Pericyte–fibroblast transition promotes tumor growth and metastasis K Hosaka, Y Yang, T Seki, C Fischer, O Dubey, E Fredlund, J Hartman, ... Proceedings of the National Academy of Sciences 113 (38), E5618-E5627, 2016 | 321 | 2016 |
PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells Y Xue, S Lim, Y Yang, Z Wang, LDE Jensen, EM Hedlund, P Andersson, ... Nature medicine 18 (1), 100-110, 2012 | 230 | 2012 |
Cancer lipid metabolism confers antiangiogenic drug resistance H Iwamoto, M Abe, Y Yang, D Cui, T Seki, M Nakamura, K Hosaka, S Lim, ... Cell Metabolism 28 (1), 104-117. e5, 2018 | 223 | 2018 |
TNFR1 mediates TNF-α-induced tumour lymphangiogenesis and metastasis by modulating VEGF-C-VEGFR3 signalling H Ji, R Cao, Y Yang, Y Zhang, H Iwamoto, S Lim, M Nakamura, ... Nature communications 5 (1), 4944, 2014 | 173 | 2014 |
VEGF-B promotes cancer metastasis through a VEGF-A–independent mechanism and serves as a marker of poor prognosis for cancer patients X Yang, Y Zhang, K Hosaka, P Andersson, J Wang, F Tholander, Z Cao, ... Proceedings of the National Academy of Sciences 112 (22), E2900-E2909, 2015 | 166 | 2015 |
The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages Y Yang, P Andersson, K Hosaka, Y Zhang, R Cao, H Iwamoto, X Yang, ... Nature communications 7 (1), 11385, 2016 | 153 | 2016 |
D-mannose facilitates immunotherapy and radiotherapy of triple-negative breast cancer via degradation of PD-L1 R Zhang, Y Yang, W Dong, M Lin, J He, X Zhang, T Tian, Y Yang, K Chen, ... Proceedings of the National Academy of Sciences 119 (8), e2114851119, 2022 | 151 | 2022 |
Tumour PDGF-BB expression levels determine dual effects of anti-PDGF drugs on vascular remodelling and metastasis K Hosaka, Y Yang, T Seki, M Nakamura, P Andersson, P Rouhi, X Yang, ... Nature communications 4 (1), 2129, 2013 | 133 | 2013 |
Anti-VEGF–and anti-VEGF receptor–induced vascular alteration in mouse healthy tissues Y Yang, Y Zhang, Z Cao, H Ji, X Yang, H Iwamoto, E Wahlberg, T Länne, ... Proceedings of the National Academy of Sciences 110 (29), 12018-12023, 2013 | 132 | 2013 |
The impact of VEGF on cancer metastasis and systemic disease Y Yang, Y Cao Seminars in Cancer Biology, 2022 | 119 | 2022 |
Inflammatory cell-derived CXCL3 promotes pancreatic cancer metastasis through a novel myofibroblast-hijacked cancer escape mechanism X Sun, X He, Y Zhang, K Hosaka, P Andersson, J Wu, J Wu, X Jing, Q Du, ... Gut 71 (1), 129-147, 2022 | 109 | 2022 |
Opposing effects of circadian clock genes bmal1 and period2 in regulation of VEGF-dependent angiogenesis in developing zebrafish LD Jensen, Z Cao, M Nakamura, Y Yang, L Bräutigam, P Andersson, ... Cell reports 2 (2), 231-241, 2012 | 107 | 2012 |
Discontinuation of anti-VEGF cancer therapy promotes metastasis through a liver revascularization mechanism Y Yang, Y Zhang, H Iwamoto, K Hosaka, T Seki, P Andersson, S Lim, ... Nature communications 7 (1), 12680, 2016 | 103 | 2016 |
Brown-fat-mediated tumour suppression by cold-altered global metabolism T Seki, Y Yang, X Sun, S Lim, S Xie, Z Guo, W Xiong, M Kuroda, ... Nature 608 (7922), 421-428, 2022 | 100 | 2022 |
Molecular mechanisms of IL-33–mediated stromal interactions in cancer metastasis P Andersson, Y Yang, K Hosaka, Y Zhang, C Fischer, H Braun, S Liu, ... JCI insight 3 (20), 2018 | 99 | 2018 |
Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat T Seki, K Hosaka, S Lim, C Fischer, J Honek, Y Yang, P Andersson, ... Nature Communications 7 (1), 12152, 2016 | 99 | 2016 |
Mouse corneal lymphangiogenesis model R Cao, S Lim, H Ji, Y Zhang, Y Yang, J Honek, EM Hedlund, Y Cao Nature protocols 6 (6), 817-826, 2011 | 90 | 2011 |
A zebrafish model discovers a novel mechanism of stromal fibroblast-mediated cancer metastasis C Liu, Y Zhang, S Lim, K Hosaka, Y Yang, T Pavlova, T Alkasalias, ... Clinical Cancer Research 23 (16), 4769-4779, 2017 | 85 | 2017 |
Therapeutic paradigm of dual targeting VEGF and PDGF for effectively treating FGF-2 off-target tumors K Hosaka, Y Yang, T Seki, Q Du, X Jing, X He, J Wu, Y Zhang, ... Nature communications 11 (1), 3704, 2020 | 72 | 2020 |
Crosstalk between Raf/MEK/ERK and PI3K/AKT in suppression of Bax conformational change by Grp75 under glucose deprivation conditions L Yang, W Guo, Q Zhang, H Li, X Liu, Y Yang, J Zuo, W Liu Journal of molecular biology 414 (5), 654-666, 2011 | 71 | 2011 |