High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing CD Sago, MP Lokugamage, K Paunovska, DA Vanover, CM Monaco, ... Proceedings of the National Academy of Sciences 115 (42), E9944-E9952, 2018 | 260 | 2018 |
A direct comparison of in vitro and in vivo nucleic acid delivery mediated by hundreds of nanoparticles reveals a weak correlation K Paunovska, CD Sago, CM Monaco, WH Hudson, MG Castro, ... Nano letters 18 (3), 2148-2157, 2018 | 186 | 2018 |
Synthetic biomarkers: a twenty-first century path to early cancer detection GA Kwong, S Ghosh, L Gamboa, C Patriotis, S Srivastava, SN Bhatia Nature Reviews Cancer 21 (10), 655-668, 2021 | 129 | 2021 |
Analyzing 2000 in Vivo Drug Delivery Data Points Reveals Cholesterol Structure Impacts Nanoparticle Delivery K Paunovska, CJ Gil, MP Lokugamage, CD Sago, M Sato, GN Lando, ... ACS nano 12 (8), 8341-8349, 2018 | 121 | 2018 |
Enhanced intratumoural activity of CAR T cells engineered to produce immunomodulators under photothermal control IC Miller, A Zamat, LK Sun, H Phuengkham, AM Harris, L Gamboa, J Yang, ... Nature biomedical engineering 5 (11), 1348-1359, 2021 | 93 | 2021 |
Remote control of mammalian cells with heat-triggered gene switches and photothermal pulse trains IC Miller, M Gamboa Castro, J Maenza, JP Weis, GA Kwong ACS synthetic biology 7 (4), 1167-1173, 2018 | 53 | 2018 |
Augmented lipid-nanoparticle-mediated in vivo genome editing in the lungs and spleen by disrupting Cas9 activity in the liver CD Sago, MP Lokugamage, D Loughrey, KE Lindsay, R Hincapie, ... Nature biomedical engineering 6 (2), 157-167, 2022 | 45 | 2022 |
Heat-triggered remote control of CRISPR-dCas9 for tunable transcriptional modulation L Gamboa, EV Phung, H Li, JP Meyers, AC Hart, IC Miller, GA Kwong ACS chemical biology 15 (2), 533-542, 2020 | 29 | 2020 |
In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles FY Su, QH Zhao, SN Dahotre, L Gamboa, SS Bawage, AD Silva Trenkle, ... Science Advances 8 (8), eabm7950, 2022 | 27 | 2022 |
Mechanophenotyping of 3D multicellular clusters using displacement arrays of rendered tractions SE Leggett, M Patel, TM Valentin, L Gamboa, AS Khoo, EK Williams, ... Proceedings of the National Academy of Sciences 117 (11), 5655-5663, 2020 | 27 | 2020 |
Synthetic immunity by remote control L Gamboa, AH Zamat, GA Kwong Theranostics 10 (8), 3652, 2020 | 19 | 2020 |
Remote control of CAR T cell therapies by thermal targeting IC Miller, LK Sun, AM Harris, L Gamboa, A Zamat, GA Kwong BioRxiv, 2020.04. 26.062703, 2020 | 5 | 2020 |
Sensitizing solid tumors to CAR-mediated cytotoxicity using synthetic antigens L Gamboa, AH Zamat, D Vanover, CA Thiveaud, HE Peck, ... bioRxiv, 2021.12. 11.472238, 2021 | 3 | 2021 |
Deciphering Tumor Heterogeneity in Triple-Negative Breast Cancer: The Crucial Role of Dynamic Cell-Cell and Cell-Matrix Interactions S Leggett, I Wong, C Nelson, M Brennan, M Patel, C Franck, S Martinez, ... Bulletin of the American Physical Society, 2024 | | 2024 |
Synthetic Biomarker Platforms for Early Detection of Disease L Gamboa, SN Dahotre, BA Holt, QD Mac, FY Su, A Sivakumar, ... EMERGING TECHNOLOGIES IN BIOPHYSICAL SCIENCES: A WORLD SCIENTIFIC REFERENCE …, 2023 | | 2023 |