The E3 ubiquitin ligase Asb2β is downregulated in a mouse model of hypertrophic cardiomyopathy and targets desmin for proteasomal degradation T Thottakara, FW Friedrich, S Reischmann, S Braumann, S Schlossarek, ... Journal of molecular and cellular cardiology 87, 214-224, 2015 | 34 | 2015 |
A novel miRNA screen identifies miRNA-4454 as a candidate biomarker for ventricular fibrosis in patients with hypertrophic cardiomyopathy T Thottakara, N Lund, E Krämer, P Kirchhof, L Carrier, M Patten Biomolecules 11 (11), 1718, 2021 | 19 | 2021 |
Increased myocardial mass and attenuation of myocardial strain in professional male soccer players and competitive male triathletes J Starekova, T Thottakara, GK Lund, GH Welsch, FJ Brunner, ... The International Journal of Cardiovascular Imaging 36, 2187-2197, 2020 | 15 | 2020 |
Cytokine-mediated alterations of human cardiac fibroblast’s secretome H Bräuninger, T Thottakara, J Schön, S Voss, V Dhople, S Warnke, ... International Journal of Molecular Sciences 22 (22), 12262, 2021 | 10 | 2021 |
S100A4 as a target of the E3-ligase Asb2β and its effect on engineered heart tissue S Braumann, T Thottakara, S Stücker, S Reischmann-Düsener, E Krämer, ... Frontiers in Physiology 9, 1292, 2018 | 3 | 2018 |
Abstract P1141: Molecular Insights Into The Phenotypic Heterogeneity Observed In Two Different Murine Models Of Hypertrophic Cardiomyopathy (HCM) T Thottakara, CS Long, A Padmanabhan, J Olgin, MR Abraham Circulation Research 133 (Suppl_1), AP1141-AP1141, 2023 | 1 | 2023 |
The Cardiac Fibroblast in heart failure–an inflammatory cell T Thottakara, VM Dhople, S Voss, J Schoen, U Voelker, S Blankenberg, ... European Heart Journal 41 (Supplement_2), ehaa946. 3731, 2020 | 1 | 2020 |
Allele-specific dysregulation of lipid and energy metabolism in early-stage hypertrophic cardiomyopathy A Vaniya, A Karlstaedt, D Gulkok, T Thottakara, Y Liu, S Fan, H Eades, ... Journal of Molecular and Cellular Cardiology Plus 8, 100073, 2024 | | 2024 |
Single-nucleus RNA/ATAC-seq in early-stage HCM models predicts SWI/SNF-activation in mutant-myocytes, and allele-specific differences in fibroblasts T Thottakara, A Padmanabhan, T Tanriverdi, T Thambidurai, JA Diaz-Rg, ... bioRxiv, 2024 | | 2024 |
Single-nucleus RNA/ATAC-seq Reveals SWI/SNF complex activation and allele-specific non-myocyte activation in HCM mouse models T Thottakara, A Padmanabhan, T Tanriverdi, T Thambidurai, JA Diaz-RG, ... bioRxiv, 2024.04. 24.589078, 2024 | | 2024 |
Lipid metabolism drives allele-specific early-stage hypertrophic cardiomyopathy A Vaniya, A Karlstaedt, D Ates Gulkok, T Thottakara, Y Liu, S Fan, ... bioRxiv, 2023.11. 10.564562, 2023 | | 2023 |
Metabolic acidosis of surprising origin in a 61-year-old female patient TF Koyro, T Thottakara, TB Huber, S Harendza Der Internist 62, 549-554, 2021 | | 2021 |
Short-and Mid-Term Outcomes after Surgical Myectomy in Patients with Hypertrophic Obstructive Cardiomyopathy I Subbotina, M Patten, T Thottakara, H Reichenspurner, C Detter The Thoracic and Cardiovascular Surgeon 67 (S 01), DGTHG-V11, 2019 | | 2019 |
New Repair Technique of Systolic Anterior Motion (SAM) of Mitral Valve in Patient with Hypertrophic Obstructive Cardiomyopathy (HOCM): A Case Report I Subbotina, M Patten, T Thottakara, H Reichenspurner, C Detter The Thoracic and Cardiovascular Surgeon 67 (S 01), DGTHG-KV74, 2019 | | 2019 |
Die Ubiquitin E3 Ligase Asb2β ist in einem Mausmodell der hypertrophen Kardiomyopathie herunterreguliert und markiert Desmin für den proteasomalen Abbau: Asb2beta T Thottakara Universität Hamburg, 2016 | | 2016 |