| Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators Y Yu, J Khan, C Khanna, L Helman, PS Meltzer, G Merlino Nature medicine 10 (2), 175-181, 2004 | 743 | 2004 |
| Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models JGT Vi, AT Cheuk, PS Tsang, JY Chung, YK Song, K Desai, Y Yu, ... The Journal of clinical investigation 119 (11), 3395-3407, 2009 | 363 | 2009 |
| The homeoprotein six1 transcriptionally activates multiple protumorigenic genes but requires ezrin to promote metastasis Y Yu, E Davicioni, TJ Triche, G Merlino Cancer research 66 (4), 1982-1989, 2006 | 193 | 2006 |
| Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis R Sharp, JA Recio, C Jhappan, T Otsuka, S Liu, Y Yu, W Liu, M Anver, ... Nature medicine 8 (11), 1276-1280, 2002 | 171 | 2002 |
| AXL/AKT axis mediated-resistance to BRAF inhibitor depends on PTEN status in melanoma Q Zuo, J Liu, L Huang, Y Qin, T Hawley, C Seo, G Merlino, Y Yu Oncogene 37 (24), 3275-3289, 2018 | 104 | 2018 |
| Constitutive c-Met signaling through a nonautocrine mechanism promotes metastasis in a transgenic transplantation model Y Yu, G Merlino Cancer research 62 (10), 2951-2956, 2002 | 76 | 2002 |
| LFIRE-1/HFREP-1, a liver-specific gene, is frequently downregulated and has growth suppressor activity in hepatocellular carcinoma J Yan, Y Yu, N Wang, Y Chang, H Ying, W Liu, J He, S Li, W Jiang, Y Li, ... Oncogene 23 (10), 1939-1949, 2004 | 71 | 2004 |
| Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene Y Yu, P Zeng, J Xiong, Z Liu, SL Berger, G Merlino PLoS One 5 (9), e12710, 2010 | 63 | 2010 |
| Massively Parallel Sequencing Reveals an Accumulation of De Novo Mutations and an Activating Mutation of LPAR1 in a Patient with Metastatic Neuroblastoma JS Wei, P Johansson, L Chen, YK Song, C Tolman, S Li, L Hurd, ... PloS one 8 (10), e77731, 2013 | 34 | 2013 |
| PTEN dual lipid-and protein-phosphatase function in tumor progression A Liu, Y Zhu, W Chen, G Merlino, Y Yu Cancers 14 (15), 3666, 2022 | 32 | 2022 |
| The function of NK cells in tumor metastasis and NK cell-based immunotherapy Y Yu Cancers 15 (8), 2323, 2023 | 28 | 2023 |
| PHLPP1 mediates melanoma metastasis suppression through repressing AKT2 activation Y Yu, M Dai, A Lu, E Yu, G Merlino Oncogene 37 (17), 2225-2236, 2018 | 25 | 2018 |
| Ezrin mediates both HGF/Met autocrine and non‐autocrine signaling‐induced metastasis in melanoma L Huang, Y Qin, Q Zuo, K Bhatnagar, J Xiong, G Merlino, Y Yu International journal of cancer 142 (8), 1652-1663, 2018 | 22 | 2018 |
| Identification of novel genes and pathways in carotid atheroma using integrated bioinformatic methods W Nai, D Threapleton, J Lu, K Zhang, H Wu, Y Fu, Y Wang, Z Ou, L Shan, ... Scientific reports 6 (1), 18764, 2016 | 21 | 2016 |
| Cloning and characterization of F-LANa, upregulated in human liver cancer H Ying, Y Yu, Y Xu Biochemical and Biophysical Research Communications 286 (2), 394-400, 2001 | 17 | 2001 |
| Targeting the SHP2 phosphatase promotes vascular damage and inhibition of tumor growth Y Wang, O Salvucci, H Ohnuki, AD Tran, T Ha, JX Feng, M DiPrima, ... EMBO Molecular Medicine 13 (7), e14089, 2021 | 16 | 2021 |
| Antisense of ATP synthase subunit e inhibits the growth of human hepatocellular carcinoma cells. H Ying, Y Yu, Y Xu Oncology research 12 (11-12), 485-490, 2001 | 15 | 2001 |
| PERK mediates resistance to BRAF inhibition in melanoma with impaired PTEN Y Qin, Q Zuo, L Huang, L Huang, G Merlino, Y Yu NPJ Precision Oncology 5 (1), 68, 2021 | 10 | 2021 |
| A novel combination treatment against melanoma with NRAS mutation and therapy resistance Y Yu EMBO Molecular Medicine 10 (5), e8573, 2018 | 7 | 2018 |
| Ez-metastasizing: the crucial roles of Ezrin in metastasis RGM Buenaventura, G Merlino, Y Yu Cells 12 (12), 1620, 2023 | 6 | 2023 |
