Ten years of pathway analysis: current approaches and outstanding challenges P Khatri, M Sirota, AJ Butte PLoS computational biology 8 (2), e1002375, 2012 | 1768 | 2012 |
A systems biology approach for pathway level analysis S Draghici, P Khatri, AL Tarca, K Amin, A Done, C Voichita, C Georgescu, ... Genome research 17 (10), 1537-1545, 2007 | 1359 | 2007 |
A novel signaling pathway impact analysis AL Tarca, S Draghici, P Khatri, SS Hassan, P Mittal, J Kim, CJ Kim, ... Bioinformatics 25 (1), 75-82, 2009 | 1178 | 2009 |
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans PS Arunachalam, F Wimmers, CKP Mok, RAPM Perera, M Scott, T Hagan, ... Science 369 (6508), 1210-1220, 2020 | 1119 | 2020 |
Ontological analysis of gene expression data: current tools, limitations, and open problems P Khatri, S Drăghici Bioinformatics 21 (18), 3587-3595, 2005 | 1112 | 2005 |
Reliability and reproducibility issues in DNA microarray measurements S Draghici, P Khatri, AC Eklund, Z Szallasi TRENDS in Genetics 22 (2), 101-109, 2006 | 785 | 2006 |
Global functional profiling of gene expression S Draghici, P Khatri, RP Martins, GC Ostermeier, SA Krawetz Genomics 81 (2), 98-104, 2003 | 748 | 2003 |
Spermatozoal RNA profiles of normal fertile men GC Ostermeier, DJ Dix, D Miller, P Khatri, SA Krawetz The Lancet 360 (9335), 772-777, 2002 | 629 | 2002 |
Profiling gene expression using onto-express P Khatri, S Draghici, GC Ostermeier, SA Krawetz Genomics 79 (2), 266-270, 2002 | 574 | 2002 |
Cell type–specific gene expression differences in complex tissues SS Shen-Orr, R Tibshirani, P Khatri, DL Bodian, F Staedtler, NM Perry, ... Nature methods 7 (4), 287-289, 2010 | 550 | 2010 |
NetPath: a public resource of curated signal transduction pathways K Kandasamy, SS Mohan, R Raju, S Keerthikumar, GSS Kumar, ... Genome biology 11, 1-9, 2010 | 538 | 2010 |
Onto-tools, the toolkit of the modern biologist: onto-express, onto-compare, onto-design and onto-translate S Draghici, P Khatri, P Bhavsar, A Shah, SA Krawetz, MA Tainsky Nucleic acids research 31 (13), 3775-3781, 2003 | 446 | 2003 |
Genome-wide expression for diagnosis of pulmonary tuberculosis: a multicohort analysis TE Sweeney, L Braviak, CM Tato, P Khatri The Lancet Respiratory Medicine 4 (3), 213-224, 2016 | 417 | 2016 |
Systems vaccinology of the BNT162b2 mRNA vaccine in humans PS Arunachalam, MKD Scott, T Hagan, C Li, Y Feng, F Wimmers, ... Nature 596 (7872), 410-416, 2021 | 414 | 2021 |
SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer PK Mazur, N Reynoird, P Khatri, PWTC Jansen, AW Wilkinson, S Liu, ... Nature 510 (7504), 283-287, 2014 | 409 | 2014 |
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors NS Jahchan, JT Dudley, PK Mazur, N Flores, D Yang, A Palmerton, ... Cancer discovery 3 (12), 1364-1377, 2013 | 393 | 2013 |
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma PK Mazur, A Herner, SS Mello, M Wirth, S Hausmann, FJ Sánchez-Rivera, ... Nature medicine 21 (10), 1163-1171, 2015 | 385 | 2015 |
A clinically meaningful metric of immune age derived from high-dimensional longitudinal monitoring A Alpert, Y Pickman, M Leipold, Y Rosenberg-Hasson, X Ji, R Gaujoux, ... Nature medicine 25 (3), 487-495, 2019 | 379 | 2019 |
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains JV Pluvinage, MS Haney, BAH Smith, J Sun, T Iram, L Bonanno, L Li, ... Nature 568 (7751), 187-192, 2019 | 351 | 2019 |
A comprehensive time-course–based multicohort analysis of sepsis and sterile inflammation reveals a robust diagnostic gene set TE Sweeney, A Shidham, HR Wong, P Khatri Science translational medicine 7 (287), 287ra71-287ra71, 2015 | 331 | 2015 |