The Hippo pathway and human cancer KF Harvey, X Zhang, DM Thomas Nature Reviews Cancer 13 (4), 246-257, 2013 | 1938 | 2013 |
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis KF Harvey, CM Pfleger, IK Hariharan Cell 114 (4), 457-467, 2003 | 1112 | 2003 |
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines N Tapon, KF Harvey, DW Bell, DCR Wahrer, TA Schiripo, DA Haber, ... Cell 110 (4), 467-478, 2002 | 980 | 2002 |
The Salvador–Warts–Hippo pathway—an emerging tumour-suppressor network K Harvey, N Tapon Nature Reviews Cancer 7 (3), 182-191, 2007 | 715 | 2007 |
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms NA Grzeschik, LM Parsons, ML Allott, KF Harvey, HE Richardson Current biology 20 (7), 573-581, 2010 | 402 | 2010 |
Fat cadherin modulates organ size in Drosophila via the Salvador/Warts/Hippo signaling pathway FC Bennett, KF Harvey Current Biology 16 (21), 2101-2110, 2006 | 356 | 2006 |
The Hippo pathway transcriptional co-activator, YAP, is an ovarian cancer oncogene X Zhang, J George, S Deb, JL Degoutin, EA Takano, SB Fox, DDL Bowtell, ... Oncogene 30 (25), 2810-2822, 2011 | 355 | 2011 |
Nedd4-like proteins: an emerging family of ubiquitin-protein ligases implicated in diverse cellular functions KF Harvey, S Kumar Trends in cell biology 9 (5), 166-169, 1999 | 269 | 1999 |
The sterile 20-like kinase Tao-1 controls tissue growth by regulating the Salvador-Warts-Hippo pathway CLC Poon, JI Lin, X Zhang, KF Harvey Developmental cell 21 (5), 896-906, 2011 | 227 | 2011 |
Upstream regulation of the hippo size control pathway FA Grusche, HE Richardson, KF Harvey Current Biology 20 (13), R574-R582, 2010 | 218 | 2010 |
cDNA cloning, expression analysis, and mapping of the MouseNedd4Gene S Kumar, KF Harvey, M Kinoshita, NG Copeland, M Noda, NA Jenkins Genomics 40 (3), 435-443, 1997 | 182 | 1997 |
The Nedd4-like protein KIAA0439 is a potential regulator of the epithelial sodium channel KF Harvey, A Dinudom, DI Cook, S Kumar Journal of Biological Chemistry 276 (11), 8597-8601, 2001 | 178 | 2001 |
Modularity in the Hippo signaling pathway M Sudol, KF Harvey Trends in biochemical sciences 35 (11), 627-633, 2010 | 177 | 2010 |
Nedd4 mediates control of an epithelial Na+ channel in salivary duct cells by cytosolic Na+ A Dinudom, KF Harvey, P Komwatana, JA Young, S Kumar, DI Cook Proceedings of the National Academy of Sciences 95 (12), 7169-7173, 1998 | 169 | 1998 |
The Hippo pathway effector YAP is a critical regulator of skeletal muscle fibre size KI Watt, BJ Turner, A Hagg, X Zhang, JR Davey, H Qian, C Beyer, ... Nature communications 6 (1), 6048, 2015 | 167 | 2015 |
All three WW domains of murine Nedd4 are involved in the regulation of epithelial sodium channels by intracellular Na+ KF Harvey, A Dinudom, P Komwatana, CN Jolliffe, ML Day, G Parasivam, ... Journal of Biological Chemistry 274 (18), 12525-12530, 1999 | 158 | 1999 |
A tumor suppressor activity of Drosophila Polycomb genes mediated by JAK-STAT signaling AK Classen, BD Bunker, KF Harvey, T Vaccari, D Bilder Nature genetics 41 (10), 1150-1155, 2009 | 157 | 2009 |
The Salvador/Warts/Hippo pathway controls regenerative tissue growth in Drosophila melanogaster FA Grusche, JL Degoutin, HE Richardson, KF Harvey Developmental biology 350 (2), 255-266, 2011 | 144 | 2011 |
Identification of multiple proteins expressed in murine embryos as binding partners for the WW domains of the ubiquitin-protein ligase Nedd4 CN JOLLIFFE, KF Harvey, BP Haines, G Parasivam, S Kumar Biochemical Journal 351 (3), 557-565, 2000 | 139 | 2000 |
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer SJ Vervoort, SA Welsh, JR Devlin, E Barbieri, DA Knight, S Offley, ... Cell 184 (12), 3143-3162. e32, 2021 | 131 | 2021 |