Structure–activity relationship studies of curcumin analogues JR Fuchs, B Pandit, D Bhasin, JP Etter, N Regan, D Abdelhamid, C Li, ... Bioorganic & medicinal chemistry letters 19 (7), 2065-2069, 2009 | 179 | 2009 |
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity MA Bill, JR Fuchs, C Li, J Yui, C Bakan, DM Benson, EB Schwartz, ... Molecular cancer 9, 1-12, 2010 | 146 | 2010 |
Tartaric acid-based amphiphilic macromolecules with ether linkages exhibit enhanced repression of oxidized low density lipoprotein uptake DS Abdelhamid, Y Zhang, DR Lewis, PV Moghe, WJ Welsh, KE Uhrich Biomaterials 53, 32-39, 2015 | 102 | 2015 |
Sugar-based amphiphilic polymers for biomedical applications: from nanocarriers to therapeutics L Gu, A Faig, D Abdelhamid, K Uhrich Accounts of chemical research 47 (10), 2867-2877, 2014 | 100 | 2014 |
New 1, 2, 4-triazole-Chalcone hybrids induce Caspase-3 dependent apoptosis in A549 human lung adenocarcinoma cells FF Ahmed, AA Abd El-Hafeez, SH Abbas, D Abdelhamid, M Abdel-Aziz European journal of medicinal chemistry 151, 705-722, 2018 | 82 | 2018 |
Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors TD Kim, JR Fuchs, E Schwartz, D Abdelhamid, J Etter, WL Berry, C Li, ... American journal of translational research 6 (3), 236, 2014 | 79 | 2014 |
Design and synthesis of novel quinoline/chalcone/1, 2, 4-triazole hybrids as potent antiproliferative agent targeting EGFR and BRAFV600E kinases AM Mohassab, HA Hassan, D Abdelhamid, AM Gouda, BGM Youssif, ... Bioorganic chemistry 106, 104510, 2021 | 71 | 2021 |
Synthesis, antiproliferative, anti-tubulin activity, and docking study of new 1, 2, 4-triazoles as potential combretastatin analogues M Mustafa, D Abdelhamid, ESMN Abdelhafez, MAA Ibrahim, ... European journal of medicinal chemistry 141, 293-305, 2017 | 60 | 2017 |
1, 3, 4-oxadiazole/chalcone hybrids: Design, synthesis, and inhibition of leukemia cell growth and EGFR, Src, IL-6 and STAT3 activities MAA Fathi, AA Abd El-Hafeez, D Abdelhamid, SH Abbas, MM Montano, ... Bioorganic chemistry 84, 150-163, 2019 | 59 | 2019 |
Novel quinoline incorporating 1, 2, 4-triazole/oxime hybrids: synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations AM Mohassab, HA Hassan, D Abdelhamid, M Abdel-Aziz, KN Dalby, ... Bioorganic chemistry 75, 242-259, 2017 | 51 | 2017 |
STAT3 transcription factor as target for anti-cancer therapy AM Mohassab, HA Hassan, D Abdelhamid, M Abdel-Aziz Pharmacological Reports 72, 1101-1124, 2020 | 50 | 2020 |
Athero-inflammatory nanotherapeutics: Ferulic acid-based poly (anhydride-ester) nanoparticles attenuate foam cell formation by regulating macrophage lipogenesis and reactive … RA Chmielowski, DS Abdelhamid, JJ Faig, LK Petersen, CR Gardner, ... Acta biomaterialia 57, 85-94, 2017 | 49 | 2017 |
Recent progress in biologically active indole hybrids: A mini review E Mahmoud, AM Hayallah, S Kovacic, D Abdelhamid, M Abdel-Aziz Pharmacological Reports 74 (4), 570-582, 2022 | 41 | 2022 |
Role of branching of hydrophilic domain on physicochemical properties of amphiphilic macromolecules D Abdelhamid, H Arslan, Y Zhang, KE Uhrich Polymer chemistry 5 (4), 1457-1462, 2014 | 40 | 2014 |
NO-releasing STAT3 inhibitors suppress BRAF-mutant melanoma growth TS Kaoud, AM Mohassab, HA Hassan, C Yan, SX Van Ravenstein, ... European Journal of Medicinal Chemistry 186, 111885, 2020 | 32 | 2020 |
In silico design of anti-atherogenic biomaterials DR Lewis, V Kholodovych, MD Tomasini, D Abdelhamid, LK Petersen, ... Biomaterials 34 (32), 7950-7959, 2013 | 26 | 2013 |
Novel 4-(piperazin-1-yl) quinolin-2 (1H)-one bearing thiazoles with antiproliferative activity through VEGFR-2-TK inhibition A Hassan, M Badr, HA Hassan, D Abdelhamid, GEDA Abuo‐Rahma Bioorganic & Medicinal Chemistry 40, 116168, 2021 | 25 | 2021 |
Discovery of antiproliferative and anti-FAK inhibitory activity of 1, 2, 4-triazole derivatives containing acetamido carboxylic acid skeleton M Mustafa, GEDA Abuo-Rahma, AA Abd El-Hafeez, ER Ahmed, ... Bioorganic & medicinal chemistry letters 40, 127965, 2021 | 24 | 2021 |
Polymer brain-nanotherapeutics for multipronged inhibition of microglial α-synuclein aggregation, activation, and neurotoxicity NK Bennett, R Chmielowski, DS Abdelhamid, JJ Faig, N Francis, J Baum, ... Biomaterials 111, 179-189, 2016 | 24 | 2016 |
A first-in-class anticancer dual HDAC2/FAK inhibitors bearing hydroxamates/benzamides capped by pyridinyl-1, 2, 4-triazoles M Mustafa, AA Abd El-Hafeez, D Abdelhamid, GD Katkar, YA Mostafa, ... European journal of medicinal chemistry 222, 113569, 2021 | 22 | 2021 |