 111 (2), 327-345, 2006 | 355 | 2006 |
Differential features of patients with mutations in two COX assembly genes, SURF‐1 and SCO2 CM Sue, C Karadimas, N Checcarelli, K Tanji, LC Papadopoulou, ... Annals of neurology 47 (5), 589-595, 2000 | 155 | 2000 |
The fate of human sperm-derived mtDNA in somatic cells G Manfredi, D Thyagarajan, LC Papadopoulou, F Pallotti, EA Schon The American Journal of Human Genetics 61 (4), 953-960, 1997 | 135 | 1997 |
Structural and functional impairment of mitochondria in adriamycin-induced cardiomyopathy in mice: suppression of cytochrome c oxidase II gene expression LC Papadopoulou, G Theophilidis, GN Thomopoulos, AS Tsiftsoglou Biochemical pharmacology 57 (5), 481-489, 1999 | 117 | 1999 |
Effects of hemin on apoptosis, suppression of cytochrome c oxidase gene expression, and bone-marrow toxicity induced by doxorubicin (adriamycin) LC Papadopoulou, AS Tsiftsoglou Biochemical pharmacology 52 (5), 713-722, 1996 | 55 | 1996 |
Mitochondrial Cytochrome c Oxidase as a Target Site for Daunomycin in K-562 Cells and Heart Tissue LC Papadopoulou, AS Tsiftsoglou Cancer research 53 (5), 1072-1078, 1993 | 49 | 1993 |
Synthesis, characterization and biological evaluation of 99mTc/Re–tricarbonyl quinolone complexes TE Kydonaki, E Tsoukas, F Mendes, AG Hatzidimitriou, A Paulo, ... Journal of Inorganic Biochemistry 160, 94-105, 2016 | 42 | 2016 |
Human recombinant mutated forms of the mitochondrial COX assembly Sco2 protein differ from wild-type in physical state and copper binding capacity PF Foltopoulou, GA Zachariadis, AS Politou, AS Tsiftsoglou, ... Molecular genetics and metabolism 81 (3), 225-236, 2004 | 36 | 2004 |
Intracellular delivery of full length recombinant human mitochondrial L-Sco2 protein into the mitochondria of permanent cell lines and SCO2 deficient patient's primary cells PF Foltopoulou, AS Tsiftsoglou, ID Bonovolias, AT Ingendoh, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (6), 497-508, 2010 | 31 | 2010 |
In vitro-transcribed (IVT)-mRNA CAR therapy development AN Miliotou, LC Papadopoulou Chimeric Antigen Receptor T Cells: Development and Production, 87-117, 2020 | 30 | 2020 |
Organometallic rhenium tricarbonyl–enrofloxacin and–levofloxacin complexes: Synthesis, albumin-binding, DNA-interaction and cell viability studies CC Pagoni, VS Xylouri, GC Kaiafas, M Lazou, G Bompola, E Tsoukas, ... JBIC Journal of Biological Inorganic Chemistry 24, 609-619, 2019 | 25 | 2019 |
Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders AN Miliotou, IS Pappas, G Spyroulias, E Vlachaki, AS Tsiftsoglou, ... Molecular Therapy-Nucleic Acids 26, 694-710, 2021 | 23 | 2021 |
Tackling pharmacological response heterogeneity by PBPK modeling to advance precision medicine productivity of nanotechnology and genomics therapeutics IS Vizirianakis, AN Miliotou, GA Mystridis, EG Andriotis, II Andreadis, ... Expert Review of Precision Medicine and Drug Development 4 (3), 139-151, 2019 | 22 | 2019 |
Transduction of human recombinant proteins into mitochondria as a protein therapeutic approach for mitochondrial disorders LC Papadopoulou, AS Tsiftsoglou Pharmaceutical research 28, 2639-2656, 2011 | 22 | 2011 |
The potential role of cell penetrating peptides in the intracellular delivery of proteins for therapy of erythroid related disorders LC Papadopoulou, AS Tsiftsoglou Pharmaceuticals 6 (1), 32-53, 2013 | 20 | 2013 |
Differences in nuclear gene expression between cells containing monomer and dimer mitochondrial genomes KM Clark, TA Brown, MM Davidson, LC Papadopoulou, DA Clayton Gene 286 (1), 91-104, 2002 | 14 | 2002 |
In vivo biodistribution study of TAT-L-Sco2 fusion protein, developed as protein therapeutic for mitochondrial disorders attributed to SCO2 mutations GC Kaiafas, D Papagiannopoulou, ΑN Miliotou, AS Tsingotjidou, ... Molecular Genetics and Metabolism Reports 25, 100683, 2020 | 12 | 2020 |
Production and Transduction of a Human Recombinant β-Globin Chain into Proerythroid K-562 Cells To Replace Missing Endogenous β-Globin LC Papadopoulou, A Ingendoh-Tsakmakidis, CN Mpoutoureli, ... Molecular Pharmaceutics 15 (12), 5665-5677, 2018 | 9 | 2018 |