Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression N Ortiz-Otero, AB Clinch, J Hope, W Wang, CA Reinhart-King, MR King Oncotarget 11 (12), 1037, 2020 | 80 | 2020 |
Activation of Piezo1 sensitizes cells to TRAIL-mediated apoptosis through mitochondrial outer membrane permeability JM Hope, M Lopez-Cavestany, W Wang, CA Reinhart-King, MR King Cell Death & Disease 10 (11), 837, 2019 | 64 | 2019 |
Fluid shear stress enhances T cell activation through Piezo1 JM Hope, JA Dombroski, RS Pereles, M Lopez-Cavestany, JD Greenlee, ... BMC biology 20 (1), 61, 2022 | 51 | 2022 |
Channeling the force: Piezo1 mechanotransduction in cancer metastasis JA Dombroski, JM Hope, NS Sarna, MR King Cells 10 (11), 2815, 2021 | 45 | 2021 |
Mechanosensitive ion channels: TRPV4 and P2X7 in disseminating cancer cells JM Hope, JD Greenlee, MR King The Cancer Journal 24 (2), 84-92, 2018 | 35 | 2018 |
Circulating prostate cancer cells have differential resistance to fluid shear stress-induced cell death JM Hope, MR Bersi, JA Dombroski, AB Clinch, RS Pereles, WD Merryman, ... Journal of cell science 134 (4), jcs251470, 2021 | 30 | 2021 |
Matrix stiffness induces epithelial-to-mesenchymal transition via Piezo1-regulated calcium flux in prostate cancer cells M Lopez-Cavestany, SB Hahn, JM Hope, NT Reckhorn, JD Greenlee, ... iscience 26 (4), 2023 | 13 | 2023 |
Taxanes sensitize prostate cancer cells to TRAIL-induced apoptotic synergy via endoplasmic reticulum stress KA Grayson, JM Hope, W Wang, CA Reinhart-King, MR King Molecular cancer therapeutics 20 (5), 833-845, 2021 | 13 | 2021 |
Fluid shear stress enhances dendritic cell activation JA Dombroski, SJ Rowland, AR Fabiano, SV Knoblauch, JM Hope, ... Immunobiology 228 (6), 152744, 2023 | 6 | 2023 |
Chemical activation and mechanical sensitization of Piezo1 enhance TRAIL-mediated apoptosis in glioblastoma cells SV Knoblauch, SH Desai, JA Dombroski, NS Sarna, JM Hope, MR King ACS omega 8 (19), 16975-16986, 2023 | 6 | 2023 |
Channeling the force: Piezo1 mechanotransduction in cancer metastasis. Cells 10, 2815 JA Dombroski, JM Hope, NS Sarna, MR King | 5 | 2021 |
Mass action kinetic model of apoptosis by TRAIL-functionalized leukocytes EE Lederman, JM Hope, MR King Frontiers in Oncology 8, 410, 2018 | 5 | 2018 |
Mechanotransduction of Cancer Cells and T Cells in the Fluid Flow Environment of the Circulation JM Hope | | 2021 |