State‐of‐the‐art in downstream processing of monoclonal antibodies: Process trends in design and validation PA Marichal‐Gallardo, MM Alvarez Biotechnology progress 28 (4), 899-916, 2012 | 197 | 2012 |
Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol P Marichal-Gallardo, MM Pieler, MW Wolff, U Reichl Journal of Chromatography A 1483, 110-119, 2017 | 69 | 2017 |
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG. PK2. 1 G Gränicher, J Coronel, A Pralow, P Marichal-Gallardo, M Wolff, E Rapp, ... Vaccine 37 (47), 7019-7028, 2019 | 39 | 2019 |
Single-use capture purification of adeno-associated viral gene transfer vectors by membrane-based steric exclusion chromatography P Marichal-Gallardo, K Börner, MM Pieler, V Sonntag-Buck, M Obr, ... Human Gene Therapy 32 (17-18), 959-974, 2021 | 34 | 2021 |
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity U Rand, SY Kupke, H Shkarlet, MD Hein, T Hirsch, P Marichal-Gallardo, ... Cells 10 (7), 1756, 2021 | 25 | 2021 |
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles MD Hein, P Arora, P Marichal-Gallardo, M Winkler, Y Genzel, S Pöhlmann, ... BMC biology 19 (1), 91, 2021 | 25 | 2021 |
OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential MD Hein, H Kollmus, P Marichal-Gallardo, S Püttker, D Benndorf, ... Applied microbiology and biotechnology 105, 129-146, 2021 | 25 | 2021 |
A high cell density perfusion process for Modified Vaccinia virus Ankara production: Process integration with inline DNA digestion and cost analysis G Gränicher, M Babakhani, S Göbel, I Jordan, P Marichal‐Gallardo, ... Biotechnology and Bioengineering 118 (12), 4720-4734, 2021 | 17 | 2021 |
Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells T Bissinger, Y Wu, P Marichal‐Gallardo, D Riedel, X Liu, Y Genzel, ... Biotechnology and Bioengineering 118 (10), 3996-4013, 2021 | 17 | 2021 |
Multi‐enzyme cascades for the in vitro synthesis of guanosine diphosphate L‐fucose R Mahour, P Marichal-Gallardo, T Rexer, U Reichl ChemCatChem, 2020 | 15 | 2020 |
Chromatographic purification of biological macromolecules by their capture on hydrophilic surfaces with the aid of non-ionic polymers P Marichal-Gallardo Otto-von-Guericke-Universität Magdeburg, 2019 | 7 | 2019 |
A baseline process for the production, recovery, and purification of bacterial influenza vaccine candidates PB Sánchez‐Arreola, S López‐Uriarte, PA Marichal‐Gallardo, ... Biotechnology progress 29 (4), 896-908, 2013 | 7 | 2013 |
Broad-spectrum antiviral activity of Influenza A defective interfering particles against respiratory syncytial, Yellow Fever, and Zika Virus replication in vitro L Pelz, E Piagnani, P Marsall, N Wynserski, MD Hein, P Marichal-Gallardo, ... Viruses 15 (9), 1872, 2023 | 5 | 2023 |
Purifying viruses with a sheet of paper: single-use steric exclusion chromatography as a capture platform for vaccine candidates P Marichal-Gallardo, AR Fortuna, Y Genzel, M Wolff, U Reichl | 5 | 2018 |
Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice T Dogra, L Pelz, JD Boehme, J Kuechler, O Kershaw, P Marichal-Gallardo, ... Scientific Reports 13 (1), 20936, 2023 | 2 | 2023 |
An inactivated SARS-CoV-2 vaccine induced cross-neutralizing persisting antibodies and protected against challenge in small animals A Offersgaard, CRD Hernandez, S Feng, P Marichal-Gallardo, ... Iscience 26 (2), 2023 | 2 | 2023 |
Method for the separation of virus compositions including depletion and purification thereof M Wolff, MM Pieler, U Reichl, P Marichal-gallardo US Patent 11,697,800, 2023 | 1 | 2023 |
Integrated production of an influenza A vaccine candidate with MDCK suspension cells T Bissinger, Y Wu, P Marichal-Gallardo, D Riedel, X Liu, Y Genzel, ... Authorea Preprints, 2021 | 1 | 2021 |
Antiviral activity of influenza A virus defective interfering particles against SARS-CoV-2 replication in vitro through stimulation of innate immunity. Cells. 2021; 10 (7): 1756 U Rand, SY Kupke, H Shkarlet, MD Hein, T Hirsch, P Marichal-Gallardo, ... s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | 1 | 2021 |
A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines P. Marichal-Gallardo, Y. Genzel, K. Börner, D. Grimm, Michael W. Wolff, U ... Advancing Manufacture of Cell and Gene Therapies VI, 2019 | 1 | 2019 |