| Poor accuracy and sustainability of the first‐step FIB4 EASL pathway for stratifying steatotic liver disease risk in the general population A De Vincentis, F Tavaglione, S Namba, M Kanai, Y Okada, Y Kamatani, ... Alimentary Pharmacology & Therapeutics 59 (11), 1402-1412, 2024 | | 2024 |
| Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles S Sakaue, K Weinand, S Isaac, KK Dey, K Jagadeesh, M Kanai, ... Nature Genetics, 1-12, 2024 | 8 | 2024 |
| Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation VL Faro, A Bhattacharya, W Zhou, D Zhou, Y Wang, K Läll, M Kanai, ... Cell Reports Medicine 5 (2), 2024 | 11* | 2024 |
| X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by … M Scholz, K Horn, J Pott, M Wuttke, A Kühnapfel, MK Nasr, H Kirsten, Y Li, ... Nature Communications 15 (1), 586, 2024 | 1 | 2024 |
| Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference X Meng, G Navoly, O Giannakopoulou, DF Levey, D Koller, GA Pathak, ... Nature Genetics, 1-12, 2024 | 11* | 2024 |
| A genomic mutational constraint map using variation in 76,156 human genomes S Chen, LC Francioli, JK Goodrich, RL Collins, M Kanai, Q Wang, J Alföldi, ... Nature 625 (7993), 92-100, 2024 | 239* | 2024 |
| Efficient and accurate mixed model association tool for single-cell eQTL analysis W Zhou, A Cuomo, A Xue, M Kanai, G Chau, C Krishna, RJ Xavier, ... medRxiv, 2024.05. 15.24307317, 2024 | | 2024 |
| MultiSuSiE improves multi-ancestry fine-mapping in All of Us whole-genome sequencing data J Rossen, H Shi, BJ Strober, MJ Zhang, M Kanai, ZR McCaw, L Liang, ... medRxiv, 2024.05. 13.24307291, 2024 | | 2024 |
| Functional dissection of complex and molecular trait variants at single nucleotide resolution L Siraj, RI Castro, H Dewey, S Kales, TTL Nguyen, M Kanai, D Berenzy, ... bioRxiv, 2024.05. 05.592437, 2024 | | 2024 |
| Pan-UK Biobank GWAS improves discovery, analysis of genetic architecture, and resolution into ancestry-enriched effects KJ Karczewski, R Gupta, M Kanai, W Lu, K Tsuo, Y Wang, RK Walters, ... medRxiv, 2024.03. 13.24303864, 2024 | 1 | 2024 |
| Improving fine-mapping by modeling infinitesimal effects R Cui, RA Elzur, M Kanai, JC Ulirsch, O Weissbrod, MJ Daly, BM Neale, ... Nature Genetics 56 (1), 162-169, 2024 | 14 | 2024 |
| Polygenic prediction across populations is influenced by ancestry, genetic architecture, and methodology Y Wang, M Kanai, T Tan, M Kamariza, K Tsuo, K Yuan, W Zhou, Y Okada, ... Cell Genomics 3 (10), 2023 | 6 | 2023 |
| eQTL Catalogue 2023: New datasets, X chromosome QTLs, and improved detection and visualisation of transcript-level QTLs N Kerimov, R Tambets, JD Hayhurst, I Rahu, P Kolberg, U Raudvere, ... PLoS genetics 19 (9), e1010932, 2023 | 4 | 2023 |
| A second update on mapping the human genetic architecture of COVID-19 M Kanai, SJ Andrews, M Cordioli, C Stevens, BM Neale, M Daly, A Ganna, ... Nature 621 (7977), E7-E26, 2023 | 15 | 2023 |
| A cross-trait genetic correlation study identified eight diseases and traits associated with psoriasis K Ogawa, LC Tsoi, H Tanaka, M Kanai, PE Stuart, RP Nair, Y Tanaka, ... The Journal of investigative dermatology 143 (9), 1813-1816. e2, 2023 | 2 | 2023 |
| Nuclear genetic control of mtDNA copy number and heteroplasmy in humans R Gupta, M Kanai, TJ Durham, K Tsuo, JG McCoy, AV Kotrys, W Zhou, ... Nature 620 (7975), 839-848, 2023 | 28 | 2023 |
| Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases EM Weeks, JC Ulirsch, NY Cheng, BL Trippe, RS Fine, J Miao, ... Nature Genetics 55 (8), 1267-1276, 2023 | 134 | 2023 |
| Leveraging fine-scale population structures for precision healthcare M Kanai Nature Medicine 29 (7), 1611-1612, 2023 | | 2023 |
| A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk B Jermy, K Läll, B Wolford, Y Wang, K Zguro, Y Cheng, M Kanai, S Kanoni, ... medRxiv, 2023.06. 12.23291186, 2023 | 2 | 2023 |
| Analysis of genetic dominance in the UK Biobank DS Palmer, W Zhou, L Abbott, EM Wigdor, N Baya, C Churchhouse, ... Science 379 (6639), 1341-1348, 2023 | 18 | 2023 |
